Transient receptor potential vanilloid 4-mediated disruption of the alveolar septal barrier: a novel mechanism of acute lung injury.
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International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel familyStudies on the cell biology of interendothelial cell gapsIn the absence of effector proteins, the Pseudomonas aeruginosa type three secretion system needle tip complex contributes to lung injury and systemic inflammatory responsesPharmacological inhibitors of TRPV4 channels reduce cytokine production, restore endothelial function and increase survival in septic miceThe TRPV4 channel contributes to intercellular junction formation in keratinocytesFocal adhesion kinase and endothelial cell apoptosis.Prevention of ventilator-induced lung edema by inhalation of nanoparticles releasing ruthenium red.Arterial response to shear stress critically depends on endothelial TRPV4 expression.Transient receptor potential (TRP) channels in the airway: role in airway disease.Optimization of a Novel Series of TRPV4 Antagonists with In Vivo Activity in a Model of Pulmonary EdemaTRPing on the lung endothelium: calcium channels that regulate barrier function.A unique pulmonary microvascular endothelial cell niche revealed by Weibel-Palade bodies and Griffonia simplicifoliaTransient receptor potential channels and regulation of lung endothelial permeability.Sensing hot and cold with TRP channels.Perivascular fluid cuffs decrease lung compliance by increasing tissue resistance.Actin cytoskeleton regulates stretch-activated Ca2+ influx in human pulmonary microvascular endothelial cells.TRPV4 channels augment macrophage activation and ventilator-induced lung injury.Role of MMP2 and MMP9 in TRPV4-induced lung injury.Quantitative GPCR and ion channel transcriptomics in primary alveolar macrophages and macrophage surrogatesChondroprotective role of the osmotically sensitive ion channel transient receptor potential vanilloid 4: age- and sex-dependent progression of osteoarthritis in Trpv4-deficient mice.Caspase-1 Activation Protects Lung Endothelial Barrier Function during Infection-Induced Stress.TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor.Role of TRP channels in the cardiovascular system.Adenosine monophosphate-activated kinase alpha1 promotes endothelial barrier repair.Mechanotransduction via TRPV4 regulates inflammation and differentiation in fetal mouse distal lung epithelial cells.Functional coupling of TRPV4, IK, and SK channels contributes to Ca(2+)-dependent endothelial injury in rodent lungUpregulation of osmo-mechanosensitive TRPV4 channel facilitates chronic hypoxia-induced myogenic tone and pulmonary hypertensionTransient receptor potential genes, smoking, occupational exposures and cough in adults.Regulation and function of the two-pore-domain (K2P) potassium channel Trek-1 in alveolar epithelial cells.Transient receptor potential channels in the vasculature.Genetic deficit of KCa 3.1 channels protects against pulmonary circulatory collapse induced by TRPV4 channel activation.Update on vascular endothelial Ca(2+) signalling: A tale of ion channels, pumps and transportersHydrogen peroxide-induced calcium influx in lung microvascular endothelial cells involves TRPV4.TRPV4 Mechanosensitive Ion Channel Regulates Lipopolysaccharide-Stimulated Macrophage Phagocytosis.Endothelium-Derived Hyperpolarization and Coronary Vasodilation: Diverse and Integrated Roles of Epoxyeicosatrienoic Acids, Hydrogen Peroxide, and Gap Junctions.Shear stress regulates aquaporin-5 and airway epithelial barrier functionHigh vascular pressure-induced lung injury requires P450 epoxygenase-dependent activation of TRPV4Transient receptor potential (TRP) channels as a therapeutic target for intervention of respiratory effects and lethality from phosgene.TRPV4 and the regulation of vascular toneActivation of TRPV1-dependent calcium oscillation exacerbates seawater inhalation-induced acute lung injury.
P2860
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P2860
Transient receptor potential vanilloid 4-mediated disruption of the alveolar septal barrier: a novel mechanism of acute lung injury.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Transient receptor potential v ...... echanism of acute lung injury.
@en
type
label
Transient receptor potential v ...... echanism of acute lung injury.
@en
prefLabel
Transient receptor potential v ...... echanism of acute lung injury.
@en
P2093
P2860
P1433
P1476
Transient receptor potential v ...... mechanism of acute lung injury
@en
P2093
David Weber
Emile Addison
Judy A King
Mary I Townsley
Wolfgang Liedtke
P2860
P304
P356
10.1161/01.RES.0000247065.11756.19
P577
2006-09-28T00:00:00Z