β-arrestin-selective G protein-coupled receptor agonists engender unique biological efficacy in vivo
about
Cell-surface receptors transactivation mediated by g protein-coupled receptorsSystems-Level G Protein-Coupled Receptor Therapy Across a Neurodegenerative Continuum by the GLP-1 Receptor SystemAmitriptyline improves motor function via enhanced neurotrophin signaling and mitochondrial functions in the murine N171-82Q Huntington disease model.Plurigon: three dimensional visualization and classification of high-dimensionality data.Textrous!: extracting semantic textual meaning from gene sets.Delineation of a conserved arrestin-biased signaling repertoire in vivo.Receptor, Ligand and Transducer Contributions to Dopamine D2 Receptor Functional Selectivity.Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.Informatic deconvolution of biased GPCR signaling mechanisms from in vivo pharmacological experimentation.Exploring G protein-coupled receptor signaling networks using SILAC-based phosphoproteomicsGIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging.Minireview: More than just a hammer: ligand "bias" and pharmaceutical discovery.Functional selectivity of GPCR signaling in animals.Diversity and Bias through Receptor-Receptor Interactions in GPCR Heteroreceptor Complexes. Focus on Examples from Dopamine D2 Receptor Heteromerization.Neuropeptides: metabolism to bioactive fragments and the pharmacology of their receptors.Investigational parathyroid hormone receptor analogs for the treatment of osteoporosis.Selectivity of pharmacological tools: implications for use in cell physiology. A review in the theme: Cell signaling: proteins, pathways and mechanisms.The Multiple Waves of Cannabinoid 1 Receptor Signaling.Functional selectivity at G-protein coupled receptors: Advancing cannabinoid receptors as drug targets.G Protein-Coupled Receptor Signaling Through β-Arrestin-Dependent Mechanisms.Translating in vitro ligand bias into in vivo efficacy.The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling.Angiotensin II receptors and peritoneal dialysis-induced peritoneal fibrosis.Structure-inspired design of β-arrestin-biased ligands for aminergic GPCRs.G Protein-Coupled Receptor Endocytosis Confers Uniformity in Responses to Chemically Distinct Ligands.
P2860
Q26827583-AB331703-141E-4837-BBB3-B0861364A2DDQ26999386-5B39DDD4-7F9E-4AAE-96F1-C465B0201E68Q27314860-19B80FF9-43AD-4650-874C-E7DD30461A91Q30657229-161D7F3F-23CD-4492-9BEE-7FA06C2E97C5Q34706809-8F53FD97-AFD7-40A0-B772-594E4F418026Q35198039-244E7BF6-14AF-4F7F-8D8A-0E6ABF269AA9Q35827028-CCB9DD38-451E-4727-97CD-E1D8A1CF3DC1Q35999789-DEE5EEB3-DDC2-4608-9247-A74C092ECE1CQ36284673-8EEB233A-3FB1-4389-A4CC-5FF15DA8F1F3Q36418560-F2AA7A79-38CA-4494-A7D1-49CFBFFC30E3Q36471894-832DFF41-C3DF-4920-B1DC-B7E0589D9C41Q37610141-6679E04A-957D-4171-84DC-9C8E4E9D89E2Q38200337-DC6BE844-2858-4D98-B511-940F85BB07BDQ38214620-68475C77-BE04-4FFD-B43C-1941B8917255Q38217456-A57A253D-AC11-4B2E-90A0-88FBE34A98E1Q38260285-07931B26-0826-47B5-AE7D-9167D779B716Q38336214-0D5FB490-AFEF-475F-87D9-8347A33311B7Q38874828-B3DA61AE-148F-42DE-B1C7-7862A41B6075Q39021630-333D2080-13E5-4395-A7F3-B95EC1EB7BE6Q39193257-5CBCAB77-F925-4EAC-A2B1-BDD81B955994Q39299601-6523871F-F47B-461F-8D64-21609258B5B1Q39381430-27A8F449-47D6-47DA-82B0-4F6741E5EFD6Q41195003-8F34D50B-33F6-4B26-B218-1E0B4BBD899BQ46000473-F1683AF6-3901-410A-B333-CAAD4B1F54F7Q46308914-B4606946-29A0-4B98-8282-93CA066537EB
P2860
β-arrestin-selective G protein-coupled receptor agonists engender unique biological efficacy in vivo
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
β-arrestin-selective G protein ...... ue biological efficacy in vivo
@en
type
label
β-arrestin-selective G protein ...... ue biological efficacy in vivo
@en
prefLabel
β-arrestin-selective G protein ...... ue biological efficacy in vivo
@en
P2093
P2860
P50
P356
P1476
β-arrestin-selective G protein ...... ue biological efficacy in vivo
@en
P2093
Bronwen Martin
Diane Gesty-Palmer
Mi-Hye Lee
Stuart Maudsley
W Jim Zheng
William H Wood
P2860
P304
P356
10.1210/ME.2012-1091
P577
2013-01-11T00:00:00Z