Loss of AKAP150 perturbs distinct neuronal processes in mice.
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Control of PKA stability and signalling by the RING ligase praja2Cross-talk and regulation between glutamate and GABAB receptorsAKAP13 Rho-GEF and PKD-binding domain deficient mice develop normally but have an abnormal response to β-adrenergic-induced cardiac hypertrophyM-current preservation contributes to anticonvulsant effects of valproic acid.Regulation of fear extinction versus other affective behaviors by discrete cortical scaffolding complexes associated with NR2B and PKA signalingBalanced interactions of calcineurin with AKAP79 regulate Ca2+–calcineurin–NFAT signalingRegulation of the phosphatase PP2B by protein-protein interactionsSignalling scaffolds and local organization of cellular behaviourNetworking with AKAPs: context-dependent regulation of anchored enzymesAnchored phosphatases modulate glucose homeostasisAKAP79/150 interacts with AC8 and regulates Ca2+-dependent cAMP synthesis in pancreatic and neuronal systemsRegulation of postsynaptic structure and function by an A-kinase anchoring protein-membrane-associated guanylate kinase scaffolding complexSubcellular dynamics of type II PKA in neuronsCa2+/calmodulin-dependent protein kinase II binds to and phosphorylates a specific SAP97 splice variant to disrupt association with AKAP79/150 and modulate alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptor (AMPAR) actiDecreased expression of A-kinase anchoring protein 150 in GT1 neurons decreases neuron excitability and frequency of intrinsic gonadotropin-releasing hormone pulses.Ca2+/calmodulin disrupts AKAP79/150 interactions with KCNQ (M-Type) K+ channelsAKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension.Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice.A-Kinase Anchoring Protein 79/150 Scaffolds Transient Receptor Potential A 1 Phosphorylation and Sensitization by Metabotropic Glutamate Receptor Activation.AKAP79 interacts with multiple adenylyl cyclase (AC) isoforms and scaffolds AC5 and -6 to alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) receptors.Colocalization of protein kinase A with adenylyl cyclase enhances protein kinase A activity during induction of long-lasting long-term-potentiationA presynaptic role for PKA in synaptic tagging and memory.A calcineurin/AKAP complex is required for NMDA receptor-dependent long-term depression.Organizing signal transduction through A-kinase anchoring proteins (AKAPs)AKAP79/150 impacts intrinsic excitability of hippocampal neurons through phospho-regulation of A-type K+ channel trafficking.Effects of AKAP5 Pro100Leu genotype on working memory for emotional stimuli.PP2B/calcineurin-mediated desensitization of TRPV1 does not require AKAP150.Architecture and dynamics of an A-kinase anchoring protein 79 (AKAP79) signaling complexA-kinase anchoring protein 150 mediates transient receptor potential family V type 1 sensitivity to phosphatidylinositol-4,5-bisphosphateA kinase anchor protein 150 (AKAP150)-associated protein kinase A limits dendritic spine density.AKAPs: the architectural underpinnings of local cAMP signaling.A Potential Role for a Genetic Variation of AKAP5 in Human Aggression and Anger ControlA-kinase Anchoring Protein 79/150 Recruits Protein Kinase C to Phosphorylate Roundabout Receptors.PKA-type I selective constrained peptide disruptors of AKAP complexesCurcumin Protects Neurons from Glutamate-Induced Excitotoxicity by Membrane Anchored AKAP79-PKA Interaction NetworkProtein Kinase A Opposes the Phosphorylation-dependent Recruitment of Glycogen Synthase Kinase 3β to A-kinase Anchoring Protein 220Palmitoylation of A-kinase anchoring protein 79/150 regulates dendritic endosomal targeting and synaptic plasticity mechanisms.A-kinase anchoring proteins as potential drug targets.Coordination of Protein Phosphorylation and Dephosphorylation in Synaptic PlasticityAKAP150-anchored calcineurin regulates synaptic plasticity by limiting synaptic incorporation of Ca2+-permeable AMPA receptors.
P2860
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P2860
Loss of AKAP150 perturbs distinct neuronal processes in mice.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Loss of AKAP150 perturbs distinct neuronal processes in mice.
@en
type
label
Loss of AKAP150 perturbs distinct neuronal processes in mice.
@en
prefLabel
Loss of AKAP150 perturbs distinct neuronal processes in mice.
@en
P2093
P2860
P356
P1476
Loss of AKAP150 perturbs distinct neuronal processes in mice.
@en
P2093
Brian J Tunquist
Eric S Guire
Fang Zhang
Jacob Raber
John D Scott
Karin Mullendorff
Lorene K Langeberg
Naoto Hoshi
P2860
P304
12557-12562
P356
10.1073/PNAS.0805922105
P407
P577
2008-08-18T00:00:00Z