A new family of 10 murine ovalbumin serpins includes two homologs of proteinase inhibitor 8 and two homologs of the granzyme B inhibitor (proteinase inhibitor 9).
about
The plasminogen activator inhibitor-2 gene is not required for normal murine development or survivalSerpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systemsThe major human and mouse granzymes are structurally and functionally divergentSerine proteinase inhibitor 9 can be recognized by cytotoxic T lymphocytes of epithelial cancer patientsInflammasomes: caspase-1-activating platforms with critical roles in host defenseA natural genetic variant of granzyme B confers lethality to a common viral infectionRecognition of ADP-ribosylation factor 4-like by HLA-A2-restricted and tumor-reactive cytotoxic T lymphocytes from patients with brain tumors.A new intracellular serine protease inhibitor expressed in the rat pituitary gland complexes with granzyme B.Selective regulation of apoptosis: the cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathwayBlockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors.Memory CD8+ T cells protect dendritic cells from CTL killing.Serpinb9 (Spi6)-deficient mice are impaired in dendritic cell-mediated antigen cross-presentation.The domains of apoptosis: a genomics perspective.Intracellular serpins in haemopoietic and peripheral blood cells.Death by a thousand cuts: granzyme pathways of programmed cell deathPerforin deficiency and susceptibility to cancer.Perforin: structure, function, and role in human immunopathology.A colorimetric assay that specifically measures Granzyme B proteolytic activity: hydrolysis of Boc-Ala-Ala-Asp-S-BzlGranzyme B regulates antiviral CD8+ T cell responses.Serine protease inhibitor 6 is required to protect dendritic cells from the kiss of deathAccelerated skin wound healing in plasminogen activator inhibitor-1-deficient miceExpression of the serpin serine protease inhibitor 6 protects dendritic cells from cytotoxic T lymphocyte-induced apoptosis: differential modulation by T helper type 1 and type 2 cells.A Novel Serpin Regulatory Mechanism: SerpinB9 IS REVERSIBLY INHIBITED BY VICINAL DISULFIDE BOND FORMATION IN THE REACTIVE CENTER LOOPHematopoietic stem cell function and survival depend on c-Myc and N-Myc activityGranzyme C supports efficient CTL-mediated killing late in primary alloimmune responses.Intrahepatic lymphocyte expression of dipeptidyl peptidase I-processed granzyme B and perforin induces hepatocyte expression of serine proteinase inhibitor 6 (Serpinb9/SPI-6).The role of serpinb9/serine protease inhibitor 6 in preventing granzyme B-dependent hepatotoxicity.Serine protease inhibitor-6 differentially affects the survival of effector and memory alloreactive CD8-T cells.The role of serpins in vertebrate immunity.Serpins in T cell immunity.Serine protease inhibitors and cytotoxic T lymphocytes.Granzyme M: behind enemy lines.Identification of Serpinb6b as a species-specific mouse granzyme A inhibitor suggests functional divergence between human and mouse granzyme A.Mesenchymal stem cells express serine protease inhibitor to evade the host immune response.A novel domain in adenovirus L4-100K is required for stable binding and efficient inhibition of human granzyme B: possible interaction with a species-specific exosite.A pro-survival role for the intracellular granzyme B inhibitor Serpinb9 in natural killer cells during poxvirus infection.Cloning of pig serine proteinase inhibitor 9 and its use in protecting against apoptosis.Serpins prevent granzyme-induced death in a species-specific manner.Importance of the P4' residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop.Serine protease inhibitor 2A is a protective factor for memory T cell development.
P2860
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P2860
A new family of 10 murine ovalbumin serpins includes two homologs of proteinase inhibitor 8 and two homologs of the granzyme B inhibitor (proteinase inhibitor 9).
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
A new family of 10 murine oval ...... itor (proteinase inhibitor 9).
@en
type
label
A new family of 10 murine oval ...... itor (proteinase inhibitor 9).
@en
prefLabel
A new family of 10 murine oval ...... itor (proteinase inhibitor 9).
@en
P2093
P2860
P356
P1476
A new family of 10 murine oval ...... bitor (proteinase inhibitor 9)
@en
P2093
P2860
P304
15434-15441
P356
10.1074/JBC.272.24.15434
P407
P577
1997-06-01T00:00:00Z