Phosphatase PTP4A3 Promotes Triple-Negative Breast Cancer Growth and Predicts Poor Patient Survival.
about
Regulatory mechanisms of phosphatase of regenerating liver (PRL)-3PRL-3 engages the focal adhesion pathway in triple-negative breast cancer cells to alter actin structure and substrate adhesion properties critical for cell migration and invasionLoss of the oncogenic phosphatase PRL-3 promotes a TNF-R1 feedback loop that mediates triple-negative breast cancer growth.Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents.Molecular Pathways: Targeting Protein Tyrosine Phosphatases in Cancer.Cell matrix adhesions in cancer: The proteins that form the glue.Gene expression information improves reliability of receptor status in breast cancer patients.PRL‑3 increases the aggressive phenotype of prostate cancer cells in vitro and its expression correlates with high-grade prostate tumors in patients.Expression of phosphatase of regenerating liver (PRL)-3, is independently associated with biochemical failure, clinical failure and death in prostate cancer.Increased expression of GATA zinc finger domain containing 1 through gene amplification promotes liver cancer by directly inducing phosphatase of regenerating liver 3.Therapeutic Targeting of Oncogenic Tyrosine Phosphatases.PRL-3 is a potential glioblastoma prognostic marker and promotes glioblastoma progression by enhancing MMP7 through the ERK and JNK pathways.A loss-of-function genetic screening reveals synergistic targeting of AKT/mTOR and WTN/β-catenin pathways for treatment of AML with high PRL-3 phosphatase.Targeting ovarian cancer and endothelium with an allosteric PTP4A3 phosphatase inhibitor.NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest.A chemical genetics approach identifies PTP4A3 as a regulator of colon cancer cell adhesion
P2860
Q28066318-764C4E59-315F-473A-9F65-8A03ADF6AC87Q33872677-FEF2CAC5-C804-4598-9C41-A0F4105CFEA0Q37224273-CFABCE16-5D6E-4C6E-A83F-11CF351BD383Q37745870-81CAA29A-C4A8-4A74-9229-ABDDD8772951Q39088131-31886837-AC85-48FD-A506-5328E152C351Q39286100-F3D8DA2D-C51F-4771-914B-4A989E5664FBQ43654815-8182209C-3045-4A0B-87D2-4B352FAF91F9Q47104255-2EEC2A5E-5036-4C5D-A3F4-BC581D070524Q47123783-4AC4BBA2-26AA-4CA8-ABF8-2D4F95978008Q47266195-C4E32F8C-3E69-438F-A267-82360FE06D9EQ47881716-54B2EFC8-BFF5-44EB-ADE9-97F9CDE5AC1CQ52647666-515564ED-B809-4163-A139-80C36E089B6EQ52668830-C0397F93-52BD-4D2D-A0E5-6701E0F5BA0BQ52688988-B9278538-B346-4E15-9447-1F129931A164Q54978331-3FE85900-2621-420D-84E6-3425F0088CEDQ56375935-355062EE-8C3F-4E85-9819-7D4E63A4D070
P2860
Phosphatase PTP4A3 Promotes Triple-Negative Breast Cancer Growth and Predicts Poor Patient Survival.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Phosphatase PTP4A3 Promotes Tr ...... redicts Poor Patient Survival.
@en
type
label
Phosphatase PTP4A3 Promotes Tr ...... redicts Poor Patient Survival.
@en
prefLabel
Phosphatase PTP4A3 Promotes Tr ...... redicts Poor Patient Survival.
@en
P2093
P2860
P1433
P1476
Phosphatase PTP4A3 Promotes Tr ...... redicts Poor Patient Survival.
@en
P2093
Abhijit Mazumdar
C Kent Osborne
Gordon B Mills
Jamal Hill
Jenny C Chang
Jonathan Shepherd
Kathryn Rawls
Petra den Hollander
Powel H Brown
Susan G Hilsenbeck
P2860
P304
P356
10.1158/0008-5472.CAN-14-0673
P407
P577
2016-02-26T00:00:00Z