The regions important for the activator and repressor functions of herpes simplex virus type 1 alpha protein ICP27 map to the C-terminal half of the molecule.
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Herpes simplex virus IE63 (ICP27) protein interacts with spliceosome-associated protein 145 and inhibits splicing prior to the first catalytic stepDetermination and analysis of the complete nucleotide sequence of human herpesvirusThe interplay between human herpes simplex virus infection and the apoptosis and necroptosis cell death pathwaysHsc70 focus formation at the periphery of HSV-1 transcription sites requires ICP27.Analysis of the phosphorylation sites of herpes simplex virus type 1 regulatory protein ICP27.Regulation of viral gene expression by duck enteritis virus UL54.Herpesvirus mRNAs are sorted for export via Crm1-dependent and -independent pathwaysProcessing of alpha-globin and ICP0 mRNA in cells infected with herpes simplex virus type 1 ICP27 mutants.The conserved carboxyl-terminal half of herpes simplex virus type 1 regulatory protein ICP27 is dispensable for viral growth in the presence of compensatory mutationsIdentification of an export control sequence and a requirement for the KH domains in ICP27 from herpes simplex virus type 1Accumulation of herpes simplex virus type 1 early and leaky-late proteins correlates with apoptosis prevention in infected human HEp-2 cells.Identification and transcriptional analyses of the UL3 and UL4 genes of equine herpesvirus 1, homologs of the ICP27 and glycoprotein K genes of herpes simplex virus.UL54-null pseudorabies virus is attenuated in mice but productively infects cells in cultureMapping of functional regions in the amino-terminal portion of the herpes simplex virus ICP27 regulatory protein: importance of the leucine-rich nuclear export signal and RGG Box RNA-binding domain.ICP27 interacts with the C-terminal domain of RNA polymerase II and facilitates its recruitment to herpes simplex virus 1 transcription sites, where it undergoes proteasomal degradation during infection.Functional analysis of Epstein-Barr virus SM protein: identification of amino acids essential for structure, transactivation, splicing inhibition, and virion productionICP27 mediates HSV RNA export by shuttling through a leucine-rich nuclear export signal and binding viral intronless RNAs through an RGG motifIntracellular localization of the herpes simplex virus type 1 major transcriptional regulatory protein, ICP4, is affected by ICP27Evaluation of colocalization interactions between the IE110, IE175, and IE63 transactivator proteins of herpes simplex virus within subcellular punctate structuresRegulatory function of the equine herpesvirus 1 ICP27 gene product.Arginine-rich regions succeeding the nuclear localization region of the herpes simplex virus type 1 regulatory protein ICP27 are required for efficient nuclear localization and late gene expressionThe C-terminal repressor region of herpes simplex virus type 1 ICP27 is required for the redistribution of small nuclear ribonucleoprotein particles and splicing factor SC35; however, these alterations are not sufficient to inhibit host cell splicinHerpes simplex virus trans-regulatory protein ICP27 stabilizes and binds to 3' ends of labile mRNA.The herpes simplex virus type 1 regulatory protein ICP27 coimmunoprecipitates with anti-Sm antiserum, and the C terminus appears to be required for this interactionThe structure of the folded domain from the signature multifunctional protein ICP27 from herpes simplex virus-1 reveals an intertwined dimer.Herpes simplex virus ICP27 increases translation of a subset of viral late mRNAs.Identification and analysis of discrete functional domains in the pro region of pre-pro-transforming growth factor beta 1.The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection.Amino acid substitution mutations in the herpes simplex virus ICP27 protein define an essential gene regulation function.Cooperativity among herpes simplex virus type 1 immediate-early regulatory proteins: ICP4 and ICP27 affect the intracellular localization of ICP0Herpes simplex virus inhibits host cell splicing, and regulatory protein ICP27 is required for this effect.The equine herpesvirus 1 (EHV-1) UL3 gene, an ICP27 homolog, is necessary for full activation of gene expression directed by an EHV-1 late promoterCharacterization of the regulatory functions of varicella-zoster virus open reading frame 4 gene product.The conserved DNA-binding domains encoded by the herpes simplex virus type 1 ICP4, pseudorabies virus IE180, and varicella-zoster virus ORF62 genes recognize similar sites in the corresponding promotersThe acidic amino-terminal region of herpes simplex virus type 1 alpha protein ICP27 is required for an essential lytic function.Mutations in the activation region of herpes simplex virus regulatory protein ICP27 can be trans dominant.Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27.The repressing and enhancing functions of the herpes simplex virus regulatory protein ICP27 map to C-terminal regions and are required to modulate viral gene expression very early in infection.Alternate promoter selection within a human cytomegalovirus immediate-early and early transcription unit (UL119-115) defines true late transcripts containing open reading frames for putative viral glycoproteinsKaposi's sarcoma-associated herpesvirus ORF57 in viral RNA processing.
P2860
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P2860
The regions important for the activator and repressor functions of herpes simplex virus type 1 alpha protein ICP27 map to the C-terminal half of the molecule.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
The regions important for the ...... terminal half of the molecule.
@en
type
label
The regions important for the ...... terminal half of the molecule.
@en
prefLabel
The regions important for the ...... terminal half of the molecule.
@en
P2093
P2860
P1433
P1476
The regions important for the ...... terminal half of the molecule.
@en
P2093
M A Hardwicke
P J Vaughan
R E Sekulovich
R M Sandri-Goldin
R O'Conner
P2860
P304
P407
P577
1989-11-01T00:00:00Z