JAK2, but not Src family kinases, is required for STAT, ERK, and Akt signaling in response to growth hormone in preadipocytes and hepatoma cells.
about
C/EBPβ mediates growth hormone-regulated expression of multiple target genesJAK2 activation by growth hormone and other cytokinesBiological effects of growth hormone on carbohydrate and lipid metabolism.In vivo targeting of the growth hormone receptor (GHR) Box1 sequence demonstrates that the GHR does not signal exclusively through JAK2.Deletion of IGF-I receptor (IGF-IR) in primary osteoblasts reduces GH-induced STAT5 signaling.Minireview: mechanisms of growth hormone-mediated gene regulation.Growth hormone potentiates 17β-estradiol-dependent breast cancer cell proliferation independently of IGF-I receptor signaling.MERTK signaling in the retinal pigment epithelium regulates the tyrosine phosphorylation of GDP dissociation inhibitor alpha from the GDI/CHM family of RAB GTPase effectors.Genetic Defects in the Growth Hormone-IGF-I Axis Causing Growth Hormone Insensitivity and Impaired Linear GrowthInterruption of growth hormone signaling via SHC and ERK in 3T3-F442A preadipocytes upon knockdown of insulin receptor substrate-1.Growth hormone and insulin-like growth factor-I alter hippocampal excitatory synaptic transmission in young and old rats.Dysregulated STAT1-SOCS1 control of JAK2 promotes mammary luminal progenitor cell survival and drives ERα(+) tumorigenesis.AKT/eNOS signaling module functions as a potential feedback loop in the growth hormone signaling pathway.Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways.
P2860
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P2860
JAK2, but not Src family kinases, is required for STAT, ERK, and Akt signaling in response to growth hormone in preadipocytes and hepatoma cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
JAK2, but not Src family kinas ...... adipocytes and hepatoma cells.
@en
type
label
JAK2, but not Src family kinas ...... adipocytes and hepatoma cells.
@en
prefLabel
JAK2, but not Src family kinas ...... adipocytes and hepatoma cells.
@en
P2093
P2860
P356
P1476
JAK2, but not Src family kinas ...... adipocytes and hepatoma cells.
@en
P2093
Christin Carter-Su
Nathan J Lanning
P2860
P304
P356
10.1210/ME.2008-0015
P577
2008-05-22T00:00:00Z