A new mechanism controlling kinetochore-microtubule interactions revealed by comparison of two dynein-targeting components: SPDL-1 and the Rod/Zwilch/Zw10 complex.
about
Caenorhabditis elegans cyclin B3 is required for multiple mitotic processes including alleviation of a spindle checkpoint-dependent block in anaphase chromosome segregationStructural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interactionMitotic control of kinetochore-associated dynein and spindle orientation by human SpindlyKinetochore-microtubule interactions: steps towards bi-orientationThe current view for the silencing of the spindle assembly checkpointReconstituting the kinetochore–microtubule interface: what, why, and howKinetochore function is controlled by a phospho-dependent coexpansion of inner and outer components.Kinetochore components are required for central spindle assembly.Regulators of the cytoplasmic dynein motorKinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerasesDynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunitLateral and End-On Kinetochore Attachments Are Coordinated to Achieve Bi-orientation in Drosophila OocytesA Centromere-Signaling Network Underlies the Coordination among Mitotic EventsThe Ndc80 complex: integrating the kinetochore's many movements.Kinetochores: orchestrating the chromosomal minuet.Dissection of CENP-C-directed centromere and kinetochore assemblySystematic analysis in Caenorhabditis elegans reveals that the spindle checkpoint is composed of two largely independent branches.Bub1 and Bub3 promote the conversion from monopolar to bipolar chromosome attachment independently of shugoshinSpindly/CCDC99 is required for efficient chromosome congression and mitotic checkpoint regulationA novel role of farnesylation in targeting a mitotic checkpoint protein, human Spindly, to kinetochoresDistinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint.Mechanism and regulation of cytoplasmic dyneinA tissue-specific protein purification approach in Caenorhabditis elegans identifies novel interaction partners of DLG-1/Discs large.MCAK is present at centromeres, midspindle and chiasmata and involved in silencing of the spindle assembly checkpoint in mammalian oocytes.Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cellsFinding the middle ground: how kinetochores power chromosome congression.The life and miracles of kinetochores.LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion.A kinetochore-independent mechanism drives anaphase chromosome separation during acentrosomal meiosis.NuMA-related LIN-5, ASPM-1, calmodulin and dynein promote meiotic spindle rotation independently of cortical LIN-5/GPR/Galpha.Polo-like kinase1 is required for recruitment of dynein to kinetochores during mitosisA maternal effect rough deal mutation suggests that multiple pathways regulate Drosophila RZZ kinetochore recruitment.CDK-1 inhibits meiotic spindle shortening and dynein-dependent spindle rotation in C. elegans.Caenorhabditis elegans EFA-6 limits microtubule growth at the cell cortex.Dynein-dependent processive chromosome motions promote homologous pairing in C. elegans meiosis.Identifying components of protein complexes in C. elegans using co-immunoprecipitation and mass spectrometry.Affinity purification of protein complexes in C. elegans.The KMN protein network--chief conductors of the kinetochore orchestraNew insights into the mechanism for chromosome alignment in metaphaseSystematic dissection of dynein regulators in mitosis
P2860
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P248
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P2860
A new mechanism controlling kinetochore-microtubule interactions revealed by comparison of two dynein-targeting components: SPDL-1 and the Rod/Zwilch/Zw10 complex.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A new mechanism controlling ki ...... d the Rod/Zwilch/Zw10 complex.
@en
type
label
A new mechanism controlling ki ...... d the Rod/Zwilch/Zw10 complex.
@en
prefLabel
A new mechanism controlling ki ...... d the Rod/Zwilch/Zw10 complex.
@en
P2093
P2860
P50
P921
P356
P1433
P1476
A new mechanism controlling ki ...... d the Rod/Zwilch/Zw10 complex.
@en
P2093
Anthony Essex
Arshad Desai
Bruce Bowerman
Fumio Motegi
Ian McLeod
Jia-Sheng Hu
John R Yates
Paul S Maddox
Sean M O'Rourke
P2860
P304
P356
10.1101/GAD.1687508
P5008
P577
2008-09-01T00:00:00Z