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Cellular and behavioral interactions of gabapentin with alcohol dependence

Cellular and behavioral interactions of gabapentin with alcohol dependence

http://www.wikidata.org/entity/Q36805266

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Opioids, pain, the brain, and hyperkatifeia: a framework for the rational use of opioids for pain The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking Potentiation of Gamma Aminobutyric Acid Receptors (GABAAR) by Ethanol: How Are Inhibitory Receptors Affected?Neuropeptide modulation of central amygdala neuroplasticity is a key mediator of alcohol dependence.The central amygdala as an integrative hub for anxiety and alcohol use disorders Synaptic effects induced by alcohol.Don't stress about CRF: assessing the translational failures of CRF1antagonists.Pentylenetetrazol produces a state-dependent conditioned place aversion to alcohol withdrawal in mice Operant alcohol self-administration in dependent rats: focus on the vapor model Innate immune factors modulate ethanol interaction with GABAergic transmission in mouse central amygdala.Activation of σ-receptors induces binge-like drinking in Sardinian alcohol-preferring rats Altered gamma-aminobutyric acid type B receptor subunit 1 splicing in alcoholics.The dark side of emotion: the addiction perspective Gabapentin combined with naltrexone for the treatment of alcohol dependence A proof-of-concept randomized controlled study of gabapentin: effects on cannabis use, withdrawal and executive function deficits in cannabis-dependent adults.Chronic ethanol exposure decreases CB1 receptor function at GABAergic synapses in the rat central amygdala The central amygdala and alcohol: role of γ-aminobutyric acid, glutamate, and neuropeptides Separate and combined effects of gabapentin and [INCREMENT]9-tetrahydrocannabinol in humans discriminating [INCREMENT]9-tetrahydrocannabinol The Reasons for Heavy Drinking Questionnaire: Factor Structure and Validity in Alcohol-Dependent Adults Involved in Clinical Trials Corticotropin-releasing factor (CRF) and neuropeptide Y (NPY): effects on inhibitory transmission in central amygdala, and anxiety- & alcohol-related behaviors.Gabapentin potentiates sensitivity to the interoceptive effects of alcohol and increases alcohol self-administration in rats Nociceptin/orphanin FQ blockade of corticotropin-releasing factor-induced gamma-aminobutyric acid release in central amygdala is enhanced after chronic ethanol exposure.Proof-of-concept human laboratory study for protracted abstinence in alcohol dependence: effects of gabapentin.Development of pharmacotherapies for drug addiction: a Rosetta stone approach.Focus on: Neuroscience and treatment: the potential of neuroscience to inform treatment.Operant behavior and alcohol levels in blood and brain of alcohol-dependent rats.Novel anticonvulsants for reducing alcohol consumption: A review of evidence from preclinical rodent drinking models.Gabapentin treatment for alcohol dependence: a randomized clinical trial.Emerging drugs to treat alcoholism.Experimental medicine in drug addiction: towards behavioral, cognitive and neurobiological biomarkers.Ethanol and corticotropin releasing factor receptor modulation of central amygdala neurocircuitry: An update and future directions.Emerging pharmacotherapies for alcohol use disorder.Medications development for the treatment of alcohol use disorder: insights into the predictive value of animal and human laboratory models.Alcohol Dependence Disrupts Amygdalar L-Type Voltage-Gated Calcium Channel Mechanisms.Antireward, compulsivity, and addiction: seminal contributions of Dr. Athina Markou to motivational dysregulation in addiction.Synaptic targets: Chronic alcohol actions.Dysregulation of Brain Stress Systems Mediates Compulsive Alcohol Drinking.Gabapentin versus chlordiazepoxide for outpatient alcohol detoxification treatment.Gabapentin for the treatment of alcohol use disorder.Presynaptic Ethanol Actions: Potential Roles in Ethanol Seeking.

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P2860

Cellular and behavioral interactions of gabapentin with alcohol dependence

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2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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Cellular and behavioral interactions of gabapentin with alcohol dependence

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Cellular and behavioral interactions of gabapentin with alcohol dependence

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Cellular and behavioral interactions of gabapentin with alcohol dependence

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JNEUROSCI.0575-08.2008

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Journal of Neuroscience

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Cellular and behavioral interactions of gabapentin with alcohol dependence

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P2093

Andrew C Morse

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George F Koob

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George R Siggins

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Laura E O'Dell

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Marisa Roberto

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Maureen T Cruz

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Nicholas W Gilpin

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P2860

Neuroprotective and abstinence-promoting effects of acamprosate: elucidating the mechanism of action

Corticotropin-releasing factor 1 antagonists selectively reduce ethanol self-administration in ethanol-dependent rats

Gamma-aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action.

The intrinsic organization of the central extended amygdala.

Abecarnil and alprazolam reverse anxiety-like behaviors induced by ethanol withdrawal.

Newer antiepileptic drugs: possible uses in the treatment of neuropathic pain and migraine.

Role of GABA in anxiety and depression.

Reducing effect of the positive allosteric modulator of the GABA(B) receptor, GS39,783, on alcohol self-administration in alcohol-preferring rats.

Nociceptin/orphanin FQ presynaptically decreases GABAergic transmission and blocks the ethanol-induced increase of GABA release in central amygdala.

Ethanol increases GABAergic transmission at both pre- and postsynaptic sites in rat central amygdala neurons.

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5762-5771

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10.1523/JNEUROSCI.0575-08.2008

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