about
A novel c-Myc-responsive gene, JPO1, participates in neoplastic transformationInterference with the expression of a novel human polycomb protein, hPc2, results in cellular transformation and apoptosisRING1 interacts with multiple Polycomb-group proteins and displays tumorigenic activityExpression, regulation, and chromosomal localization of the Max geneAlternative processing of RNA transcribed from NMYCIdentification of a large Myc-binding protein that contains RCC1-like repeatsNonviral oncogenic antigens and the inflammatory signals driving early cancer development as targets for cancer immunopreventionSynergistic action of the microRNA-17 polycistron and Myc in aggressive cancer developmentNegative control of the Myc protein by the stress-responsive kinase Pak2Enhanced RNA polymerase III-dependent transcription is required for oncogenic transformationMulti-factor data normalization enables the detection of copy number aberrations in amplicon sequencing data.N-myc transgene promotes B lymphoid proliferation, elicits lymphomas and reveals cross-regulation with c-myc.Myc-mediated transformation: the repression connection.Sustained expression of the human protooncogene MYCN rescues rat embryo cells from senescence.Tumors induced in mice by direct inoculation of plasmid DNA expressing both activated H-ras and c-myc.Deregulated expression of human c-jun transforms primary rat embryo cells in cooperation with an activated c-Ha-ras gene and transforms rat-1a cells as a single gene.Targeted expression of MYCN causes neuroblastoma in transgenic mice.c-Myc overexpression uncouples DNA replication from mitosis.HMG-I/Y, a new c-Myc target gene and potential oncogeneInduction of cell cycle progression and acceleration of apoptosis are two separable functions of c-Myc: transrepression correlates with acceleration of apoptosisSynthetic lethal screen identifies NF-κB as a target for combination therapy with topotecan for patients with neuroblastomaA mouse strain defective in both T cells and NK cells has enhanced sensitivity to tumor induction by plasmid DNA expressing both activated H-Ras and c-MycDifferential gene expression in SV40-mediated immortalization of human fibroblasts.Human neuroblastoma cell lines as models for the in vitro study of neoplastic and neuronal cell differentiationAberrant expression and function of gap junctions during carcinogenesis.An in vivo function for the transforming Myc protein: elicitation of the angiogenic phenotype.Mxi1 and mxi1-0 antagonize N-myc function and independently mediate apoptosis in neuroblastomaMolecular biology in the diagnosis and prognosis of solid and lymphoid tumors.Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line.MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunitsHigh frequency of myelomonocytic tumors in aging E mu L-myc transgenic mice.c-Myc transactivation of LDH-A: implications for tumor metabolism and growth.Transient excess of MYC activity can elicit genomic instability and tumorigenesis.Amplification of the MYCN oncogene and deletion of putative tumour suppressor gene in human neuroblastomas.Neuroblastoma--clinical applications of molecular parameters.Myc-mediated apoptosis is blocked by ectopic expression of Bcl-2Differential regulation of the N-myc gene in transfected cells and transgenic mice.Excision of N-myc from chromosome 2 in human neuroblastoma cells containing amplified N-myc sequences.L-myc cooperates with ras to transform primary rat embryo fibroblasts.Altered chromosome 6 in immortal human fibroblasts
P2860
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P2860
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
Neoplastic transformation by the human gene N-myc
@en
type
label
Neoplastic transformation by the human gene N-myc
@en
prefLabel
Neoplastic transformation by the human gene N-myc
@en
P2093
P2860
P356
P1476
Neoplastic transformation by the human gene N-myc
@en
P2093
P2860
P304
P356
10.1128/MCB.7.5.1638
P407
P577
1987-05-01T00:00:00Z