Detrimental effects of adenosine signaling in sickle cell disease.
about
Blood cells: an historical account of the roles of purinergic signallingAttenuating myocardial ischemia by targeting A2B adenosine receptorsThe role of adenosine signaling in sickle cell therapeuticsConstruction of a Plasmodium falciparum Rab-interactome identifies CK1 and PKA as Rab-effector kinases in malaria parasites.Beneficial and detrimental role of adenosine signaling in diseases and therapyThe Influence of the 1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole-4-yl Moiety on the Adenosine Receptors Affinity Profile of Pyrazolo[4,3-e][1,2,4]Triazolo[1,5-c]Pyrimidine DerivativesAdenosine receptors as drug targets--what are the challenges?Excess adenosine A2B receptor signaling contributes to priapism through HIF-1α mediated reduction of PDE5 gene expressionMetabolic Dysfunction in Heart Failure: Diagnostic, Prognostic, and Pathophysiologic Insights From Metabolomic Profiling.Adenosine signaling during acute and chronic disease statesExtracellular nucleotide and nucleoside signaling in vascular and blood diseaseAdora2b adenosine receptor engagement enhances regulatory T cell abundance during endotoxin-induced pulmonary inflammationA2B adenosine receptor contributes to penile erection via PI3K/AKT signaling cascade-mediated eNOS activation.Elevated adenosine signaling via adenosine A2B receptor induces normal and sickle erythrocyte sphingosine kinase 1 activityEquilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in miceEarly hemorrhage triggers metabolic responses that build up during prolonged shock.Defibrotide interferes with several steps of the coagulation-inflammation cycle and exhibits therapeutic potential to treat severe malariaThe LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell miceDecreased erythrocyte nucleoside transport and hENT1 transporter expression in glucose 6-phosphate dehydrogenase deficiency.Targeting iNKT cells for the treatment of sickle cell disease.Impaired erectile function in CD73-deficient mice with reduced endogenous penile adenosine productionPlasma metabolomic profiles enhance precision medicine for volunteers of normal health.Sickling cells, cyclic nucleotides, and protein kinases: the pathophysiology of urogenital disorders in sickle cell anemia.Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activationFructose 1,6-bisphosphate, a high-energy intermediate of glycolysis, attenuates experimental arthritis by activating anti-inflammatory adenosinergic pathway.Three-minute method for amino acid analysis by UHPLC and high-resolution quadrupole orbitrap mass spectrometry.A novel molecular signature for elevated tricuspid regurgitation velocity in sickle cell disease.Inflammatory targets of therapy in sickle cell disease.Elevated placental adenosine signaling contributes to the pathogenesis of preeclampsia.Extracellular adenosine signaling in molecular medicineSickle cell vaso-occlusion causes activation of iNKT cells that is decreased by the adenosine A2A receptor agonist regadenosonAdora2b adenosine receptor signaling protects during acute kidney injury via inhibition of neutrophil-dependent TNF-α releaseCD73+ regulatory T cells contribute to adenosine-mediated resolution of acute lung injury.Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia.Minireview: Multiomic candidate biomarkers for clinical manifestations of sickle cell severity: Early steps to precision medicineOriginal Research: Diametric effects of hypoxia on pathophysiology of sickle cell disease in a murine model.Hypoxia-mediated impaired erythrocyte Lands' Cycle is pathogenic for sickle cell disease.Equilibrative nucleoside transporter (ENT)-1-dependent elevation of extracellular adenosine protects the liver during ischemia and reperfusionHypoxia signaling during intestinal ischemia and inflammation.Elevated ecto-5'-nucleotidase-mediated increased renal adenosine signaling via A2B adenosine receptor contributes to chronic hypertension.
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P2860
Detrimental effects of adenosine signaling in sickle cell disease.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Detrimental effects of adenosine signaling in sickle cell disease.
@ast
Detrimental effects of adenosine signaling in sickle cell disease.
@en
type
label
Detrimental effects of adenosine signaling in sickle cell disease.
@ast
Detrimental effects of adenosine signaling in sickle cell disease.
@en
prefLabel
Detrimental effects of adenosine signaling in sickle cell disease.
@ast
Detrimental effects of adenosine signaling in sickle cell disease.
@en
P2093
P2860
P356
P1433
P1476
Detrimental effects of adenosine signaling in sickle cell disease.
@en
P2093
Danny C Alexander
Dorothy E Lewis
Guangxiu Lu
Harinder S Juneja
Holger K Eltzschig
Jiaming Wen
Lijian Tao
Louvenia Carter-Dawson
Michael V Milburn
P2860
P2888
P356
10.1038/NM.2280
P407
P577
2010-12-19T00:00:00Z
P5875
P6179
1026064448