Translational control by influenza virus: suppression of the kinase that phosphorylates the alpha subunit of initiation factor eIF-2 and selective translation of influenza viral mRNAs
about
The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteinsMolecular cloning of a new interferon-induced factor that represses human immunodeficiency virus type 1 long terminal repeat expressionInhibition of translation in cells infected with a poliovirus 2Apro mutant correlates with phosphorylation of the alpha subunit of eucaryotic initiation factor 2Twenty amino acids at the C-terminus of PA-X are associated with increased influenza A virus replication and pathogenicity.Infection of HLA-DR1 transgenic mice with a human isolate of influenza a virus (H1N1) primes a diverse CD4 T-cell repertoire that includes CD4 T cells with heterosubtypic cross-reactivity to avian (H5N1) influenza virus.Detection of activated double-stranded RNA-dependent protein kinase in 3T3-F442A cells.Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells.Adenovirus inhibition of cellular protein synthesis is prevented by the drug 2-aminopurine.Adenovirus VAI RNA complexes with the 68 000 Mr protein kinase to regulate its autophosphorylation and activityTranslational control of viral gene expression in eukaryotesCyclophilin A restricts influenza A virus replication through degradation of the M1 protein.A comprehensive map of the influenza A virus replication cycleeIF2alpha kinases GCN2 and PERK modulate transcription and translation of distinct sets of mRNAs in mouse liver.The cellular protein P58IPK regulates influenza virus mRNA translation and replication through a PKR-mediated mechanismInfluenza virus NS1 protein enhances the rate of translation initiation of viral mRNAs.PKR Transduces MDA5-Dependent Signals for Type I IFN Induction.The NS1 protein of influenza A virus suppresses interferon-regulated activation of antigen-presentation and immune-proteasome pathways.Interferon alpha (IFN)-macrophage interactions in human immunodeficiency virus (HIV) infection: role of IFN in the tempo and progression of HIV disease.Degradation of the interferon-induced 68,000-M(r) protein kinase by poliovirus requires RNAModification of eukaryotic initiation factor 4F during infection by influenza virus.Identification of the N-terminal domain of the influenza virus PA responsible for the suppression of host protein synthesis.Purification and activation of the double-stranded RNA-dependent eIF-2 kinase DAIEffect of mutations and deletions in a bicistronic mRNA on the synthesis of influenza B virus NB and NA glycoproteins.The cellular 68,000-Mr protein kinase is highly autophosphorylated and activated yet significantly degraded during poliovirus infection: implications for translational regulation.Characterization of the translational defect to fiber synthesis in monkey cells abortively infected with human adenovirus: role of ancillary leaders.Efficient transcription, not translation, is dependent on adenovirus tripartite leader sequences at late times of infection.Cellular mRNA translation is blocked at both initiation and elongation after infection by influenza virus or adenovirusA heat-sensitive inhibitor in poliovirus-infected cells which selectively blocks phosphorylation of the alpha subunit of eucaryotic initiation factor 2 by the double-stranded RNA-activated protein kinaseInfluenza virus regulates protein synthesis during infection by repressing autophosphorylation and activity of the cellular 68,000-Mr protein kinase.Activation of double-stranded RNA-activated protein kinase in HeLa cells after poliovirus infection does not result in increased phosphorylation of eucaryotic initiation factor-2The avian influenza virus nucleoprotein gene and a specific constellation of avian and human virus polymerase genes each specify attenuation of avian-human influenza A/Pintail/79 reassortant viruses for monkeysCrucial role of PA in virus life cycle and host adaptation of influenza A virus.Quantitative analysis of cellular proteome alterations in human influenza A virus-infected mammalian cell lines.Large-population passages of vesicular stomatitis virus in interferon-treated cells select variants of only limited resistance.Interactions between double-stranded RNA regulators and the protein kinase DAI.NF90 is a novel influenza A virus NS1-interacting protein that antagonizes the inhibitory role of NS1 on PKR phosphorylation.Protein synthesis in Drosophila melanogaster embryos. Purification and characterization of polypeptide chain-initiation factor 2.Protein synthesis in Drosophila melanogaster embryos. Two mechanisms for guanine nucleotide exchange on eukaryotic initiation factor 2.
P2860
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P2860
Translational control by influenza virus: suppression of the kinase that phosphorylates the alpha subunit of initiation factor eIF-2 and selective translation of influenza viral mRNAs
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Translational control by influ ...... ation of influenza viral mRNAs
@en
type
label
Translational control by influ ...... ation of influenza viral mRNAs
@en
prefLabel
Translational control by influ ...... ation of influenza viral mRNAs
@en
P2093
P2860
P356
P1476
Translational control by influ ...... ation of influenza viral mRNAs
@en
P2093
P2860
P304
P356
10.1128/MCB.6.5.1741
P407
P577
1986-05-01T00:00:00Z