Synthesis and evaluation of 3-aryloxymethyl-1,2-dimethylindole-4,7-diones as mechanism-based inhibitors of NAD(P)H:quinone oxidoreductase 1 (NQO1) activity.
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Mechanism-Based Inhibition of Quinone Reductase 2 (NQO2): Selectivity for NQO2 over NQO1 and Structural Basis for Flavoprotein InhibitionAntitumor indolequinones induced apoptosis in human pancreatic cancer cells via inhibition of thioredoxin reductase and activation of redox signaling.Natural and synthetic quinones and their reduction by the quinone reductase enzyme NQO1: from synthetic organic chemistry to compounds with anticancer potential.Potent activity of indolequinones against human pancreatic cancer: identification of thioredoxin reductase as a potential target.Synthesis and Intracellular Redox Cycling of Natural Quinones and Their Analogues and Identification of Indoleamine-2,3-dioxygenase (IDO) as Potential Target for Anticancer Activity.Indolequinone inhibitors of NRH:quinone oxidoreductase 2. Characterization of the mechanism of inhibition in both cell-free and cellular systems.Copper(II)-Mediated Synthesis of Indolequinones from Bromoquinones and Enamines.Effect of β-Eudesmol on NQO1 suppression-enhanced sensitivity of cholangiocarcinoma cells to chemotherapeutic agents.
P2860
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P2860
Synthesis and evaluation of 3-aryloxymethyl-1,2-dimethylindole-4,7-diones as mechanism-based inhibitors of NAD(P)H:quinone oxidoreductase 1 (NQO1) activity.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Synthesis and evaluation of 3- ...... doreductase 1 (NQO1) activity.
@en
type
label
Synthesis and evaluation of 3- ...... doreductase 1 (NQO1) activity.
@en
prefLabel
Synthesis and evaluation of 3- ...... doreductase 1 (NQO1) activity.
@en
P2093
P2860
P356
P1476
Synthesis and evaluation of 3- ...... doreductase 1 (NQO1) activity.
@en
P2093
Aurélie Chilloux
David Ross
David Siegel
Marie A Colucci
Philip Reigan
P2860
P304
P356
10.1021/JM070396Q
P407
P577
2007-10-18T00:00:00Z