Segregation and rearrangement of coamplified genes in different lineages of mutant cells that overproduce adenylate deaminase
about
The dihydrofolate reductase amplicons in different methotrexate-resistant Chinese hamster cell lines share at least a 273-kilobase core sequence, but the amplicons in some cell lines are much larger and are remarkably uniform in structure.Organization and genesis of dihydrofolate reductase amplicons in the genome of a methotrexate-resistant Chinese hamster ovary cell line.Transcripts from amplified sequences of an inherited homogeneously staining region in chromosome 1 of the house mouse (Mus musculus)A seryl-tRNA synthetase gene is coamplified with the adenylate deaminase 2 gene in coformycin resistant Chinese hamster fibroblastsUnstable and stable CAD gene amplification: importance of flanking sequences and nuclear environment in gene amplification.Matrix attachment regions and transcription units in a polygenic mammalian locus overlapping two isochores.Enhanced flexibility and aphidicolin-induced DNA breaks near mammalian replication origins: implications for replicon mapping and chromosome fragility.oriGNAI3: a narrow zone of preferential replication initiation in mammalian cells identified by 2D gel and competitive PCR replicon mapping techniques.Preferential amplification of rearranged sequences near amplified adenylate deaminase genes.The multicopy appearance of a large inverted duplication and the sequence at the inversion joint suggest a new model for gene amplification.GNAI3, GNAT2, AMPD2, GSTM are clustered in 120 kb of Chinese hamster chromosome 1q.A hotspot for novel amplification joints in a mosaic of Alu-like repeats and palindromic A + T-rich DNA.Coamplification of mu class glutathione S-transferase genes and an adenylate deaminase gene in coformycin-resistant Chinese hamster fibroblasts.
P2860
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P2860
Segregation and rearrangement of coamplified genes in different lineages of mutant cells that overproduce adenylate deaminase
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Segregation and rearrangement ...... verproduce adenylate deaminase
@en
type
label
Segregation and rearrangement ...... verproduce adenylate deaminase
@en
prefLabel
Segregation and rearrangement ...... verproduce adenylate deaminase
@en
P2093
P2860
P356
P1476
Segregation and rearrangement ...... verproduce adenylate deaminase
@en
P2093
Debatisse M
Petit-Koskas E
de Saint-Vincent BR
P2860
P304
P356
10.1128/MCB.6.5.1776
P407
P577
1986-05-01T00:00:00Z