about
Role of thioredoxin reductase 1 and thioredoxin interacting protein in prognosis of breast cancerThe human selenoproteome: recent insights into functions and regulationRedox-directed cancer therapeutics: molecular mechanisms and opportunitiesHydrogen peroxide - production, fate and role in redox signaling of tumor cellsA conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma CareApoptosis of cholangiocytes modulated by thioredoxin of carcinogenic liver fluke.The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting proteinInteractions of gold-based drugs with proteins: the structure and stability of the adduct formed in the reaction between lysozyme and the cytotoxic gold(III) compound Auoxo3Thioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signalingMechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative diseasePegylated liposomal mitomycin C prodrug enhances tolerance of mitomycin C: a phase 1 study in advanced solid tumor patientsLoss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth.Cross-linking of thioredoxin reductase by the sulfur mustard analogue mechlorethamine (methylbis(2-chloroethyl)amine) in human lung epithelial cells and rat lung: selective inhibition of disulfide reduction but not redox cycling.PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells.Autophagy inhibition enhances vorinostat-induced apoptosis via ubiquitinated protein accumulation.A phase I trial of PX-12, a small-molecule inhibitor of thioredoxin-1, administered as a 72-hour infusion every 21 days in patients with advanced cancers refractory to standard therapy.S100-A10, thioredoxin, and S100-A6 as biomarkers of papillary thyroid carcinoma with lymph node metastasis identified by MALDI imaging.Antiproliferative effect of gold(I) compound auranofin through inhibition of STAT3 and telomerase activity in MDA-MB 231 human breast cancer cells.Toxoplasma gondii excretory secretory antigenic proteins of diagnostic potential.Redox control systems in the nucleus: mechanisms and functions.Annatto constituent cis-bixin has selective antimyeloma effects mediated by oxidative stress and associated with inhibition of thioredoxin and thioredoxin reductaseUpdates of reactive oxygen species in melanoma etiology and progression.Thioredoxin-like 2 regulates human cancer cell growth and metastasis via redox homeostasis and NF-κB signalingRNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy.KEAP1-dependent synthetic lethality induced by AKT and TXNRD1 inhibitors in lung cancerAntitumor agent PX-12 inhibits HIF-1α protein levels through an Nrf2/PMF-1-mediated increase in spermidine/spermine acetyl transferase.Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1-JNK1 pathway in HepG2 cellsDermcidin exerts its oncogenic effects in breast cancer via modulation of ERBB signaling.Disorder of G2-M Checkpoint Control in Aniline-Induced Cell Proliferation in Rat Spleen.The relationship of thioredoxin-1 and cisplatin resistance: its impact on ROS and oxidative metabolism in lung cancer cells.CLIC4 is a tumor suppressor for cutaneous squamous cell cancer.Over-expression of Thioredoxin-1 mediates growth, survival, and chemoresistance and is a druggable target in diffuse large B-cell lymphoma.Thioredoxin induces Tregs to generate an immunotolerant tumor microenvironment in metastatic melanoma.The induction of thioredoxin-1 by epinephrine withdraws stress via interaction with β-arrestin-1.Nitrosothiol-Trapping-Based Proteomic Analysis of S-Nitrosylation in Human Lung Carcinoma CellsPhospho-ibuprofen (MDC-917) suppresses breast cancer growth: an effect controlled by the thioredoxin system.Thioredoxin 1 mediates TGF-β-induced epithelial-mesenchymal transition in salivary adenoid cystic carcinomaMaster redox regulator Trx1 upregulates SMYD1 & modulates lysine methylation.The chemopreventive and clinically used agent curcumin sensitizes HPV (-) but not HPV (+) HNSCC to ionizing radiation, in vitro and in a mouse orthotopic model.Thioredoxin and thioredoxin target proteins: from molecular mechanisms to functional significance.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Thioredoxin signaling as a target for cancer therapy.
@en
type
label
Thioredoxin signaling as a target for cancer therapy.
@en
prefLabel
Thioredoxin signaling as a target for cancer therapy.
@en
P1476
Thioredoxin signaling as a target for cancer therapy.
@en
P2093
D Lynn Kirkpatrick
P304
P356
10.1016/J.COPH.2007.04.003
P50
P577
2007-07-03T00:00:00Z