Universal strategies in research and drug discovery based on protein-fragment complementation assays.
about
Control of PKA stability and signalling by the RING ligase praja2Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cellsPhospho-tyrosine dependent protein-protein interaction networkA molecularly engineered split reporter for imaging protein-protein interactions with positron emission tomographyThe chemical biology of protein phosphorylationTechniques for the Analysis of Protein-Protein Interactions in VivoNature's recipe for splitting inteinsHigh-sensitivity real-time imaging of dual protein-protein interactions in living subjects using multicolor luciferasesSplit-cre complementation indicates coincident activity of different genes in vivoStructural and Thermodynamic Analysis of a Conformationally Strained Circular Permutant of Barnase †Structural Switch of Lysyl-tRNA Synthetase between Translation and TranscriptionSystematic Protein-Protein Interaction Analysis Reveals Intersubcomplex Contacts in the Nuclear Pore Complex.Cell-Based Assay Design for High-Content Screening of Drug CandidatesAn infrared reporter to detect spatiotemporal dynamics of protein-protein interactionsIn vivo continuous directed evolutionA versatile platform to analyze low-affinity and transient protein-protein interactions in living cells in real timeA split horseradish peroxidase for the detection of intercellular protein-protein interactions and sensitive visualization of synapsesFunctional assembly of protein fragments induced by spatial confinementMatched Peptides: Tuning Matched Molecular Pair Analysis for Biopharmaceutical ApplicationsBeta-barrel scaffold of fluorescent proteins: folding, stability and role in chromophore formation.Molecular interaction networks in the analyses of sequence variation and proteomics data.A coiled-coil enabled split-luciferase three-hybrid system: applied toward profiling inhibitors of protein kinases.A novel genetic screen implicates Elm1 in the inactivation of the yeast transcription factor SBF.Identification of ERGIC-53 as an intracellular transport receptor of alpha1-antitrypsin.Molecular imaging of phosphorylation events for drug developmentRandom dissection to select for protein split sites and its application in protein fragment complementationRapid modification of proteins using a rapamycin-inducible tobacco etch virus protease systemInterplay of PKA and Rac: fine-tuning of Rac localization and signaling.Characterization and optimization of a novel protein-protein interaction biosensor high-content screening assay to identify disruptors of the interactions between p53 and hDM2.Bimolecular fluorescence complementation: lighting up seven transmembrane domain receptor signalling networksA scalable double-barcode sequencing platform for characterization of dynamic protein-protein interactions.Assembling a protein-protein interaction map of the SSU processome from existing datasets.Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitorsCategorizing biases in high-confidence high-throughput protein-protein interaction data sets.An integrative omics strategy to assess the germ cell secretome and to decipher sertoli-germ cell crosstalk in the Mammalian testis.Novel molecular imaging platform for monitoring oncological kinases.A selection that reports on protein-protein interactions within a thermophilic bacterium.Split-protein systems: beyond binary protein-protein interactionsHigh-content positional biosensor screening assay for compounds to prevent or disrupt androgen receptor and transcriptional intermediary factor 2 protein-protein interactions.Dual-color click beetle luciferase heteroprotein fragment complementation assays.
P2860
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P2860
Universal strategies in research and drug discovery based on protein-fragment complementation assays.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Universal strategies in resear ...... agment complementation assays.
@en
type
label
Universal strategies in resear ...... agment complementation assays.
@en
prefLabel
Universal strategies in resear ...... agment complementation assays.
@en
P2093
P356
P1476
Universal strategies in resear ...... agment complementation assays.
@en
P2093
Eduard Stefan
Emily N Manderson
Ingrid Remy
Po Hien Ear
Stephen W Michnick
P2888
P304
P356
10.1038/NRD2311
P577
2007-07-01T00:00:00Z
P6179
1011258275