Rolipram attenuates acute oligodendrocyte death in the adult rat ventrolateral funiculus following contusive cervical spinal cord injury.
about
The therapeutic profile of rolipram, PDE target and mechanism of action as a neuroprotectant following spinal cord injuryLipidic nanocapsule drug delivery: neuronal protection for cochlear implant optimizationDrug-eluting microfibrous patches for the local delivery of rolipram in spinal cord repairPhosphodiesterase Inhibitors as a Therapeutic Approach to Neuroprotection and Repair.PTEN inhibitor bisperoxovanadium protects oligodendrocytes and myelin and prevents neuronal atrophy in adult rats following cervical hemicontusive spinal cord injury.Dose and chemical modification considerations for continuous cyclic AMP analog delivery to the injured CNSEffects of dibutyryl cyclic-AMP on survival and neuronal differentiation of neural stem/progenitor cells transplanted into spinal cord injured rats.Current therapeutic strategies for inflammation following traumatic spinal cord injuryOligodendrocyte fate after spinal cord injury.A selective phosphodiesterase-4 inhibitor reduces leukocyte infiltration, oxidative processes, and tissue damage after spinal cord injury.Cyclic AMP is both a pro-apoptotic and anti-apoptotic second messengerProinflammatory cytokine regulation of cyclic AMP-phosphodiesterase 4 signaling in microglia in vitro and following CNS injury.Postinjury treatment with rolipram increases hemorrhage after traumatic brain injuryEffects of rolipram on adult rat oligodendrocytes and functional recovery after contusive cervical spinal cord injury.A review of published reports on neuroprotection in spinal cord injury.Inhibition of phosphodiesterase-4 promotes oligodendrocyte precursor cell differentiation and enhances CNS remyelination.Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model.Glial restricted precursor cell transplant with cyclic adenosine monophosphate improved some autonomic functions but resulted in a reduced graft size after spinal cord contusion injury in rats.Antioxidant Protection of NADPH-Depleted Oligodendrocyte Precursor Cells Is Dependent on Supply of Reduced Glutathione.Identification of cytosolic phosphodiesterases in the erythrocyte: a possible role for PDE5.Rolipram-Loaded Polymeric Micelle Nanoparticle Reduces Secondary Injury after Rat Compression Spinal Cord Injury.Inhibition of endogenous phosphodiesterase 7 promotes oligodendrocyte precursor differentiation and survival.Regenerative Strategies for the Central Nervous System
P2860
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P2860
Rolipram attenuates acute oligodendrocyte death in the adult rat ventrolateral funiculus following contusive cervical spinal cord injury.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Rolipram attenuates acute olig ...... e cervical spinal cord injury.
@en
type
label
Rolipram attenuates acute olig ...... e cervical spinal cord injury.
@en
prefLabel
Rolipram attenuates acute olig ...... e cervical spinal cord injury.
@en
P2093
P2860
P1433
P1476
Rolipram attenuates acute olig ...... e cervical spinal cord injury.
@en
P2093
Christopher M Whitaker
David S K Magnuson
Eric Beaumont
Michael J Wells
Stephen M Onifer
P2860
P304
P356
10.1016/J.NEULET.2008.03.087
P407
P577
2008-04-08T00:00:00Z