Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis.
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Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesisA new member of the 4-methylideneimidazole-5-one-containing aminomutase family from the enediyne kedarcidin biosynthetic pathwayPolyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynesStructural characterization of CalO2: A putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathwayStructure and Catalytic Mechanism of the Thioesterase CalE7 in Enediyne BiosynthesisMolecular Basis of Substrate Promiscuity for the SAM-Dependent O -Methyltransferase NcsB1, Involved in the Biosynthesis of the Enediyne Antitumor Antibiotic NeocarzinostatinProbing the active site of MIO-dependent aminomutases, key catalysts in the biosynthesis of β-amino acids incorporated in secondary metabolitesStructural characterization of CalO1: a putative orsellinic acid methyltransferase in the calicheamicin-biosynthetic pathwayCrystal Structure of the Acyltransferase Domain of the Iterative Polyketide Synthase in Enediyne BiosynthesisThe crystal structure of BlmI as a model for nonribosomal peptide synthetase peptidyl carrier proteinsAncient horizontal gene transfer from bacteria enhances biosynthetic capabilities of fungiStrain Prioritization and Genome Mining for Enediyne Natural ProductsInsights into 6-Methylsalicylic Acid Bio-assembly by Using Chemical ProbesCrystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus.Role of sgcR3 in positive regulation of enediyne antibiotic C-1027 production of Streptomyces globisporus C-1027Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.Genome based analysis of type-I polyketide synthase and nonribosomal peptide synthetase gene clusters in seven strains of five representative Nocardia speciesStructural and bioinformatic characterization of an Acinetobacter baumannii type II carrier protein.Cyclization of aromatic polyketides from bacteria and fungiCharacterization of the calicheamicin orsellinate C2-O-methyltransferase CalO6.Natural products version 2.0: connecting genes to molecules.Enediyne antitumor antibiotic maduropeptin biosynthesis featuring a C-methyltransferase that acts on a CoA-tethered aromatic substrate.Complete genome sequence of Saccharothrix espanaensis DSM 44229(T) and comparison to the other completely sequenced Pseudonocardiaceae.Comparative analysis of the biosynthetic gene clusters and pathways for three structurally related antitumor antibiotics: bleomycin, tallysomycin, and zorbamycin.Biosynthesis of fosfazinomycin is a convergent process.Biosynthesis of enediyne antitumor antibioticsEnediyne polyketide synthases stereoselectively reduce the β-ketoacyl intermediates to β-D-hydroxyacyl intermediates in enediyne core biosynthesis.Biosynthetic origin and mechanism of formation of the aminoribosyl moiety of peptidyl nucleoside antibiotics.Enediynes: Exploration of microbial genomics to discover new anticancer drug leads.Genome neighborhood network reveals insights into enediyne biosynthesis and facilitates prediction and prioritization for discovery.Enzymatic chemistry of cyclopropane, epoxide, and aziridine biosynthesis.Insights into 6-Methylsalicylic Acid Bio-assembly by Using Chemical Probes.Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027Structural Characterization of CalS8, a TDP-α-D-Glucose Dehydrogenase Involved in Calicheamicin Aminodideoxypentose BiosynthesisBiosynthesis and genomic analysis of medium-chain hydrocarbon production by the endophytic fungal isolate Nigrograna mackinnonii E5202H.A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis.Increasing carbohydrate diversity via amine oxidation: aminosugar, hydroxyaminosugar, nitrososugar, and nitrosugar biosynthesis in bacteriaA free-standing condensation enzyme catalyzing ester bond formation in C-1027 biosynthesis.Characterization of CalE10, the N-oxidase involved in calicheamicin hydroxyaminosugar formationPredictive model for epoxide hydrolase-generated stereochemistry in the biosynthesis of nine-membered enediyne antitumor antibiotics.
P2860
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P2860
Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Characterization of the maduro ...... igm for enediyne biosynthesis.
@en
type
label
Characterization of the maduro ...... igm for enediyne biosynthesis.
@en
prefLabel
Characterization of the maduro ...... igm for enediyne biosynthesis.
@en
P2093
P2860
P356
P1476
Characterization of the maduro ...... igm for enediyne biosynthesis.
@en
P2093
Evelyn Wendt-Pienkowski
Steven G Van Lanen
Tae-Jin Oh
P2860
P304
13082-13094
P356
10.1021/JA073275O
P407
P577
2007-10-06T00:00:00Z