Harnessing calcineurin as a novel anti-infective agent against invasive fungal infections.
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Calcium/calmodulin kinase1 and its relation to thermotolerance and HSP90 in Sporothrix schenckii: an RNAi and yeast two-hybrid studyCalcineurin Orchestrates Hyphal Growth, Septation, Drug Resistance and Pathogenesis of Aspergillus fumigatus: Where Do We Go from Here?Activation of an essential calcium signaling pathway in Saccharomyces cerevisiae by Kch1 and Kch2, putative low-affinity potassium transportersSynergistic combinations of antifungals and anti-virulence agents to fight against Candida albicansRegulatory roles of phosphorylation in model and pathogenic fungiReverse genetics in Candida albicans predicts ARF cycling is essential for drug resistance and virulencePKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurinHsp90 orchestrates stress response signaling governing fungal drug resistanceAssociation of calcineurin with the COPI protein Sec28 and the COPII protein Sec13 revealed by quantitative proteomicsCalcineurin is required for pseudohyphal growth, virulence, and drug resistance in Candida lusitaniaeGlobal analysis of the evolution and mechanism of echinocandin resistance in Candida glabrataFunctional characterization of an Aspergillus fumigatus calcium transporter (PmcA) that is essential for fungal infectionCalcium-activated-calcineurin reduces the In vitro and In vivo sensitivity of fluconazole to Candida albicans via Rta2pFunctional characterization of calcineurin homologs PsCNA1/PsCNB1 in Puccinia striiformis f. sp. tritici using a host-induced RNAi systemGenetic and genomic architecture of the evolution of resistance to antifungal drug combinationsPosaconazole exhibits in vitro and in vivo synergistic antifungal activity with caspofungin or FK506 against Candida albicansHsp21 potentiates antifungal drug tolerance in Candida albicansPhosphorylation of Calcineurin at a novel serine-proline rich region orchestrates hyphal growth and virulence in Aspergillus fumigatusCharacterization of the FKBP12-Encoding Genes in Aspergillus fumigatusCalcineurin Targets Involved in Stress Survival and Fungal VirulenceMicrobial Pathogens in the Fungal KingdomIdentification of possible targets of the Aspergillus fumigatus CRZ1 homologue, CrzA.The triphenylethylenes, a novel class of antifungals.Combining ChIP-chip and expression profiling to model the MoCRZ1 mediated circuit for Ca/calcineurin signaling in the rice blast fungus.'Popping the clutch': novel mechanisms regulating sexual development in Cryptococcus neoformans.Pheromone independent unisexual development in Cryptococcus neoformans.Roles of calcineurin and Crz1 in antifungal susceptibility and virulence of Candida glabrata.Cryptococcus neoformans and Cryptococcus gattii, the etiologic agents of cryptococcosis.Defects in phosphate acquisition and storage influence virulence of Cryptococcus neoformans.Heptahelical receptors GprC and GprD of Aspergillus fumigatus Are essential regulators of colony growth, hyphal morphogenesis, and virulence.The involvement of the Mid1/Cch1/Yvc1 calcium channels in Aspergillus fumigatus virulenceThe calcineurin signaling network evolves via conserved kinase-phosphatase modules that transcend substrate identityCalcineurin controls hyphal growth, virulence, and drug tolerance of Candida tropicalis.Chitin synthesis and fungal pathogenesis.Antifungal drug discovery: the process and outcomes.Regulatory circuitry governing fungal development, drug resistance, and disease.Elucidating drug resistance in human fungal pathogens.Hsp90 is involved in apoptosis of Candida albicans by regulating the calcineurin-caspase apoptotic pathway.Putative calcium channels CchA and MidA play the important roles in conidiation, hyphal polarity and cell wall components in Aspergillus nidulans.
P2860
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P2860
Harnessing calcineurin as a novel anti-infective agent against invasive fungal infections.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Harnessing calcineurin as a no ...... st invasive fungal infections.
@en
type
label
Harnessing calcineurin as a no ...... st invasive fungal infections.
@en
prefLabel
Harnessing calcineurin as a no ...... st invasive fungal infections.
@en
P2093
P356
P1476
Harnessing calcineurin as a no ...... st invasive fungal infections.
@en
P2093
Jennifer L Reedy
Robert A Cramer
William J Steinbach
P2888
P304
P356
10.1038/NRMICRO1680
P407
P577
2007-06-01T00:00:00Z