Role of negatively charged residues in the fifth and sixth transmembrane domains of the catalytic subunit of gastric H+,K+-ATPase.
about
Manganese selectivity of pmr1, the yeast secretory pathway ion pump, is defined by residue gln783 in transmembrane segment 6. Residue Asp778 is essential for cation transport.The non-gastric H,K-ATPase is oligomycin-sensitive and can function as an H+,NH4(+)-ATPaseH,K-ATPase alpha subunit C-terminal membrane topology: epitope tags in the insect cell expression system.Novel approaches to the pharmacological blockade of gastric acid secretion.Role of potassium in acid secretionRole of transmembrane segment M8 in the biogenesis and function of yeast plasma-membrane H(+)-ATPaseNuclear Na+/K+-ATPase plays an active role in nucleoplasmic Ca2+ homeostasis.An ion gating mechanism of gastric H,K-ATPase based on molecular dynamics simulations.A chimeric gastric H+,K+-ATPase inhibitable with both ouabain and SCH 28080.Mutational study on the roles of disulfide bonds in the beta-subunit of gastric H+,K+-ATPase.Heterologous expression of Na(+)-K(+)-ATPase in insect cells: intracellular distribution of pump subunits.Identification of the site of inhibition by omeprazole of a alpha-beta fusion protein of the H,K-ATPase using site-directed mutagenesis.Mutational analysis of putative SCH 28080 binding sites of the gastric H+,K+-ATPase.The negative charge of glutamic acid-820 in the gastric H+,K+-ATPase alpha-subunit is essential for K+ activation of the enzyme activity.Constitutive activation of gastric H+,K+-ATPase by a single mutationThe cadmium transport sites of CadA, the Cd2+-ATPase from Listeria monocytogenes.Chimeras of X+, K+-ATPases. The M1-M6 region of Na+, K+-ATPase is required for Na+-activated ATPase activity, whereas the M7-M10 region of H+, K+-ATPase is involved in K+ de-occlusion.K(+)-independent gastric H(+),K(+)-atpase activity. Dissociation of K(+)-independent dephosphorylation and preference for the E1 conformation by combined mutagenesis of transmembrane glutamate residues.A model of reversible inhibitors in the gastric H+/K+-ATPase binding site determined by rotational echo double resonance NMR.Involvement of the cytoplasmic loop L6-7 in the entry mechanism for transport of Ca2+ through the sarcoplasmic reticulum Ca2+-ATPase.The cavity structure for docking the K(+)-competitive inhibitors in the gastric proton pump.Identification of the transmembrane metal binding site in Cu+-transporting PIB-type ATPases.The role of loop 6/7 in folding and functional performance of Na,K-ATPase.The cytoplasmic loop located between transmembrane segments 6 and 7 controls activation by Ca2+ of sarcoplasmic reticulum Ca2+-ATPase.
P2860
Q27930906-92FF45A8-57A5-48C0-A8B6-7B153722A48DQ28568623-892246D6-0477-4775-A22E-E4A933DC1A3DQ30708883-97FD2031-E862-407F-968F-02560DC67D97Q36120771-53F37AEE-3C8A-49A5-BBDC-B6773D2971C2Q36252012-35D32068-E1BC-40BD-A082-A59D7AC3E88DQ36495106-C4BA35D0-533F-42D5-851A-675E78C942E2Q36648248-6EA53749-DAB7-4AC2-9B72-C92E69E128DFQ36856448-9D45AD88-62C0-4B56-AF7C-B5D3A9D3D248Q38327479-0BAFAE4F-D362-4861-96A9-EC1BC54160D0Q40742973-6EC85EDE-B67B-4775-B0B6-49D8DD054CCFQ40786470-53647E2E-D49E-4D80-9ABF-CD8C48229268Q41037593-F8AE9B37-4904-4B11-B208-57FED99D27BCQ41099747-8D9114A0-C624-48DF-BD6B-BCA443367AA4Q41829313-D2A2D03F-1815-4CA8-A833-AFE6C1E13FE0Q42645434-3C14B0A0-830B-49F0-8473-6718D9B49035Q42691139-5E494521-C973-4866-9268-F96E6B1FBD7BQ43559851-83E51F46-6E7A-4047-B4CD-21E240A4E783Q43686305-F40EC7F7-CC4C-44F6-B177-6B6E9BD7BB36Q43691957-C994574E-0CD9-444E-95FF-963ADA54C9A4Q43860681-71F8CD2A-DFF3-459B-8B52-838363AFE0C4Q44709166-D78C6713-6A08-4922-BDD9-2459A7C67F61Q45115007-0A792064-86F8-431D-8954-47B7BB2838BEQ46130612-CE7ABA1F-F369-4561-B063-BA0F619865CCQ47761747-7D51F9D7-0BF3-4F21-B1D5-CFE7D02E1B58
P2860
Role of negatively charged residues in the fifth and sixth transmembrane domains of the catalytic subunit of gastric H+,K+-ATPase.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Role of negatively charged res ...... bunit of gastric H+,K+-ATPase.
@en
type
label
Role of negatively charged res ...... bunit of gastric H+,K+-ATPase.
@en
prefLabel
Role of negatively charged res ...... bunit of gastric H+,K+-ATPase.
@en
P2093
P2860
P356
P1476
Role of negatively charged res ...... bunit of gastric H+,K+-ATPase.
@en
P2093
C H Klaassen
H G Swarts
J A Fransen
J J De Pont
P2860
P304
29764-29772
P356
10.1074/JBC.271.47.29764
P407
P577
1996-11-01T00:00:00Z