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Resistance to chemotherapy in cancer: a complex and integrated cellular response.

Resistance to chemotherapy in cancer: a complex and integrated cellular response.

http://www.wikidata.org/entity/Q37079652

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Prediction of Cancer Drug Resistance and Implications for Personalized Medicine Peroxisome proliferator-activated receptors in regulation of cytochromes P450: new way to overcome multidrug resistance?NSC23925, identified in a high-throughput cell-based screen, reverses multidrug resistance Inherent and acquired resistance to paclitaxel in hepatocellular carcinoma: molecular events involved Reducing Both Pgp Overexpression and Drug Efflux with Anti-Cancer Gold-Paclitaxel Nanoconjugates Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments.Expression profile and specific network features of the apoptotic machinery explain relapse of acute myeloid leukemia after chemotherapy.Evaluation of bioactive sphingolipids in 4-HPR-resistant leukemia cells Optimization of the antitumor activity of sequence-specific pyrrolobenzodiazepine derivatives based on their affinity for ABC transporters.Defining new criteria for selection of cell-based intestinal models using publicly available databases.Overcoming drug resistance by regulating nuclear receptors.Vaccinia virus-mediated intra-tumoral expression of matrix metalloproteinase 9 enhances oncolysis of PC-3 xenograft tumors.Tumors that acquire resistance to low-dose metronomic cyclophosphamide retain sensitivity to maximum tolerated dose cyclophosphamide.Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells Current status of methods to assess cancer drug resistance.Tumor physiology and charge dynamics of anticancer drugs: implications for camptothecin-based drug development Development of a 'mouse and human cross-reactive' affinity-matured exosite inhibitory human antibody specific to TACE (ADAM17) for cancer immunotherapy.Biomolecular self-defense and futility of high-specificity therapeutic targeting.Enhanced expression of stem cell markers and drug resistance in sphere-forming non-small cell lung cancer cells.Expression of the copper transporters hCtr1, ATP7A and ATP7B is associated with the response to chemotherapy and survival time in patients with resected non-small cell lung cancer.Correlation between Gene Variants, Signaling Pathways, and Efficacy of Chemotherapy Drugs against Colon Cancers Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells.Role of metabolic modulator Bet-CA in altering mitochondrial hyperpolarization to suppress cancer associated angiogenesis and metastasis.Pharmacokinetics and tolerability of NSC23925b, a novel P-glycoprotein inhibitor: preclinical study in mice and rats.Drug Resistance Mechanisms in Non-Small Cell Lung Carcinoma.Inhibition of the multidrug resistance P-glycoprotein: time for a change of strategy?Drug therapy of cancer.Role of epigenomics in ovarian and endometrial cancers.Effect of pregnane X receptor expression on drug resistance in breast cancer.Integration of phytochemicals and phytotherapy into cancer precision medicine.miR-152 as a tumor suppressor microRNA: Target recognition and regulation in cancer.4H-Chromene-based anticancer agents towards multi-drug resistant HL60/MX2 human leukemia: SAR at the 4th and 6th positions.Down-Regulation of MRP1 Expression in C6/VP16 Cells by Chitosan-MRP1-siRNA Nanoparticles.Array of translational systems pharmacodynamic models of anti-cancer drugs.Hydrophobic ion pairing as a strategy to improve drug encapsulation into lipid nanocarriers for the cancer treatment.Quinoline carboxamide-type ABCG2 modulators: indole and quinoline moieties as anilide replacements.Retaining cytotoxic activity of anthrapyridone CO1 against multidrug resistant cells is related to the ability to induce concomitantly apoptosis and lysosomal death of leukaemia HL60/VINC and HL60/DOX cells.Can bevacizumab prolong survival for glioblastoma patients through multiple lines of therapy?Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2?The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia.

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Resistance to chemotherapy in cancer: a complex and integrated cellular response.

http://www.wikidata.org/entity/Q37079652

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 07 February 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Resistance to chemotherapy in cancer: a complex and integrated cellular response.

@en

Resistance to chemotherapy in cancer: a complex and integrated cellular response.

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type

label

Resistance to chemotherapy in cancer: a complex and integrated cellular response.

@en

Resistance to chemotherapy in cancer: a complex and integrated cellular response.

@nl

prefLabel

Resistance to chemotherapy in cancer: a complex and integrated cellular response.

@en

Resistance to chemotherapy in cancer: a complex and integrated cellular response.

@nl

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Resistance to chemotherapy in cancer: a complex and integrated cellular response.

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Howard R Mellor

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Richard Callaghan

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P2860

Cellular roles of dna topoisomerases: a molecular perspective

Human gamma-glutamyl hydrolase: cloning and characterization of the enzyme expressed in vitro

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

The binding conformation of Taxol in beta-tubulin: a model based on electron crystallographic density

Chemoresistance in human ovarian cancer: the role of apoptotic regulators

Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.

MGMT gene silencing and benefit from temozolomide in glioblastoma.

On the Origin of Cancer Cells

Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial

The Ki-67 protein: from the known and the unknown

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275-300

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10.1159/000115967

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