Plasma membrane localization signals in the light chain of botulinum neurotoxin. - Wikidata - wikimedia - TriplyDB

Plasma membrane localization signals in the light chain of botulinum neurotoxin.

Plasma membrane localization signals in the light chain of botulinum neurotoxin.

http://www.wikidata.org/entity/Q36854737

about

Emerging opportunities for serotypes of botulinum neurotoxins Botulinum neurotoxin serotype A specific cell-based potency assay to replace the mouse bioassay A V H H that neutralizes the zinc metalloproteinase activity of botulinum neurotoxin type A Camelid single domain antibodies (VHHs) as neuronal cell intrabody binding agents and inhibitors of Clostridium botulinum neurotoxin (BoNT) proteases Targeting botulinum neurotoxin persistence by the ubiquitin-proteasome system.A yeast assay probes the interaction between botulinum neurotoxin serotype B and its SNARE substrate.A dileucine in the protease of botulinum toxin A underlies its long-lived neuroparalysis: transfer of longevity to a novel potential therapeutic.Association of botulinum neurotoxin serotype A light chain with plasma membrane-bound SNAP-25 Drug Insight: biological effects of botulinum toxin A in the lower urinary tract.Persistence of botulinum neurotoxin a subtypes 1-5 in primary rat spinal cord cells The zinc-dependent protease activity of the botulinum neurotoxins Towards new uses of botulinum toxin as a novel therapeutic tool The analgesic potential of clostridial neurotoxin derivatives.Clinical uses of botulinum neurotoxins: current indications, limitations and future developments Activity-dependent phosphorylation of Ser187 is required for SNAP-25-negative modulation of neuronal voltage-gated calcium channels.Botulinum neurotoxin structure, engineering, and novel cellular trafficking and targeting.From GFP to β-lactamase: advancing intact cell imaging for toxins and effectors.The structure and mode of action of different botulinum toxins.Crystal structure of botulinum neurotoxin type G light chain: serotype divergence in substrate recognition.Septins: Regulators of Protein Stability.Using fluorescent sensors to detect botulinum neurotoxin activity in vitro and in living cells.Clostridial toxins.Bacterial toxins and the nervous system: neurotoxins and multipotential toxins interacting with neuronal cells.The blockade of the neurotransmitter release apparatus by botulinum neurotoxins.Unexpected transcellular protein crossover occurs during canonical DNA transfection Recruitment of septin cytoskeletal proteins by botulinum toxin A protease determines its remarkable stability.Botulinum Neurotoxins: Biology, Pharmacology, and Toxicology.Development of a Cell-Based Functional Assay for the Detection of Clostridium botulinum Neurotoxin Types A and E.Novel therapeutics based on recombinant botulinum neurotoxins to normalize the release of transmitters and pain mediators.Recombinant derivatives of botulinum neurotoxin A engineered for trafficking studies and neuronal delivery.Deubiquitinating enzyme VCIP135 dictates the duration of botulinum neurotoxin type A intoxication.Persistence of Botulinum neurotoxin inactivation of nerve function.Independent evolution of neurotoxin and flagellar genetic loci in proteolytic Clostridium botulinum.Neuronal entry and high neurotoxicity of botulinum neurotoxin A require its N-terminal binding sub-domain A Highly Specific Monoclonal Antibody for Botulinum Neurotoxin Type A-Cleaved SNAP25.A phosphatidylserine-binding site in the cytosolic fragment of Clostridium sordellii lethal toxin facilitates glucosylation of membrane-bound Rac and is required for cytotoxicity.Molecular architecture of botulinum neurotoxin E revealed by single particle electron microscopy.The Light Chain Defines the Duration of Action of Botulinum Toxin Serotype A Subtypes.

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Plasma membrane localization signals in the light chain of botulinum neurotoxin.

http://www.wikidata.org/entity/Q36854737

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2004年论文

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name

Plasma membrane localization signals in the light chain of botulinum neurotoxin.

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Plasma membrane localization signals in the light chain of botulinum neurotoxin.

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Plasma membrane localization signals in the light chain of botulinum neurotoxin.

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PNAS.0400229101

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Proceedings of the National Academy of Sciences of the United States of America

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Plasma membrane localization signals in the light chain of botulinum neurotoxin.

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Ester Fernández-Salas

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Helen Ho

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Joanne Wang

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Joseph Francis

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Joseph V Ordas

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K Roger Aoki

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Lance E Steward

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Marcella A Gilmore

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Patton E Garay

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Sarah W Sun

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P2860

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

The N-end rule: functions, mysteries, uses

Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity

Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B

Crystal structure of botulinum neurotoxin type A and implications for toxicity

A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains

Snares and Munc18 in synaptic vesicle fusion

The residues Leu(Ile)475-Ile(Leu, Val, Ala)476, contained in the extended carboxyl cytoplasmic tail, are critical for targeting of the resident lysosomal membrane protein LIMP II to lysosomes

A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor

A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4

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3208-3213

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scholarly article

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10.1073/PNAS.0400229101

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9

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101

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2004-02-24T00:00:00Z

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14982988

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