Role of the ubiquitin ligase E6AP/UBE3A in controlling levels of the synaptic protein Arc
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Ubiquitin-dependent trafficking and turnover of ionotropic glutamate receptorsFrom UBE3A to Angelman syndrome: a substrate perspectiveAngelman Syndrome Protein Ube3a Regulates Synaptic Growth and Endocytosis by Inhibiting BMP Signaling in DrosophilaEpigenetic regulation of UBE3A and roles in human neurodevelopmental disorders.Seizure-like activity in a juvenile Angelman syndrome mouse model is attenuated by reducing Arc expression.Dynamic Arc SUMOylation and Selective Interaction with F-Actin-Binding Protein Drebrin A in LTP Consolidation In Vivo.E3 Ubiquitin Ligases Neurobiological Mechanisms: Development to DegenerationSodium-potassium ATPase emerges as a player in hippocampal phenotypes of Angelman syndrome mice.Intellectual disability and autism spectrum disorders: causal genes and molecular mechanisms.A fine balance: Regulation of hippocampal Arc/Arg3.1 transcription, translation and degradation in a rat model of normal cognitive aging.Triad3A regulates synaptic strength by ubiquitination of Arc.Role of ubiquitin and the HPV E6 oncoprotein in E6AP-mediated ubiquitinationA novel form of synaptic plasticity in field CA3 of hippocampus requires GPER1 activation and BDNF releaseNeurodevelopmental Underpinnings of Angelman Syndrome.Monogenic mouse models of autism spectrum disorders: Common mechanisms and missing links.GABAergic Neuron-Specific Loss of Ube3a Causes Angelman Syndrome-Like EEG Abnormalities and Enhances Seizure Susceptibility.Potential therapeutic approaches for Angelman syndrome.The active form of E6-associated protein (E6AP)/UBE3A ubiquitin ligase is an oligomer.Genomic imprinting in development, growth, behavior and stem cellsAngelman syndrome: review of clinical and molecular aspects.The role of ubiquitin and ubiquitin-like modification systems in papillomavirus biology.HECT-type E3 ubiquitin ligases in nerve cell development and synapse physiology.Perturbed proteostasis in autism spectrum disorders.LDAP: a web server for lncRNA-disease association prediction.Angelman syndrome: Current and emerging therapies in 2016.Ubiquitination and the Regulation of Membrane Proteins.Bimolecular Fluorescence Complementation to Assay the Interactions of Ubiquitylation Enzymes in Living Yeast Cells.Autism gene Ube3a and seizures impair sociability by repressing VTA Cbln1.Activity-Dependent Arc Expression and Homeostatic Synaptic Plasticity Are Altered in Neurons from a Mouse Model of Angelman Syndrome.mTORC1-S6K1 inhibition or mTORC2 activation improves hippocampal synaptic plasticity and learning in Angelman syndrome miceThe autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome.Neuronal overexpression of Ube3a isoform 2 causes behavioral impairments and neuroanatomical pathology relevant to 15q11.2-q13.3 duplication syndrome.Pharmacological therapies for Angelman syndrome.Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10.Roles for Arc in metabotropic glutamate receptor-dependent LTD and synapse elimination: Implications in health and disease.Network analysis of UBE3A/E6AP-associated proteins provides connections to several distinct cellular processes.OTUD7A Regulates Neurodevelopmental Phenotypes in the 15q13.3 Microdeletion Syndrome.Insights into the ubiquitin-proteasome system of human embryonic stem cells.Lovastatin suppresses hyperexcitability and seizure in Angelman syndrome model.Structural dynamics of the E6AP/UBE3A-E6-p53 enzyme-substrate complex
P2860
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P2860
Role of the ubiquitin ligase E6AP/UBE3A in controlling levels of the synaptic protein Arc
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Role of the ubiquitin ligase E6AP/UBE3A in controlling levels of the synaptic protein Arc
@en
type
label
Role of the ubiquitin ligase E6AP/UBE3A in controlling levels of the synaptic protein Arc
@en
prefLabel
Role of the ubiquitin ligase E6AP/UBE3A in controlling levels of the synaptic protein Arc
@en
P2093
P2860
P356
P1476
Role of the ubiquitin ligase E6AP/UBE3A in controlling levels of the synaptic protein Arc
@en
P2093
Benedikt Mothes
Konstantin Matentzoglu
Simone Kühnle
P2860
P304
P356
10.1073/PNAS.1302792110
P407
P577
2013-05-13T00:00:00Z