Aging. Aging-induced type I interferon response at the choroid plexus negatively affects brain function. - Wikidata - wikimedia - TriplyDB

Aging. Aging-induced type I interferon response at the choroid plexus negatively affects brain function.

Aging. Aging-induced type I interferon response at the choroid plexus negatively affects brain function.

http://www.wikidata.org/entity/Q36907335

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Central Nervous System-Peripheral Immune System Dialogue in Neurological Disorders: Possible Application of Neuroimmunology in Urology The choroid plexus-cerebrospinal fluid interface in Alzheimer's disease: more than just a barrier Exosomes as Novel Regulators of Adult Neurogenic Niches Systematic Review of the Neurobiological Relevance of Chemokines to Psychiatric Disorders Blood-Borne Revitalization of the Aged Brain The choroid plexus is modulated by various peripheral stimuli: implications to diseases of the central nervous system Development and functions of the choroid plexus-cerebrospinal fluid system Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug.Emerging Roles for the Immune System in Traumatic Brain Injury Lymphatics in Neurological Disorders: A Neuro-Lympho-Vascular Component of Multiple Sclerosis and Alzheimer's Disease?Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour.Old Maids: Aging and Its Impact on Microglia Function.Hypothalamic stem cells control ageing speed partly through exosomal miRNAs.DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease.Human umbilical cord plasma proteins revitalize hippocampal function in aged mice.Bone marrow-derived macrophages from aged rats are more responsive to inflammatory stimuli.Soluble amyloid triggers a myeloid differentiation factor 88 and interferon regulatory factor 7 dependent neuronal type-1 interferon response in vitro Coronary artery calcifications predict long term cardiovascular events in non diabetic Caucasian hemodialysis patients.Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis.Cerebral nitric oxide represses choroid plexus NFκB-dependent gateway activity for leukocyte trafficking Interdependent and independent roles of type I interferons and IL-6 in innate immune, neuroinflammatory and sickness behaviour responses to systemic poly I:C.Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology Lack of Neuronal IFN-β-IFNAR Causes Lewy Body- and Parkinson's Disease-like Dementia Splenocytes derived from young WT mice prevent AD progression in APPswe/PSENldE9 transgenic mice Ablation of Type-1 IFN Signaling in Hematopoietic Cells Confers Protection Following Traumatic Brain Injury The adaptive immune system restrains Alzheimer's disease pathogenesis by modulating microglial function.Induction of the type I interferon response in neurological forms of Gaucher disease The retinal pigment epithelium as a gateway for monocyte trafficking into the eye.Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor.Deletion of the type-1 interferon receptor in APPSWE/PS1ΔE9 mice preserves cognitive function and alters glial phenotype MCP-1 and eotaxin-1 selectively and negatively associate with memory in MCI and Alzheimer's disease dementia phenotypes.Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer's disease.Comment on "Multiple repressive mechanisms in the hippocampus during memory formation".T Lymphocytes and Inflammatory Mediators in the Interplay between Brain and Blood in Alzheimer's Disease: Potential Pools of New Biomarkers.The choroid plexuses and their impact on developmental neurogenesis.It takes a village: constructing the neurogenic niche.Bone, brain & beyond.Type-I interferon pathway in neuroinflammation and neurodegeneration: focus on Alzheimer's disease.Microglia-dependent synapse loss in type I interferon-mediated lupus.

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Aging. Aging-induced type I interferon response at the choroid plexus negatively affects brain function.

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Dana Bezalel

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Ido Amit

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Differential expression analysis for sequence count data

Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance

T cell deficiency leads to cognitive dysfunction: implications for therapeutic vaccination for schizophrenia and other psychiatric conditions.

The ageing systemic milieu negatively regulates neurogenesis and cognitive function.

TopHat: discovering splice junctions with RNA-Seq

Immunomodulatory functions of type I interferons

Vascular and neurogenic rejuvenation of the aging mouse brain by young systemic factors

Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood

Ab initio reconstruction of cell type-specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs

Rejuvenation of aged progenitor cells by exposure to a young systemic environment

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