Blockade of glucagon signaling prevents or reverses diabetes onset only if residual β-cells persist. - Wikidata - wikimedia - TriplyDB

Blockade of glucagon signaling prevents or reverses diabetes onset only if residual β-cells persist.

Blockade of glucagon signaling prevents or reverses diabetes onset only if residual β-cells persist.

http://www.wikidata.org/entity/Q36913461

about

Glucagon receptor gene deletion in insulin knockout mice modestly reduces blood glucose and ketones but does not promote survival Modeling Pancreatic Endocrine Cell Adaptation and Diabetes in the Zebrafish.Hypoglycemic Effect of Combined Ghrelin and Glucagon Receptor Blockade.The New Biology and Pharmacology of Glucagon.Angptl4 does not control hyperglucagonemia or α-cell hyperplasia following glucagon receptor inhibition.Glucagon receptor inhibition normalizes blood glucose in severe insulin-resistant mice.The glucoregulatory actions of leptin.Glucagon antagonism in islet cell proliferation.Kinetics of functional beta cell mass decay in a diphtheria toxin receptor mouse model of diabetes.Partners for life.Lipid nanoparticle delivery of glucagon receptor siRNA improves glucose homeostasis in mouse models of diabetes Regulation of amino acid metabolism and alpha cell proliferation by glucagon.Investigational glucagon receptor antagonists in Phase I and II clinical trials for diabetes.Current Therapies That Modify Glucagon Secretion: What Is the Therapeutic Effect of Such Modifications?A first-in-human pharmacodynamic and pharmacokinetic study of a fully human anti-glucagon receptor monoclonal antibody in normal healthy volunteers.Problem or solution: The strange story of glucagon.Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon α-cells SIRT1 activation attenuates α cell hyperplasia, hyperglucagonaemia and hyperglycaemia in STZ-diabetic mice Deletion of the glucagon receptor gene before and after experimental diabetes reveals differential protection from hyperglycemia

P2860

Q28830385-688DCC2F-F7FA-4007-A3EB-47AB6A4CA7A8 Q37607133-AE9AEAAC-2E25-4697-AD29-D1B9D0F30032 Q38795246-64785095-8BFC-4465-AE6F-866D19F7F89A Q38919742-316504CB-BB8B-4E70-9F15-342758367DFB Q38988157-EEE2AE39-F68C-4367-B0E9-2504321E5005 Q39003343-86395BB3-015F-4A7A-97AB-99EFAC693DD3 Q41689705-931A742E-6008-461B-A97F-ABE20860E71B Q41709975-361A0588-5DFD-4129-AEDE-44C1DAB05AF7 Q42172185-FE4CEB67-2B79-4FC3-83E9-AB3750DACF08 Q42214143-8E2796B4-E7AB-42D6-B77E-D5C6EAFD5DC6 Q42377847-59F4C30A-1F40-4752-9135-78F87E5819AE Q47190965-C2DA3E8A-20AB-4BFD-9DB1-BED213EF269A Q47625288-F592164F-8855-48A4-AB43-B119AC8B48CE Q47871565-86230F74-8560-4CD4-BEED-A0F6CB88F7F5 Q48326278-269D80F8-A2DB-441E-9720-DA3B64922AC1 Q50140641-899500E6-95C9-463E-8F1B-A75245A8A601 Q58569394-49C20D8E-4493-421F-B625-EB06222A538E Q58726506-6E1F6B5E-F38E-45FE-AC8D-95668ACAB1EB Q58732217-D73A5938-22FE-40C7-90D8-71FA5837C5C2

P2860

Blockade of glucagon signaling prevents or reverses diabetes onset only if residual β-cells persist.

http://www.wikidata.org/entity/Q36913461

description

2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

Blockade of glucagon signaling ...... y if residual β-cells persist.

@en

type

label

Blockade of glucagon signaling ...... y if residual β-cells persist.

@en

prefLabel

Blockade of glucagon signaling ...... y if residual β-cells persist.

@en

P1433

Q36913461-4838E74C-18AE-4495-82E7-52164211DDFA

P1476

Q36913461-1D047B8C-B2F1-4802-8757-8D760645A176

P2093

Q36913461-33DD85C0-8588-4EFC-A3F2-50553AEBA9CD

Q36913461-7EF3A5F3-C738-41C1-9EF1-0761704FE443

Q36913461-9DB77786-C521-46F6-B1C5-3E0B1DCEC645

Q36913461-C2433250-454C-47AE-AA55-FE91C007404E

Q36913461-F6F98475-551A-4236-9BC1-2F2B7DECAFAF

P2860

Q36913461-160A728A-9F54-4174-88E4-5B3DF0CDD523

Q36913461-161B2257-8A91-4600-9570-6AB6D65C0AA1

Q36913461-173EC18F-7CA6-4E9D-8756-F823202AA9C4

Q36913461-18174105-C5AA-4325-9671-4E5E011FB92A

Q36913461-262CBA78-80F0-490F-8C79-4B4B6919BCE0

Q36913461-2C7CFDD0-30D2-4F60-B186-9C2F4F725BB9

Q36913461-46DE9D7D-4ADE-4B93-9ECE-E99C3FDA0229

Q36913461-47CEED92-FCCB-4386-A57E-E7E6B5AF7555

Q36913461-4ED740DD-4A8B-4CE2-8201-E4DB64B42CD7

Q36913461-5168EF4E-413C-4DD4-9518-C29524FB199D

P31

Q36913461-D09F8AB4-AEC4-4CE6-A810-326C9F71447D

P356

Q36913461-2F96CF0F-72B4-4DC2-A49E-FFD440E8DEBE

P407

Q36913461-6C365C13-117B-4867-9438-FE769AAB4491

P478

Q36913461-509022E4-B705-4716-B27D-CAB3035FE387

P50

Q36913461-716EC978-D36E-438E-A840-CD72E1A7512C

Q36913461-B4528579-B627-4E70-9142-512B303CA67D

P577

Q36913461-83E987CC-2F12-4274-9586-83588AE4CB2A

P698

Q36913461-AC4ECD9A-8381-44FC-B382-FBB206163B33

P932

Q36913461-C18A76A1-5139-472A-B820-617C82A10425

P356

P1433

P1476

Blockade of glucagon signaling ...... ly if residual β-cells persist

@en

P2093

Alvin C Powers

http://www.w3.org/2001/XMLSchema#string

Fabrizio Thorel

http://www.w3.org/2001/XMLSchema#string

Julie S Moyers

http://www.w3.org/2001/XMLSchema#string

Maureen J Charron

http://www.w3.org/2001/XMLSchema#string

Patricia M Vuguin

http://www.w3.org/2001/XMLSchema#string

P2860

RETRACTED: Betatrophin: a hormone that controls pancreatic β cell proliferation

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Persistence of prolonged C-peptide production in type 1 diabetes as measured with an ultrasensitive C-peptide assay

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

Factors that control the tissue-specific transcription of the gene for phosphoenolpyruvate carboxykinase-C

Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas

Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice

Polyomic profiling reveals significant hepatic metabolic alterations in glucagon-receptor (GCGR) knockout mice: implications on anti-glucagon therapies for diabetes.

Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss

Early restriction of peripheral and proximal cell lineages during formation of the lung.

P31

scholarly article

P356

10.7554/ELIFE.13828

http://www.w3.org/2001/XMLSchema#string

P407

P478

5

http://www.w3.org/2001/XMLSchema#string

P50

Pedro Luis Herrera

P577

2016-04-19T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

27092792

http://www.w3.org/2001/XMLSchema#string

P932

4871705

http://www.w3.org/2001/XMLSchema#string