Heterogeneous nuclear ribonucleoprotein A1 regulates cyclin D1 and c-myc internal ribosome entry site function through Akt signaling.
about
Cap-Independent Translation in Hematological MalignanciesPhosphorylation-mediated regulation of alternative splicing in cancerAlternative pre-mRNA splicing regulation in cancer: pathways and programs unhingedPromoter-Dependent Translation Controlled by p54nrb and hnRNPM during Myoblast DifferentiationThe hnRNA-binding proteins hnRNP L and PTB are required for efficient translation of the Cat-1 arginine/lysine transporter mRNA during amino acid starvationhnRNP A1 mediates the activation of the IRES-dependent SREBP-1a mRNA translation in response to endoplasmic reticulum stressCharacterization of the internal IRES element of the zebrafish connexin55.5 reveals functional implication of the polypyrimidine tract binding protein.PRMT5 regulates IRES-dependent translation via methylation of hnRNP A1.Northwestern profiling of potential translation-regulatory proteins in human breast epithelial cells and malignant breast tissues: evidence for pathological activation of the IGF1R IRES.p38 MAP kinase-dependent regulation of the expression level and subcellular distribution of heterogeneous nuclear ribonucleoprotein A1 and its involvement in cellular senescence in normal human fibroblasts.The human IGF1R IRES likely operates through a Shine-Dalgarno-like interaction with the G961 loop (E-site) of the 18S rRNA and is kinetically modulated by a naturally polymorphic polyU loop.IL-6-induced enhancement of c-Myc translation in multiple myeloma cells: critical role of cytoplasmic localization of the rna-binding protein hnRNP A1.Cellular IRES-mediated translation: the war of ITAFs in pathophysiological states.Novel RNA chaperone domain of RNA-binding protein La is regulated by AKT phosphorylationPhosphomimetic substitution of heterogeneous nuclear ribonucleoprotein A1 at serine 199 abolishes AKT-dependent internal ribosome entry site-transacting factor (ITAF) function via effects on strand annealing and results in mammalian target of rapamyAP-1 regulates cyclin D1 and c-MYC transcription in an AKT-dependent manner in response to mTOR inhibition: role of AIP4/Itch-mediated JUNB degradationHeterogeneous nuclear ribonucleoprotein A1 is a novel cellular target of atrial natriuretic peptide signaling in renal epithelial cells.Poly(ADP-ribose) controls DE-cadherin-dependent stem cell maintenance and oocyte localization.Phosphorylation of the Hippo Pathway Component AMOTL2 by the mTORC2 Kinase Promotes YAP Signaling, Resulting in Enhanced Glioblastoma Growth and Invasiveness.Heterogeneous nuclear ribonucleoprotein A1 post-transcriptionally regulates Drp1 expression in neuroblastoma cellsThe soy isoflavone equol may increase cancer malignancy via up-regulation of eukaryotic protein synthesis initiation factor eIF4GInhibition of Mitogen-activated Protein Kinase (MAPK)-interacting Kinase (MNK) Preferentially Affects Translation of mRNAs Containing Both a 5'-Terminal Cap and Hairpin.Mechanistic Target of Rapamycin (mTOR) Inhibition Synergizes with Reduced Internal Ribosome Entry Site (IRES)-mediated Translation of Cyclin D1 and c-MYC mRNAs to Treat Glioblastoma.RNA-binding proteins impacting on internal initiation of translation.Human immunodeficiency virus type 1 (HIV-1) induces the cytoplasmic retention of heterogeneous nuclear ribonucleoprotein A1 by disrupting nuclear import: implications for HIV-1 gene expression.Translation initiation: a critical signalling node in cancer.Oncogenic AKTivation of translation as a therapeutic target.mTOR, metabolism, and the regulation of T-cell differentiation and function.hnRNP A1: the Swiss army knife of gene expression.Deregulation of splicing factors and breast cancer development.Therapeutic potential of targeting IRES-dependent c-myc translation in multiple myeloma cells during ER stress.hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling.microRNA-18a induces apoptosis in colon cancer cells via the autophagolysosomal degradation of oncogenic heterogeneous nuclear ribonucleoprotein A1.MNK kinases facilitate c-myc IRES activity in rapamycin-treated multiple myeloma cellsInhibition of SAPK2/p38 enhances sensitivity to mTORC1 inhibition by blocking IRES-mediated translation initiation in glioblastoma.Upregulated c-myc expression in multiple myeloma by internal ribosome entry results from increased interactions with and expression of PTB-1 and YB-1.Regulation of D-cyclin translation inhibition in myeloma cells treated with mammalian target of rapamycin inhibitors: rationale for combined treatment with extracellular signal-regulated kinase inhibitors and rapamycin.microRNA-451-modulated hnRNP A1 takes a part in granulocytic differentiation regulation and acute myeloid leukemia.mTORC2/AKT/HSF1/HuR constitute a feed-forward loop regulating Rictor expression and tumor growth in glioblastoma.SMN regulation in SMA and in response to stress: new paradigms and therapeutic possibilities.
P2860
Q26770568-BCA26594-2977-4191-B385-EEE5F5150B3AQ27009883-2FBD1A19-1994-41D8-8774-49CA3AD4D475Q28297381-91587166-201C-4648-ACD2-18706F31DB55Q28547716-DD9F1021-8B3F-4E74-B137-AB55E9172099Q28573015-2ED5C1BE-3A30-408E-9AAB-438E2F80F2ADQ28573820-5CE078C9-81F5-45F6-A259-6B9FC5099DDFQ33378958-3479CAA9-E5D5-42C1-8A63-24A770B04EC6Q33635946-6F8EE8F4-3772-4BD2-AF65-0DF41CB2AA59Q33843662-8B9BCD95-AC04-405B-B1BF-FD42BE5A0296Q34127271-ADA04415-DFC9-4CFA-BEDC-5813762496BFQ34380167-20C1B988-BEB9-430A-8B0F-CD8B8962D137Q34452704-DA17E19C-1EE6-4F4B-A9F7-F08ABF9DBD8FQ34624747-C9E29956-83F9-4E00-B909-5C75A49FB658Q34883541-B78ADA5D-EC4A-4C49-8783-0691FD9F30FDQ34963710-2F346155-E191-4607-9BAD-EDD31F72CE75Q35018011-57E4BFA2-220E-453F-8321-EE14D5611C33Q35783161-9A0A7800-81FE-4FB1-B22E-BF227BDCC452Q35872182-866E9432-B7A5-4652-B566-1D86B37F15E8Q35925760-05D2E42B-82FC-47E8-AF4B-421EA497835CQ36306882-597A1DAA-E510-47BA-A7C9-0C9C142CF4F0Q36451858-1738A86C-EB85-40A8-A4F3-0501095266F3Q36573991-96738774-8577-4CD4-8D96-1534B01A25D5Q37065737-F6BB2E02-97F8-4ACA-A58A-129F572D4739Q37375354-FA8D9D64-C49F-4FFB-B2E7-7B0013663305Q37431534-169788B2-646C-41BC-A498-960041A7407CQ37586472-8334292E-649E-42B6-94DD-CC300585A5B3Q37902875-A9EB846C-317E-4F4C-B1DF-F95F046572ACQ38034265-246DA733-8EE9-4D01-BE13-DD28448EF6A3Q38142712-0F2D60CB-F756-4A17-A3B7-7A8ECF2FF209Q38463397-B9DBBD3B-C1D5-4213-BB7A-AFE7D2B0DD7EQ38876640-B585403A-544D-46CA-99DD-426C5E3F5F7BQ38946989-1705ACF0-4A9C-4A4C-8BAC-A951607844C6Q39069330-1A58C34E-B619-48AA-B6A9-AF624EDB70A8Q39389252-FF845CDC-5516-46F8-B2DF-63F2E6EEE31AQ39475114-C7D50DE0-33A7-48C0-A0BA-AC58781993E4Q39733957-74CB5AAE-6FD3-49EC-AA08-32C48C362976Q39896259-5DB4EDC6-7891-4579-9378-D50E8AD43E22Q41548277-7D55579B-8A9F-4132-B700-73A33A68885EQ45982916-C6E8DC8F-6A62-4AD5-A1C4-9FA128181FD8Q47885235-6718F6E4-374A-4332-AC0B-C85E7376AF8F
P2860
Heterogeneous nuclear ribonucleoprotein A1 regulates cyclin D1 and c-myc internal ribosome entry site function through Akt signaling.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Heterogeneous nuclear ribonucl ...... unction through Akt signaling.
@en
type
label
Heterogeneous nuclear ribonucl ...... unction through Akt signaling.
@en
prefLabel
Heterogeneous nuclear ribonucl ...... unction through Akt signaling.
@en
P2093
P2860
P356
P1476
Heterogeneous nuclear ribonucl ...... unction through Akt signaling.
@en
P2093
Alan Lichtenstein
Andrew Bernath
Janine Masri
Jheralyn Martin
Joseph Gera
P2860
P304
23274-23287
P356
10.1074/JBC.M801185200
P407
P577
2008-06-18T00:00:00Z