about
FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repressioncIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomasCTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanismsHuman CD8+ T cells do not require the polarization of lipid rafts for activation and proliferationDistinct effects of IL-18 on the engraftment and function of human effector CD8 T cells and regulatory T cellsRetinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cellsCutting Edge: a novel, human-specific interacting protein couples FOXP3 to a chromatin-remodeling complex that contains KAP1/TRIM28Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleasesRegulatory T cells and human myeloid dendritic cells promote tolerance via programmed death ligand-1.Stabilized human TRIM5α protects human T cells from HIV-1 infection.HIV sequence variation associated with env antisense adoptive T-cell therapy in the hNSG mouse modelEngineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases.Clinical grade manufacturing of human alloantigen-reactive regulatory T cells for use in transplantation.Multifactorial T-cell hypofunction that is reversible can limit the efficacy of chimeric antigen receptor-transduced human T cells in solid tumorsSteric shielding of surface epitopes and impaired immune recognition induced by the ebola virus glycoprotein.The battle over mTOR: an emerging theatre in host-pathogen immunityThe CD28 signaling pathway regulates glucose metabolism.The human CD8β M-4 isoform dominant in effector memory T cells has distinct cytoplasmic motifs that confer unique properties.Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells.Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells.The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation.Constitutive cell surface association between CD4 and CCR5.Productive infection of neonatal CD8+ T lymphocytes by HIV-1.Modulation of susceptibility to HIV-1 infection by the cytotoxic T lymphocyte antigen 4 costimulatory molecule.Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiationStrength of PD-1 signaling differentially affects T-cell effector functions.Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains.Adoptive immunotherapy: good habits instilled at youth have long-term benefits.Simultaneous zinc-finger nuclease editing of the HIV coreceptors ccr5 and cxcr4 protects CD4+ T cells from HIV-1 infection.Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules.Expression of a functional CCR2 receptor enhances tumor localization and tumor eradication by retargeted human T cells expressing a mesothelin-specific chimeric antibody receptor.Cutaneous T cell lymphoma expresses immunosuppressive CD80 (B7-1) cell surface protein in a STAT5-dependent manner.Differential regulation of HIV-1 fusion cofactor expression by CD28 costimulation of CD4+ T cells.Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells.Kruppel-like factor 2 modulates CCR5 expression and susceptibility to HIV-1 infection.Suppression of HIV-1 infection in primary CD4 T cells transduced with a self-inactivating lentiviral vector encoding a membrane expressed gp41-derived fusion inhibitor.FOXP3 is a homo-oligomer and a component of a supramolecular regulatory complex disabled in the human XLAAD/IPEX autoimmune disease.Folate receptor alpha and caveolae are not required for Ebola virus glycoprotein-mediated viral infection.DC-SIGN and DC-SIGNR bind ebola glycoproteins and enhance infection of macrophages and endothelial cells.A cell-based artificial antigen-presenting cell coated with anti-CD3 and CD28 antibodies enables rapid expansion and long-term growth of CD4 T lymphocytes.
P50
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P50
description
hulumtues
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researcher
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wetenschapper
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հետազոտող
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name
James L. Riley
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James L. Riley
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James L. Riley
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James L. Riley
@nl
James L. Riley
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type
label
James L. Riley
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James L. Riley
@en
James L. Riley
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James L. Riley
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James L. Riley
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prefLabel
James L. Riley
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James L. Riley
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James L. Riley
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James L. Riley
@nl
James L. Riley
@sl
P106
P1153
7402484456
P21
P31
P496
0000-0002-1057-576X