Small-molecule pyrimidine inhibitors of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases: development of chemical probe ML315.
about
DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down SyndromeIdentification of a novel function of CX-4945 as a splicing regulatorIdentification of CLK1 Inhibitors by a Fragment-linking Based Virtual Screening.Synthesis and SAR studies of novel 6,7,8-substituted 4-substituted benzyloxyquinolin-2(1H)-one derivatives for anticancer activityThe Tumor Suppressor NKX3.1 Is Targeted for Degradation by DYRK1B KinaseInhibition of DYRK1A Stimulates Human β-Cell ProliferationPharmacology of Modulators of Alternative Splicing.DYRK1A inhibition as potential treatment for Alzheimer's disease.Synthesis of Thiazolo[5,4-f]quinazolin-9(8H)-ones as Multi-Target Directed Ligands of Ser/Thr Kinases.Kororamides, Convolutamines, and Indole Derivatives as Possible Tau and Dual-Specificity Kinase Inhibitors for Alzheimer's Disease: A Computational Study
P2860
Q26745413-9EB3809C-DA7C-4EE0-8C0C-E153932FF467Q28537999-2DAC6548-63A8-4DA5-AF64-02B6C1FC1A1AQ30396689-07606421-EB68-4C10-AA2B-E867506337C2Q35111443-57BEFC4D-884E-474C-A29A-EECBC452CDE8Q35578920-BE59C10C-5BA5-43B4-9667-1D9AB1B9EEDEQ36930761-001F4BDA-4F02-4846-973D-61AB2B8F939EQ38776406-7FAADB6C-2D25-4DFA-9E24-21C8A5566B07Q38807264-AC4E4F9C-DEB9-475F-97C5-745BDCEC33BDQ53377444-0C671C28-D733-410B-B833-5C78B7176178Q58557345-B2B967AD-CACA-4D57-9457-0BB64BF8C559
P2860
Small-molecule pyrimidine inhibitors of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases: development of chemical probe ML315.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Small-molecule pyrimidine inhi ...... pment of chemical probe ML315.
@en
type
label
Small-molecule pyrimidine inhi ...... pment of chemical probe ML315.
@en
prefLabel
Small-molecule pyrimidine inhi ...... pment of chemical probe ML315.
@en
P2093
P2860
P1476
Small-molecule pyrimidine inhi ...... pment of chemical probe ML315.
@en
P2093
Cordelle Tanega
Craig J Thomas
Douglas S Auld
Frank J Schoenen
Jeffrey Aubé
Jenna L Wang
Samuel W Gerritz
Thomas C Coombs
P2860
P304
P356
10.1016/J.BMCL.2013.02.096
P407
P577
2013-03-30T00:00:00Z