Inhibition of SAPK2/p38 enhances sensitivity to mTORC1 inhibition by blocking IRES-mediated translation initiation in glioblastoma.

Inhibition of SAPK2/p38 enhances sensitivity to mTORC1 inhibition by blocking IRES-mediated translation initiation in glioblastoma.

Item
http://www.wikidata.org/entity/Q39475114
Lifespan extension in a semelparous chordate occurs via developmental growth arrest just prior to meiotic entryMechanisms of protein synthesis activation following exercise: new pieces to the increasingly complex puzzle.Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma.mTORC2 modulates feedback regulation of p38 MAPK activity via DUSP10/MKP5 to confer differential responses to PP242 in glioblastomaPhosphorylation of the Hippo Pathway Component AMOTL2 by the mTORC2 Kinase Promotes YAP Signaling, Resulting in Enhanced Glioblastoma Growth and Invasiveness.IRES-dependent translation of egr2 is induced under inflammatory conditions.NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200Mechanistic Target of Rapamycin (mTOR) Inhibition Synergizes with Reduced Internal Ribosome Entry Site (IRES)-mediated Translation of Cyclin D1 and c-MYC mRNAs to Treat Glioblastoma.RNA-binding proteins impacting on internal initiation of translation.MicroRNA-124 expression counteracts pro-survival stress responses in glioblastoma.mTORC2/AKT/HSF1/HuR constitute a feed-forward loop regulating Rictor expression and tumor growth in glioblastoma.
P2860

Inhibition of SAPK2/p38 enhances sensitivity to mTORC1 inhibition by blocking IRES-mediated translation initiation in glioblastoma.

Item
http://www.wikidata.org/entity/Q39475114
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Inhibition of SAPK2/p38 enhanc ...... on initiation in glioblastoma.
@en
Inhibition of SAPK2/p38 enhanc ...... on initiation in glioblastoma.
@nl
type
label
Inhibition of SAPK2/p38 enhanc ...... on initiation in glioblastoma.
@en
Inhibition of SAPK2/p38 enhanc ...... on initiation in glioblastoma.
@nl
prefLabel
Inhibition of SAPK2/p38 enhanc ...... on initiation in glioblastoma.
@en
Inhibition of SAPK2/p38 enhanc ...... on initiation in glioblastoma.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Inhibition of SAPK2/p38 enhanc ...... on initiation in glioblastoma.
@en
P2093
P2860
P304
P31
P356
10.1158/1535-7163.MCT-11-0478
P433
P478
P577
P5875
P698
P932