Basis for design and development of platinum(IV) anticancer complexes.
about
Say No to DMSO: Dimethylsulfoxide Inactivates Cisplatin, Carboplatin, and Other Platinum ComplexesBeyond picomolar affinities: quantitative aspects of noncovalent and covalent binding of drugs to proteinsCytotoxic properties of a new organometallic platinum(II) complex and its gold(I) heterobimetallic derivativesIn situ imaging of metals in cells and tissuesInsights into the acid-base properties of Pt(IV)-diazidodiam(m)inedihyroxido complexes from multinuclear NMR spectroscopy.Synthesis, Characterization, and Interaction with Biomolecules of Platinum(II) Complexes with Shikimic Acid-Based Ligands.Reinterpretation of the vibrational spectroscopy of the medicinal bioinorganic synthon c,c,t-[Pt(NH3)2Cl2(OH)2].Polysilsesquioxane nanoparticles for targeted platin-based cancer chemotherapy by triggered releaseEpigenetic and antitumor effects of platinum(IV)-octanoato conjugates.Pt(IV) prodrugs designed to bind non-covalently to human serum albumin for drug deliverySynthesis and characterization of novel bis(carboxylato)dichloridobis(ethylamine)platinum(IV) complexes with higher cytotoxicity than cisplatinPhotocytotoxic trans-diam(m)ine platinum(IV) diazido complexes more potent than their cis isomers.Structure-based DNA-targeting strategies with small molecule ligands for drug discovery.Synthesis, characterization, and cytotoxicity of platinum(IV) carbamate complexesCopper-free click-chemistry platform to functionalize cisplatin prodrugs.A novel class of bis- and tris-chelate diam(m)inebis(dicarboxylato)platinum(IV) complexes as potential anticancer prodrugs.Comparative in vitro and in vivo pharmacological investigation of platinum(IV) complexes as novel anticancer drug candidates for oral application.Spectrum of cellular responses to pyriplatin, a monofunctional cationic antineoplastic platinum(II) compound, in human cancer cellsConjugation of cisplatin analogues and cyclooxygenase inhibitors to overcome cisplatin resistance.Modulation of Ligand Fluorescence by the Pt(II)/Pt(IV) Redox Couple.Comparison of the effects of the oral anticancer platinum(IV) complexes oxoplatin and metabolite cis-diammine-tetrachlorido-platinum(IV) on global gene expression of NCI-H526 cellsNanoparticle encapsulation of mitaplatin and the effect thereof on in vivo propertiesNew trends for metal complexes with anticancer activityResistance to chemotherapy in cancer: a complex and integrated cellular response.Oxidative Stress Induced by Pt(IV) Pro-drugs Based on the Cisplatin Scaffold and Indole Carboxylic Acids in Axial PositionNovel metals and metal complexes as platforms for cancer therapySynthesis and characterization of Pt(IV) fluorescein conjugates to investigate Pt(IV) intracellular transformationsMonofunctional and higher-valent platinum anticancer agents.Current applications and future potential for bioinorganic chemistry in the development of anticancer drugs.Synthetic methods for the preparation of platinum anticancer complexes.Inorganic nanoparticles in cancer therapy.Anticancer activity of metal complexes: involvement of redox processes.Targeted therapy vs. DNA-adduct formation-guided design: thoughts about the future of metal-based anticancer drugs.Targeting and delivery of platinum-based anticancer drugs.Functional block copolymer assemblies responsive to tumor and intracellular microenvironments for site-specific drug delivery and enhanced imaging performance.The use of X-ray absorption and synchrotron based micro-X-ray fluorescence spectroscopy to investigate anti-cancer metal compounds in vivo and in vitro.Metal complex interactions with DNA.A Photoactivatable Platinum(IV) Anticancer Complex Conjugated to the RNA Ligand Guanidinoneomycin.Polymeric biomaterials for the delivery of platinum-based anticancer drugs.RGD-mediated delivery of small-molecule drugs.
P2860
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P2860
Basis for design and development of platinum(IV) anticancer complexes.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Basis for design and development of platinum(IV) anticancer complexes.
@en
type
label
Basis for design and development of platinum(IV) anticancer complexes.
@en
prefLabel
Basis for design and development of platinum(IV) anticancer complexes.
@en
P2093
P356
P1476
Basis for design and development of platinum(IV) anticancer complexes.
@en
P2093
Howard R Mellor
Matthew D Hall
Richard Callaghan
Trevor W Hambley
P304
P356
10.1021/JM070280U
P407
P577
2007-06-28T00:00:00Z