Chromosome segregation and double-strand break repair - a complex connection.
about
The cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cellsMechanisms of Rad52-independent spontaneous and UV-induced mitotic recombination in Saccharomyces cerevisiae.Meiotic cohesin SMC1β provides prophase I centromeric cohesion and is required for multiple synapsis-associated functions.Faithful after break-up: suppression of chromosomal translocations.Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.Cohesin association to replication sites depends on rad50 and promotes fork restartDiverse developmental disorders from the one ring: distinct molecular pathways underlie the cohesinopathies.Functional interplay between cohesin and Smc5/6 complexes.Regulation of recombination and genomic maintenance.Transcription facilitates sister chromatid cohesion on chromosomal arms.Roles of human AND-1 in chromosome transactions in S phaseMicrocephalin/MCPH1 associates with the Condensin II complex to function in homologous recombination repair.The Smc5-Smc6 heterodimer associates with DNA through several independent binding domains.Architecture of the Smc5/6 Complex of Saccharomyces cerevisiae Reveals a Unique Interaction between the Nse5-6 Subcomplex and the Hinge Regions of Smc5 and Smc6Cohesin's dual role in the DNA damage response: repair and checkpoint activation.Cohesion by topology: sister chromatids interlocked by DNA.Focal localization of MukBEF condensin on the chromosome requires the flexible linker region of MukF.Chl1 DNA helicase and Scc2 function in chromosome condensation through cohesin deposition.
P2860
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P2860
Chromosome segregation and double-strand break repair - a complex connection.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Chromosome segregation and double-strand break repair - a complex connection.
@ast
Chromosome segregation and double-strand break repair - a complex connection.
@en
type
label
Chromosome segregation and double-strand break repair - a complex connection.
@ast
Chromosome segregation and double-strand break repair - a complex connection.
@en
prefLabel
Chromosome segregation and double-strand break repair - a complex connection.
@ast
Chromosome segregation and double-strand break repair - a complex connection.
@en
P1476
Chromosome segregation and double-strand break repair - a complex connection.
@en
P2093
Camilla Sjögren
Lena Ström
P304
P356
10.1016/J.CEB.2007.04.003
P577
2007-04-26T00:00:00Z