Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomains.
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Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complexADCY5 couples glucose to insulin secretion in human isletsAKAP79, PKC, PKA and PDE4 participate in a Gq-linked muscarinic receptor and adenylate cyclase 2 cAMP signalling complexSelective coupling of type 6 adenylyl cyclase with type 2 IP3 receptors mediates direct sensitization of IP3 receptors by cAMPDependence of multidrug resistance protein-mediated cyclic nucleotide efflux on the background sodium conductanceSignaling Interactions in the Adrenal CortexGenetically-encoded tools for cAMP probing and modulation in living systemsCardiac cAMP: production, hydrolysis, modulation and detectionMolecular mechanism of pancreatic and salivary gland fluid and HCO3 secretionSpatial control of cAMP signalling in health and diseaseCyclic AMP dynamics in the pancreatic β-cellModern concepts concerning the origin of the heartbeat.Regulation of nephron water and electrolyte transport by adenylyl cyclasesCalcium signals driven by single channel noiseNeuronal and glial purinergic receptors functions in neuron development and brain diseaseStructural Basis for Inhibition of Mammalian Adenylyl Cyclase by Calcium †Gα(i/o)-coupled receptor-mediated sensitization of adenylyl cyclase: 40 years laterRegulation of inositol 1,4,5-trisphosphate receptors by cAMP independent of cAMP-dependent protein kinaseType VI adenylyl cyclase regulates neurite extension by binding to Snapin and Snap25Differentially expressed adenylyl cyclase isoforms mediate secretory functions in cholangiocyte subpopulation.Adenylyl cyclase 8 is central to glucagon-like peptide 1 signalling and effects of chronically elevated glucose in rat and human pancreatic beta cellsAKAP79/150 interacts with AC8 and regulates Ca2+-dependent cAMP synthesis in pancreatic and neuronal systemsSmall molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytesPalmitoylation targets AKAP79 protein to lipid rafts and promotes its regulation of calcium-sensitive adenylyl cyclase type 8Differential dopamine receptor subtype regulation of adenylyl cyclases in lipid rafts in human embryonic kidney and renal proximal tubule cellsMechanisms of cyclic AMP compartmentation revealed by computational models.Spatial and temporal second messenger codes for growth cone turningCa²⁺-dependent phosphorylation of Ca²⁺ cycling proteins generates robust rhythmic local Ca²⁺ releases in cardiac pacemaker cells.A plasma membrane microdomain compartmentalizes ephrin-generated cAMP signals to prune developing retinal axon arbors.Neuronal Cell Bodies Remotely Regulate Axonal Growth Response to Localized Netrin-1 Treatment via Second Messenger and DCC DynamicsCyclic AMP accelerates calcium waves in pancreatic acinar cellsDuplexed label-free G protein--coupled receptor assays for high-throughput screening.Imaging cytoplasmic cAMP in mouse brainstem neuronsGlucose-dependent insulinotropic polypeptide signaling in pancreatic β-cells and adipocytesMicrodomain-specific localization of functional ion channels in cardiomyocytes: an emerging concept of local regulation and remodelling.A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker.Extracellular ATP protects pancreatic duct epithelial cells from alcohol-induced damage through P2Y1 receptor-cAMP signal pathway.beta-Adrenergic activation of electrogenic K+ and Cl- secretion in guinea pig distal colonic epithelium proceeds via separate cAMP signaling pathways.Caveolae create local signalling domains through their distinct protein content, lipid profile and morphologyThe calmodulin-stimulated adenylate cyclase ADCY8 sets the sensitivity of zebrafish retinal axons to midline repellents and is required for normal midline crossing.
P2860
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P2860
Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomains.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomains.
@en
type
label
Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomains.
@en
prefLabel
Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomains.
@en
P1476
Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomains.
@en
P2093
Debbie Willoughby
Dermot M F Cooper
P304
P356
10.1152/PHYSREV.00049.2006
P577
2007-07-01T00:00:00Z