Structures of cGMP-Dependent Protein Kinase (PKG) Iα Leucine Zippers Reveal an Interchain Disulfide Bond Important for Dimer Stability.
about
Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response.The activity of cGMP-dependent protein kinase Iα is not directly regulated by oxidation-induced disulfide formation at cysteine 43.Targeting Mitochondrial Calcium Handling and Reactive Oxygen Species in Heart Failure.Examining a role for PKG Iα oxidation in the pathogenesis of cardiovascular dysfunction during diet-induced obesity.Structural Basis of Analog Specificity in PKG I and II.Molecular recognition of carboxylates in the protein leucine zipper by a multivalent supramolecular ligand: residue-specific, sensitive and label-free probing by UV resonance Raman spectroscopy.NMR insight into myosin-binding subunit coiled-coil structure reveals binding interface with protein kinase G-Iα leucine zipper in vascular function.An N-terminally truncated form of cyclic GMP-dependent protein kinase Iα (PKG Iα) is monomeric, autoinhibited, and provides a model for activation.Structural basis for selective inhibition of human PKG Iα by the balanol-like compound N46.
P2860
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P2860
Structures of cGMP-Dependent Protein Kinase (PKG) Iα Leucine Zippers Reveal an Interchain Disulfide Bond Important for Dimer Stability.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Structures of cGMP-Dependent P ...... Important for Dimer Stability.
@ast
Structures of cGMP-Dependent P ...... Important for Dimer Stability.
@en
type
label
Structures of cGMP-Dependent P ...... Important for Dimer Stability.
@ast
Structures of cGMP-Dependent P ...... Important for Dimer Stability.
@en
prefLabel
Structures of cGMP-Dependent P ...... Important for Dimer Stability.
@ast
Structures of cGMP-Dependent P ...... Important for Dimer Stability.
@en
P2093
P2860
P1433
P1476
Structures of cGMP-Dependent P ...... Important for Dimer Stability.
@en
P2093
Albert S Reger
Darren E Casteel
Elaine Guo
Liying Qin
Matthew P Yang
Peter Zwart
P2860
P304
P356
10.1021/ACS.BIOCHEM.5B00572
P407
P577
2015-07-15T00:00:00Z