The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes.
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Restriction beyond the restriction point: mitogen requirement for G2 passageThe E3 ubiquitin ligase UBE3A is an integral component of the molecular circadian clock through regulating the BMAL1 transcription factorThe region of the HPV E7 oncoprotein homologous to adenovirus E1a and Sv40 large T antigen contains separate domains for Rb binding and casein kinase II phosphorylationInhibition of p53 DNA binding by human papillomavirus E6 proteinsPurification and characterization of human papillomavirus type 16 E7 protein with preferential binding capacity to the underphosphorylated form of retinoblastoma gene productHomologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteinsThe global transcriptional effects of the human papillomavirus E6 protein in cervical carcinoma cell lines are mediated by the E6AP ubiquitin ligase.Gps2, a protein partner for human papillomavirus E6 proteinsInteraction of zyxin, a focal adhesion protein, with the e6 protein from human papillomavirus type 6 results in its nuclear translocationHuman papillomavirus oncoprotein E6 inactivates the transcriptional coactivator human ADA3Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligaseMCG10, a novel p53 target gene that encodes a KH domain RNA-binding protein, is capable of inducing apoptosis and cell cycle arrest in G(2)-MThe E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradationHuman papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activityViruses associated with human cancerBinding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor proteinModulation of type M2 pyruvate kinase activity by the human papillomavirus type 16 E7 oncoproteinHemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and involves a direct interaction between beta4 and the bullous pemphigoid antigen 180The viral etiology of AIDS-associated malignanciesHepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotypeStructural Insights into a Wildtype Domain of the Oncoprotein E6 and Its Interaction with a PDZ DomainEffect of transforming viruses on molecular mechanisms associated with cancerDegradation of p53 by human Alphapapillomavirus E6 proteins shows a stronger correlation with phylogeny than oncogenicityStructure based identification and characterization of flavonoids that disrupt human papillomavirus-16 E6 functionA Small Molecule Inhibitor Selectively Induces Apoptosis in Cells Transformed by High Risk Human Papilloma VirusesMouse p53 represses the rat brain creatine kinase gene but activates the rat muscle creatine kinase geneThe role of Cdc25A in the regulation of cell proliferation and apoptosisAccumulation of human papillomavirus type 16 E7 protein bypasses G1 arrest induced by serum deprivation and by the cell cycle inhibitor p21The human papillomavirus E7 proteins associate with p190RhoGAP and alter its function.Papillomavirus E6 oncoproteins.Human papillomavirus 16 E5 induces bi-nucleated cell formation by cell-cell fusion.In silico mechanistic analysis of IRF3 inactivation and high-risk HPV E6 species-dependent drug response.HPV16 E7 protein and hTERT proteins defective for telomere maintenance cooperate to immortalize human keratinocytesHeparin (GAG-hed) inhibits LCR activity of human papillomavirus type 18 by decreasing AP1 binding.The human papillomavirus type 16 E7 gene product interacts with and trans-activates the AP1 family of transcription factorsInteraction of the human papillomavirus type 16 E6 oncoprotein with wild-type and mutant human p53 proteinsHuman papillomavirus E6 and Myc proteins associate in vivo and bind to and cooperatively activate the telomerase reverse transcriptase promoterGene expression profile of cervical and skin tissues from human papillomavirus type 16 E6 transgenic mice.Reduction in the copy number and expression level of the recurrent human papillomavirus integration gene fragile histidine triad (FHIT) predicts the transition of cervical lesions.Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product.
P2860
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P2860
The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
The E6 and E7 genes of the hum ...... f primary human keratinocytes.
@en
type
label
The E6 and E7 genes of the hum ...... f primary human keratinocytes.
@en
prefLabel
The E6 and E7 genes of the hum ...... f primary human keratinocytes.
@en
P2093
P2860
P1433
P1476
The E6 and E7 genes of the hum ...... f primary human keratinocytes.
@en
P2093
P2860
P304
P407
P577
1989-10-01T00:00:00Z