Effect of lysine at C-terminus of the Dmt-Tic opioid pharmacophore.
about
Current research on opioid receptor function.Endogenous opiates and behavior: 2006Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic.Evolution of the Bifunctional Lead μ Agonist / δ Antagonist Containing the Dmt-Tic Opioid PharmacophoreRole of 2',6'-dimethyl-l-tyrosine (Dmt) in some opioid lead compoundsEngineering endomorphin drugs: state of the art.Further studies on the effect of lysine at the C-terminus of the Dmt-Tic opioid pharmacophore.Role of benzimidazole (Bid) in the delta-opioid agonist pseudopeptide H-Dmt-Tic-NH-CH(2)-Bid (UFP-502)Inhibition of the development of morphine tolerance by a potent dual mu-delta-opioid antagonist, H-Dmt-Tic-Lys-NH-CH2-Ph.Synthesis of a potent and selective (18)F-labeled delta-opioid receptor antagonist derived from the Dmt-Tic pharmacophore for positron emission tomography imaging.Bifunctional [2',6'-dimethyl-L-tyrosine1]endomorphin-2 analogues substituted at position 3 with alkylated phenylalanine derivatives yield potent mixed mu-agonist/delta-antagonist and dual mu-agonist/delta-agonist opioid ligands.Orally administered H-Dmt-Tic-Lys-NH-CH2-Ph (MZ-2), a potent mu/delta-opioid receptor antagonist, regulates obese-related factors in mice.A DFT and semiempirical model-based study of opioid receptor affinity and selectivity in a group of molecules with a morphine structural coreSolid-phase synthetic strategy and bioevaluation of a labeled delta-opioid receptor ligand Dmt-Tic-Lys for in vivo imaging.
P2860
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P2860
Effect of lysine at C-terminus of the Dmt-Tic opioid pharmacophore.
description
2006 nî lūn-bûn
@nan
2006年の論文
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2006年論文
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2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
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2006年论文
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name
Effect of lysine at C-terminus of the Dmt-Tic opioid pharmacophore.
@en
type
label
Effect of lysine at C-terminus of the Dmt-Tic opioid pharmacophore.
@en
prefLabel
Effect of lysine at C-terminus of the Dmt-Tic opioid pharmacophore.
@en
P2093
P2860
P50
P356
P1476
Effect of lysine at C-terminus of the Dmt-Tic opioid pharmacophore
@en
P2093
Akihiro Ambo
Gianfranco Balboni
Lawrence H Lazarus
Margherita Zotti
Sharon D Bryant
Yunden Jinsmaa
Yusuke Sasaki
P2860
P304
P356
10.1021/JM060741W
P407
P577
2006-09-01T00:00:00Z