Drug interactions modulate the potential for evolution of resistance.
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Evolutionary rescue: linking theory for conservation and medicineViral quasispecies evolutionCombination therapies for combating antimicrobial resistanceCombination therapeutics in complex diseasesOptimal drug synergy in antimicrobial treatmentsTwo-drug antimicrobial chemotherapy: a mathematical model and experiments with Mycobacterium marinumGenetic and genomic architecture of the evolution of resistance to antifungal drug combinationsResource competition may lead to effective treatment of antibiotic resistant infectionsA population model evaluating the consequences of the evolution of double-resistance and tradeoffs on the benefits of two-drug antibiotic treatmentsInsect Antimicrobial Peptide Complexes Prevent Resistance Development in BacteriaPopulation Density Modulates Drug Inhibition and Gives Rise to Potential Bistability of Treatment Outcomes for Bacterial InfectionsSequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic EfficacyApplying evolutionary biology to address global challenges.Regulation of phenotypic variability by a threshold-based mechanism underlies bacterial persistence.Circuit-level input integration in bacterial gene regulation.Positive epistasis drives the acquisition of multidrug resistance.Investigation of antimicrobial use at a tertiary care hospital in Southern Punjab, Pakistan using WHO methodology.Nonoptimal microbial response to antibiotics underlies suppressive drug interactions.Drug interactions and the evolution of antibiotic resistance.Evaluation of Camellia sinensis catechins as a swine antimicrobial feed additive that does not cause antibiotic resistance.Multidrug evolutionary strategies to reverse antibiotic resistance.Comparative supragenomic analyses among the pathogens Staphylococcus aureus, Streptococcus pneumoniae, and Haemophilus influenzae using a modification of the finite supragenome modelTrade-offs between drug toxicity and benefit in the multi-antibiotic resistance system underlie optimal growth of E. coliImplications of stress-induced genetic variation for minimizing multidrug resistance in bacteriaAlternating antibiotic treatments constrain evolutionary paths to multidrug resistanceMalaria biology and disease pathogenesis: insights for new treatments.Selective advantage of resistant strains at trace levels of antibiotics: a simple and ultrasensitive color test for detection of antibiotics and genotoxic agents.Mapping differentiation under mixed culture conditions reveals a tunable continuum of T cell fatesNovel protocol for persister cells isolation.A window of opportunity to control the bacterial pathogen Pseudomonas aeruginosa combining antibiotics and phages.Imperfect drug penetration leads to spatial monotherapy and rapid evolution of multidrug resistance.Distinct growth strategies of soil bacteria as revealed by large-scale colony tracking.Prediction of resistance development against drug combinations by collateral responses to component drugs.Combination Effects of Antimicrobial Peptides.Antimicrobial combinations: Bliss independence and Loewe additivity derived from mechanistic multi-hit models.Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase.Selective pressure of antibiotic pollution on bacteria of importance to public health.When more is less: Emergent suppressive interactions in three-drug combinations.Antiretroviral dynamics determines HIV evolution and predicts therapy outcome.Evolutionary paths to antibiotic resistance under dynamically sustained drug selection
P2860
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P2860
Drug interactions modulate the potential for evolution of resistance.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Drug interactions modulate the potential for evolution of resistance.
@en
type
label
Drug interactions modulate the potential for evolution of resistance.
@en
prefLabel
Drug interactions modulate the potential for evolution of resistance.
@en
P2093
P2860
P356
P1476
Drug interactions modulate the potential for evolution of resistance.
@en
P2093
Jean-Baptiste Michel
Pamela J Yeh
Remy Chait
Robert C Moellering
Roy Kishony
P2860
P304
14918-14923
P356
10.1073/PNAS.0800944105
P407
P577
2008-09-24T00:00:00Z