The cavity structure for docking the K(+)-competitive inhibitors in the gastric proton pump.
about
The gastric HK-ATPase: structure, function, and inhibitionConformational rearrangement of gastric H(+),K(+)-ATPase induced by an acid suppressantThe renal H+-K+-ATPases: physiology, regulation, and structureAnalysis of the gastric H,K ATPase for ion pathways and inhibitor binding sites.Characterization of a novel potassium-competitive acid blocker of the gastric H,K-ATPase, 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine monofumarate (TAK-438).Novel approaches to the pharmacological blockade of gastric acid secretion.Role of potassium in acid secretionPharmacokinetics and pharmacodynamics of the proton pump inhibitors.ATP4A gene regulatory network for fine-tuning of proton pump and ion channels.The renal H+, K+-ATPases as therapeutic targets.Emerging drugs for gastroesophageal reflux disease.Gastric acid, calcium absorption, and their impact on bone health.Characteristics of the K+-competitive H+,K+-ATPase inhibitor AZD0865 in isolated rat gastric glands.The cryo-EM structure of gastric H+,K+-ATPase with bound BYK99, a high-affinity member of K+-competitive, imidazo[1,2-a]pyridine inhibitorsThe binding selectivity of vonoprazan (TAK-438) to the gastric H+, K+ -ATPase.
P2860
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P2860
The cavity structure for docking the K(+)-competitive inhibitors in the gastric proton pump.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
The cavity structure for docking the K
@nl
The cavity structure for docki ...... rs in the gastric proton pump.
@en
type
label
The cavity structure for docking the K
@nl
The cavity structure for docki ...... rs in the gastric proton pump.
@en
prefLabel
The cavity structure for docking the K
@nl
The cavity structure for docki ...... rs in the gastric proton pump.
@en
P2093
P2860
P356
P1476
The cavity structure for docki ...... rs in the gastric proton pump.
@en
P2093
Anna Morisato
Ayumi Yoshida
Haruo Ogawa
Hiroaki Yashiro
Magotoshi Morii
Noriaki Takeguchi
Shinji Asano
Yusuke Kobayashi
P2860
P304
13968-13975
P356
10.1074/JBC.M308934200
P407
P577
2003-12-29T00:00:00Z