Adenosine A2A receptor activation inhibits T helper 1 and T helper 2 cell development and effector function. - Wikidata - wikimedia - TriplyDB

Adenosine A2A receptor activation inhibits T helper 1 and T helper 2 cell development and effector function.

Adenosine A2A receptor activation inhibits T helper 1 and T helper 2 cell development and effector function.

http://www.wikidata.org/entity/Q36879416

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Adenosine receptors: therapeutic aspects for inflammatory and immune diseases.CD73 and CD39 ectonucleotidases in T cell differentiation: Beyond immunosuppression The immunosuppressive role of adenosine A2A receptors in ischemia reperfusion injury and islet transplantation.The A2B adenosine receptor promotes Th17 differentiation via stimulation of dendritic cell IL-6 Immunological alterations mediated by adenosine during host-microbial interactions Search for adenosine A2A spare receptors on peripheral human lymphocytes Adenosine A2A receptor activation protects CD4+ T lymphocytes against activation-induced cell death.Soluble mediators regulating immunity in early life The A2aR adenosine receptor controls cytokine production in iNKT cells Deficits in endogenous adenosine formation by ecto-5'-nucleotidase/CD73 impair neuromuscular transmission and immune competence in experimental autoimmune myasthenia gravis.Selective inhibition of KCa3.1 channels mediates adenosine regulation of the motility of human T cells IRF-5-Mediated Inflammation Limits CD8+ T Cell Expansion by Inducing HIF-1α and Impairing Dendritic Cell Functions during Leishmania Infection Ecto-5'-Nucleotidase (CD73) Deficiency in Mycobacterium tuberculosis-Infected Mice Enhances Neutrophil Recruitment Investigational A₃ adenosine receptor targeting agents.Inhibition of Gαs/cAMP Signaling Decreases TCR-Stimulated IL-2 transcription in CD4(+) T Helper Cells.Role of adenosine A(2B) receptors in inflammation.Adenosine-generating ovarian cancer cells attract myeloid cells which differentiate into adenosine-generating tumor associated macrophages - a self-amplifying, CD39- and CD73-dependent mechanism for tumor immune escape Soluble ecto-5'-nucleotidase (5'-NT), alkaline phosphatase, and adenosine deaminase (ADA1) activities in neonatal blood favor elevated extracellular adenosine.The adenosine A₂A receptor - myocardial protectant and coronary target in endotoxemia.Resetting microbiota by Lactobacillus reuteri inhibits T reg deficiency-induced autoimmunity via adenosine A2A receptors.KLRG1 restricts memory T cell antitumor immunity.Regulation of lymphocyte function by adenosine.Targeting CD73 and downstream adenosine receptor signaling in triple-negative breast cancer.Purinergic signalling and immune cells.Adenosine and adenosine receptors in the pathogenesis and treatment of rheumatic diseases.Targeting adenosine in cancer immunotherapy: a review of recent progress.Purinergic signalling links mechanical breath profile and alveolar mechanics with the pro-inflammatory innate immune response causing ventilation-induced lung injury.Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity.Adenosine produced from adenine nucleotides through an interaction between apoptotic cells and engulfing macrophages contributes to the appearance of transglutaminase 2 in dying thymocytes.CD73-mediated adenosine production promotes stem cell-like properties in mouse Tc17 cells.Mechanisms of allergen-specific immunotherapy and immune tolerance to allergens.Intestinal immunopathology is associated with decreased CD73-generated adenosine during lethal infection.Human follicular lymphoma CD39+-infiltrating T cells contribute to adenosine-mediated T cell hyporesponsiveness.Expression of CD39 by human peripheral blood CD4+ CD25+ T cells denotes a regulatory memory phenotype.Myeloid expression of adenosine A2A receptor suppresses T and NK cell responses in the solid tumor microenvironment.Adenosine deaminase potentiates the generation of effector, memory, and regulatory CD4+ T cells.Adenosine A2A Receptor Deletion Blocks the Beneficial Effects of Lactobacillus reuteri in Regulatory T-Deficient Scurfy Mice.Adenosine receptors differentially regulate type 2 cytokine production by IL-33-activated bone marrow cells, ILC2s, and macrophages.The Hypoxia-Adenosine Link during Intestinal Inflammation.Adenosine metabolism, immunity and joint health.

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Adenosine A2A receptor activation inhibits T helper 1 and T helper 2 cell development and effector function.

http://www.wikidata.org/entity/Q36879416

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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Adenosine A2A receptor activat ...... lopment and effector function.

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Adenosine A2A receptor activat ...... lopment and effector function.

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Adenosine A2A receptor activat ...... elopment and effector function

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Catherine Ledent

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E Sylvester Vizi

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György Haskó

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Leonóra Himer

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Zoltán H Németh

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Zoltán Spolarics

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Zsolt Selmeczy

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P2860

Patterns of A2A extracellular adenosine receptor expression in different functional subsets of human peripheral T cells. Flow cytometry studies with anti-A2A receptor monoclonal antibodies

Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor

Shaping of monocyte and macrophage function by adenosine receptors

Crucial role for ecto-5'-nucleotidase (CD73) in vascular leakage during hypoxia.

International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors

Helper T cell differentiation is controlled by the cell cycle

Receptors for purines and pyrimidines

Gene dose effect reveals no Gs-coupled A2A adenosine receptor reserve in murine T-lymphocytes: studies of cells from A2A-receptor-gene-deficient mice

Neutrophil-epithelial crosstalk at the intestinal lumenal surface mediated by reciprocal secretion of adenosine and IL-6

Role of A2a extracellular adenosine receptor-mediated signaling in adenosine-mediated inhibition of T-cell activation and expansion

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3491-3499

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10.1096/FJ.08-107458

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10

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22

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Edwin A. Deitch

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2008-07-14T00:00:00Z

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5226049

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18625677

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2537430

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