Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice
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Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancersAngiogenesis inhibitor vasohibin-1 enhances stress resistance of endothelial cells via induction of SOD2 and SIRT1Histone Deacetylases and Cardiometabolic DiseasesThe role of oxidative stress and inflammation in cardiovascular agingDNA damage and repair in atherosclerosis: current insights and future perspectivesProatherogenic abnormalities of lipid metabolism in SirT1 transgenic mice are mediated through Creb deacetylationGinkgolide B reduces LOX-1 expression by inhibiting Akt phosphorylation and increasing Sirt1 expression in oxidized LDL-stimulated human umbilical vein endothelial cellsSIRT1 inhibits TNF-α-induced apoptosis of vascular adventitial fibroblasts partly through the deacetylation of FoxO1Mammalian sirtuins: biological insights and disease relevanceMolecular mechanism of endothelial and vascular aging: implications for cardiovascular disease.SIRT1 mediates the protective function of Nkx2.5 during stress in cardiomyocytes.Emergent cardiovascular risk factors in the very elderly.Activation of SIRT1 by resveratrol induces KLF2 expression conferring an endothelial vasoprotective phenotype.Mitochondria, endothelial cell function, and vascular diseases.Crosstalk between the DNA damage response, histone modifications and neovascularisation.Long-term high-fat consumption leads to downregulation of Akt phosphorylation of eNOS at Ser1177 and upregulation of Sirtuin-1 expression in rat cavernous tissue.Anti-atherogenic properties of resveratrol: 4-week resveratrol administration associated with serum concentrations of SIRT1, adiponectin, S100A8/A9 and VSMCs contractility in a rat model.AMPK and SIRT1: a long-standing partnership?Early apoptotic vascular signaling is determined by Sirt1 through nuclear shuttling, forkhead trafficking, bad, and mitochondrial caspase activation.Effects of aging on angiogenesis.Shear stress, SIRT1, and vascular homeostasis.Short-term calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress.Quercetin is a potent anti-atherosclerotic compound by activation of SIRT1 signaling under oxLDL stimulation.Emphysema is associated with increased inflammation in lungs of atherosclerosis-prone mice by cigarette smoke: implications in comorbidities of COPD.SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice.SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesisAnti-inflammatory therapies for cardiovascular diseaseMechanisms of vascular aging: new perspectives.Sirt1 inhibits resistin expression in aortic stenosisEndothelial nitric oxide synthase transgenic models of endothelial dysfunctionSIRT1 regulates endothelial Notch signaling in lung cancer.Interferon regulatory factor 9 is critical for neointima formation following vascular injuryEndurance exercise training inhibits neointimal formation via enhancement of FOXOs expression in balloon-induced atherosclerosis rat model.Peripheral blood monocyte Sirt1 expression is reduced in patients with coronary artery disease.The SIRT1 activator SRT1720 reverses vascular endothelial dysfunction, excessive superoxide production, and inflammation with aging in miceRedox factor-1 activates endothelial SIRTUIN1 through reduction of conserved cysteine sulfhydryls in its deacetylase domain.Activation of sterol regulatory element binding protein and NLRP3 inflammasome in atherosclerotic lesion development in diabetic pigs.The Sirt1 activator SRT3025 provides atheroprotection in Apoe-/- mice by reducing hepatic Pcsk9 secretion and enhancing Ldlr expression.The endotoxin/toll-like receptor-4 axis mediates gut microvascular dysfunction associated with post-prandial lipidemia.SIRT1-mediated epigenetic downregulation of plasminogen activator inhibitor-1 prevents vascular endothelial replicative senescence
P2860
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P2860
Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Endothelium-specific overexpre ...... polipoprotein E-deficient mice
@en
type
label
Endothelium-specific overexpre ...... polipoprotein E-deficient mice
@en
prefLabel
Endothelium-specific overexpre ...... polipoprotein E-deficient mice
@en
P2093
P2860
P921
P356
P1476
Endothelium-specific overexpre ...... polipoprotein E-deficient mice
@en
P2093
Chih-Chuan Liang
De-Pei Liu
Hou-Zao Chen
Qing-Jun Zhang
Shuang Zhou
Yu-Sheng Wei
P2860
P304
P356
10.1093/CVR/CVN224
P577
2008-08-09T00:00:00Z