A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb
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MED12 mutations link intellectual disability syndromes with dysregulated GLI3-dependent Sonic Hedgehog signalingEstablishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: the role of negative feedbackHedgehog Signaling in the Maintenance of Cancer Stem CellsBeyond the ENCODE project: using genomics and epigenomics strategies to study enhancer evolutionContext-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapyA dynamic Shh expression pattern, regulated by SHH and BMP signaling, coordinates fusion of primordia in the amniote faceComparative analysis of 3D expression patterns of transcription factor genes and digit fate maps in the developing chick wingChromatin signaling in muscle stem cells: interpreting the regenerative microenvironmentCyclopamine tartrate, an inhibitor of Hedgehog signaling, strongly interferes with mitochondrial function and suppresses aerobic respiration in lung cancer cellsDistinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud developmentA self-organized model for cell-differentiation based on variations of molecular decay ratesHepatic Hedgehog signaling contributes to the regulation of IGF1 and IGFBP1 serum levelsA mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signalingGATA6 is a crucial regulator of Shh in the limb budFoxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septationCilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conservedLimb anterior-posterior polarity integrates activator and repressor functions of GLI2 as well as GLI3Gli1 protein participates in Hedgehog-mediated specification of osteoblast lineage during endochondral ossificationFunctional analysis of limb transcriptional enhancers in the mouseRegeneration in the era of functional genomics and gene network analysis.GLI3 repressor controls functional development of the mouse ureterMouse strain specific gene expression differences for illumina microarray expression profiling in embryos.Combining Hi-C data with phylogenetic correlation to predict the target genes of distal regulatory elements in human genome.Urogenital development in Pallister-Hall syndrome is disrupted in a cell-lineage-specific manner by constitutive expression of GLI3 repressor.Prdm1 (Blimp-1) and the expression of fast and slow myosin heavy chain isoforms during avian myogenesis in vitro.Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb developmentAnalysis of transcription factors expressed at the anterior mouse limb bud.Integrative analysis of genomic, functional and protein interaction data predicts long-range enhancer-target gene interactionsShh pathway activation is present and required within the vertebrate limb bud apical ectodermal ridge for normal autopod patterningEvolution of vertebrate appendicular structures: Insight from genetic and palaeontological data.Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube.Mechanism and evolution of cytosolic Hedgehog signal transductionDifferential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development.JAMIE: joint analysis of multiple ChIP-chip experimentsHedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis.AMD, an automated motif discovery tool using stepwise refinement of gapped consensuses.Sonic hedgehog signaling in the postnatal brain.Yeast-based assay identifies novel Shh/Gli target genes in vertebrate developmentGli3 repressor controls cell fates and cell adhesion for proper establishment of neurogenic niche.Transcriptional enhancers in animal development and evolution
P2860
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P2860
A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A genome-scale analysis of the ...... tterning of the mammalian limb
@en
type
label
A genome-scale analysis of the ...... tterning of the mammalian limb
@en
prefLabel
A genome-scale analysis of the ...... tterning of the mammalian limb
@en
P2093
P2860
P356
P1433
P1476
A genome-scale analysis of the ...... tterning of the mammalian limb
@en
P2093
Andrew P McMahon
Hongkai Ji
Wing H Wong
P2860
P304
P356
10.1101/GAD.1693008
P577
2008-10-01T00:00:00Z