Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation - Wikidata - wikimedia - TriplyDB

Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation

Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation

http://www.wikidata.org/entity/Q36893499

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Disrupted regulatory T cell homeostasis in inflammatory bowel diseases Treg functional stability and its responsiveness to the microenvironment The role of epigenetic mechanisms and processes in autoimmune disorders Different subtypes of GABA-A receptors are expressed in human, mouse and rat T lymphocytes Regulation of DNA replication timing on human chromosome by a cell-type specific DNA binding protein SATB1 Once a Treg, always a Treg?Highlights of the advances in basic immunology in 2011.Genome organizing function of SATB1 in tumor progression.A novel and effective method to generate human porcine-specific regulatory T cells with high expression of IL-10, TGF-β1 and IL-35 Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells Effector bottleneck: microbial reprogramming of parasitized host cell transcription by epigenetic remodeling of chromatin structure.Complex interactions of transcription factors in mediating cytokine biology in T cells.Transcriptional and epigenetic control of T helper cell specification: molecular mechanisms underlying commitment and plasticity.A special population of regulatory T cells potentiates muscle repair.High-resolution transcriptome of human macrophages.Overexpression of miR-21-5p as a predictive marker for complete tumor regression to neoadjuvant chemoradiotherapy in rectal cancer patients miR-182 and miR-10a are key regulators of Treg specialisation and stability during Schistosome and Leishmania-associated inflammation Phosphorylated SATB1 is associated with the progression and prognosis of glioma.Identification of CD34+ and CD34- leukemia-initiating cells in MLL-rearranged human acute lymphoblastic leukemia Gene expression profiles associated with pediatric relapsed AML.An anti-silencer- and SATB1-dependent chromatin hub regulates Rag1 and Rag2 gene expression during thymocyte development Comparative analysis of anti-viral transcriptomics reveals novel effects of influenza immune antagonism Comparative Analysis of Protocols to Induce Human CD4+Foxp3+ Regulatory T Cells by Combinations of IL-2, TGF-beta, Retinoic Acid, Rapamycin and Butyrate Tissue resident regulatory T cells: novel therapeutic targets for human disease.Effect of silencing SATB1 on proliferation, invasion and apoptosis of A549 human lung adenocarcinoma cells MicroRNA-15b/16 Enhances the Induction of Regulatory T Cells by Regulating the Expression of Rictor and mTOR Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment.A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells.Mannose receptor induces T-cell tolerance via inhibition of CD45 and up-regulation of CTLA-4.Combining genetic mapping with genome-wide expression in experimental autoimmune encephalomyelitis highlights a gene network enriched for T cell functions and candidate genes regulating autoimmunity.Special AT-rich DNA-binding protein-1 expression is associated with liver cancer metastasis.Bach2 regulates homeostasis of Foxp3+ regulatory T cells and protects against fatal lung disease in mice.Chromatin Remodeling Protein SMAR1 Is a Critical Regulator of T Helper Cell Differentiation and Inflammatory Diseases.Chromatin organizer SATB1 is an important determinant of T-cell differentiation.One way to pathogenesis, many ways to homeostasis.MicroRNA regulation of T-cell development.Holistic systems biology approaches to molecular mechanisms of human helper T cell differentiation to functionally distinct subsets.Phenotypic alterations, clinical impact and therapeutic potential of regulatory T cells in cancer.Induced regulatory T cells in inhibitory microenvironments created by cancer.Role of tissue-specific AT-rich DNA sequence-binding proteins in lymphocyte differentiation.

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P2860

Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation

http://www.wikidata.org/entity/Q36893499

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2011 nî lūn-bûn

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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Repression of the genome organ ...... on of effector differentiation

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Repression of the genome organ ...... on of effector differentiation

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Repression of the genome organ ...... on of effector differentiation

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Andrea Hofmann

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Andreas Limmer

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Andreas Waha

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Christian T Mayer

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Claudia Wickenhauser

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Daniel Sommer

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Elmar Endl

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Eva A Schönfeld

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Günter Mayer

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Jeffrey A Bluestone

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P2860

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression

A tissue-specific MAR/SAR DNA-binding protein with unusual binding site recognition

Foxp3 occupancy and regulation of key target genes during T-cell stimulation

Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

Control of regulatory T cell development by the transcription factor Foxp3

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Tissue-specific nuclear architecture and gene expression regulated by SATB1

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898-907

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10.1038/NI.2084

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9

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12

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Joachim Schultze

Bernhard Schermer

Percy A. Knolle

Jan P Böttcher

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2011-08-14T00:00:00Z

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51571614

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1002295466

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21841785

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3669688

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