Metformin overdose causes platelet mitochondrial dysfunction in humans. - Wikidata - wikimedia - TriplyDB

Metformin overdose causes platelet mitochondrial dysfunction in humans.

Metformin overdose causes platelet mitochondrial dysfunction in humans.

http://www.wikidata.org/entity/Q36928172

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Year in review 2012: Critical Care--Cardiology Mitochondrial changes in platelets are not related to those in skeletal muscle during human septic shock.Platelets and cancer: a casual or causal relationship: revisited.Metformin-induced lactic acidosis with emphasis on the anion gap.Platelet mitochondrial dysfunction in critically ill patients: comparison between sepsis and cardiogenic shock.Therapeutic Concentrations of Metformin: A Systematic Review.Effects of glycemic control on glucose utilization and mitochondrial respiration during resuscitated murine septic shock.Lactic acidosis and severe septic shock in metformin users: a cohort study Metformin overdose: time to move on Acid-base and electrolyte disorders associated with the use of antidiabetic drugs.Metformin-related lactic acidosis: is it a myth or an underestimated reality?The Role of Sodium Bicarbonate in the Management of Some Toxic Ingestions One other explanation for hypoglycemia during metformin overdose.Hypoglycemia and severe lactic acidosis in a dog following metformin exposure.Association Between Stroke Risk and Metformin Use in Hemodialysis Patients With Diabetes Mellitus: A Nested Case-Control Study.Does metformin exposure before ICU stay have any impact on patients' outcome? A retrospective cohort study of diabetic patients.Chronic metformin treatment is associated with reduced myocardial infarct size in diabetic patients with ST-segment elevation myocardial infarction.Metformin induces lactate production in peripheral blood mononuclear cells and platelets through specific mitochondrial complex I inhibition.Impaired aspirin-mediated platelet function inhibition in resuscitated patients with acute myocardial infarction treated with therapeutic hypothermia: a prospective, observational, non-randomized single-centre study.Succinate and the shortcut to the cure of metformin-induced lactic acidosis

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P2860

Metformin overdose causes platelet mitochondrial dysfunction in humans.

http://www.wikidata.org/entity/Q36928172

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Metformin overdose causes platelet mitochondrial dysfunction in humans.

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Metformin overdose causes platelet mitochondrial dysfunction in humans.

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Metformin overdose causes platelet mitochondrial dysfunction in humans.

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Metformin overdose causes platelet mitochondrial dysfunction in humans

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Anna Lecchi

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Barbara Lanticina

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Francesco Fortunato

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Gigliola Fagiolari

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Loredana Faraldi

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Maurizio Moggio

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Noemi Greppi

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Sarah Vecchio

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P2860

Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

Oxygen consumption is depressed in patients with lactic acidosis due to biguanide intoxication.

Lactic acidosis in metformin therapy: searching for a link with metformin in reports of 'metformin-associated lactic acidosis'.

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

Medical management of hyperglycaemia in type 2 diabetes mellitus: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes

Metformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy status

Metformin-induced lactic acidosis: no one left behind

Metformin-associated lactic acidosis in an intensive care unit.

Can acute overdose of metformin lead to lactic acidosis?

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5

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Giovanni Mistraletti

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2012-10-03T00:00:00Z

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