about
Frontotemporal lobar degeneration: old knowledge and new insight into the pathogenetic mechanisms of tau mutationsMouse models of frontotemporal dementiaTau and tauopathiesSpines, plasticity, and cognition in Alzheimer's model miceThe contribution of alpha synuclein to neuronal survival and function - Implications for Parkinson's diseaseAltered regulation of Akt signaling with murine cerebral malaria, effects on long-term neuro-cognitive function, restoration with lithium treatmentAnimal models for Alzheimer's disease and frontotemporal dementia: a perspectiveEarly axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice.Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-betaTau mutants bind tubulin heterodimers with enhanced affinity.Neuroproteomics as a promising tool in Parkinson's disease research.Targeting Abeta and tau in Alzheimer's disease, an early interim reportStaging of Alzheimer's pathology in triple transgenic mice: a light and electron microscopic analysis.Modes of Aβ toxicity in Alzheimer's disease.E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairmentA novel operant testing regimen for multi-construct cognitive characterization of a murine model of Alzheimer's amyloid-related behavioral impairmentAnalysis of tau post-translational modifications in rTg4510 mice, a model of tau pathologyENU mutagenesis screen to establish motor phenotypes in wild-type mice and modifiers of a pre-existing motor phenotype in tau mutant mice.Small molecule compounds alleviate anisomycin-induced oxidative stress injury in SH-SY5Y cells via downregulation of p66shc and Aβ1-42 expression.Co-immunoprecipitation with Tau Isoform-specific Antibodies Reveals Distinct Protein Interactions and Highlights a Putative Role for 2N Tau in Disease.Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementiaSmall-molecule mediated neuroprotection in an in situ model of tauopathy.An update on the toxicity of Abeta in Alzheimer's disease.Tau aggregation and toxicity in tauopathic neurodegenerative diseases.Relevance of transgenic mouse models to human Alzheimer disease.Effects of 17-allylamino-17-demethoxygeldanamycin (17-AAG) in transgenic mouse models of frontotemporal lobar degeneration and Alzheimer's disease.Diminished perisomatic GABAergic terminals on cortical neurons adjacent to amyloid plaques.Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology.Transgenic mouse models of Alzheimer disease: developing a better model as a tool for therapeutic interventions.Biochemistry and cell biology of tau protein in neurofibrillary degenerationAnimal models of Alzheimer disease.Animal models of neurodegenerative diseases.In vivo tracking of tau pathology using positron emission tomography (PET) molecular imaging in small animals.Invited review: Drug development for tauopathies.Modeling Alzheimer's disease with human induced pluripotent stem (iPS) cells.Neurodegenerative Disease Transmission and Transgenesis in Mice.Are tau aggregates toxic or protective in tauopathies?The CNS in inbred transgenic models of 4-repeat Tauopathy develops consistent tau seeding capacity yet focal and diverse patterns of protein deposition.Modification of Tau by 8-Nitroguanosine 3',5'-Cyclic Monophosphate (8-Nitro-cGMP): EFFECTS OF NITRIC OXIDE-LINKED CHEMICAL MODIFICATION ON TAU AGGREGATION.Tauopathy induced by low level expression of a human brain-derived tau fragment in mice is rescued by phenylbutyrate.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
A decade of tau transgenic animal models and beyond.
@ast
A decade of tau transgenic animal models and beyond.
@en
type
label
A decade of tau transgenic animal models and beyond.
@ast
A decade of tau transgenic animal models and beyond.
@en
prefLabel
A decade of tau transgenic animal models and beyond.
@ast
A decade of tau transgenic animal models and beyond.
@en
P2093
P2860
P50
P1433
P1476
A decade of tau transgenic animal models and beyond.
@en
P2093
Amy Doldissen
Andreas Wiesner
Laita Bokhari
Natasha Deters
Nicole Schonrock
P2860
P304
P356
10.1111/J.1750-3639.2007.00051.X
P577
2007-01-01T00:00:00Z