H-ras protein in a bilayer: interaction and structure perturbation
about
A novel switch region regulates H-ras membrane orientation and signal outputNovel allosteric sites on Ras for lead generationThe C-terminus of H-Ras as a target for the covalent binding of reactive compounds modulating Ras-dependent pathwaysThe Molecular Mechanism Underlying Recruitment and Insertion of Lipid-Anchored LC3 Protein into MembranesThe C-terminal sequence of RhoB directs protein degradation through an endo-lysosomal pathwayWater-membrane partition thermodynamics of an amphiphilic lipopeptide: an enthalpy-driven hydrophobic effect.The peptide hormone ghrelin binds to membrane-mimetics via its octanoyl chain and an adjacent phenylalanine.Identification of H-Ras-specific motif for the activation of invasive signaling program in human breast epithelial cells.Nonsteroidal anti-inflammatory drugs alter the spatiotemporal organization of Ras proteins on the plasma membrane.Ras trafficking, localization and compartmentalized signallingOverview of simulation studies on the enzymatic activity and conformational dynamics of the GTPase Ras.GTP Binding and Oncogenic Mutations May Attenuate Hypervariable Region (HVR)-Catalytic Domain Interactions in Small GTPase K-Ras4B, Exposing the Effector Binding Site.Formation and domain partitioning of H-ras peptide nanoclusters: effects of peptide concentration and lipid composition.The higher level of complexity of K-Ras4B activation at the membrane.Thermodynamics of peptide insertion and aggregation in a lipid bilayerThe Role of Signaling via Aqueous Pore Formation in Resistance Responses to Amphotericin BLessons from computer simulations of Ras proteins in solution and in membraneDeformation of a Two-domain Lipid Bilayer due to Asymmetric Insertion of Lipid-modified Ras Peptides.AMPK and Endothelial Nitric Oxide Synthase Signaling Regulates K-Ras Plasma Membrane Interactions via Cyclic GMP-Dependent Protein Kinase 2.Drugging Ras GTPase: a comprehensive mechanistic and signaling structural view.Staurosporines disrupt phosphatidylserine trafficking and mislocalize Ras proteins.Segregation of negatively charged phospholipids by the polycationic and farnesylated membrane anchor of Kras.Aggregation of lipid-anchored full-length H-Ras in lipid bilayers: simulations with the MARTINI force field.Similar membrane affinity of mono- and Di-S-acylated ras membrane anchors: a new twist in the role of protein lipidation.What drives the clustering of membrane-bound Ras?K-Ras4B Remains Monomeric on Membranes over a Wide Range of Surface Densities and Lipid Compositions.Lipid-Sorting Specificity Encoded in K-Ras Membrane Anchor Regulates Signal Output.The role of G-domain orientation and nucleotide state on the Ras isoform-specific membrane interaction
P2860
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P2860
H-ras protein in a bilayer: interaction and structure perturbation
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
H-ras protein in a bilayer: interaction and structure perturbation
@en
type
label
H-ras protein in a bilayer: interaction and structure perturbation
@en
prefLabel
H-ras protein in a bilayer: interaction and structure perturbation
@en
P2860
P356
P1476
H-ras protein in a bilayer: interaction and structure perturbation
@en
P2093
Alemayehu A Gorfe
Arneh Babakhani
P2860
P304
12280-12286
P356
10.1021/JA073949V
P407
P577
2007-09-19T00:00:00Z