Evolution of chromosomal regions containing transfected and amplified dihydrofolate reductase sequences.
about
Effect of chromosomal position on amplification of transfected genes in animal cellsCloning and expression of a human ATP-citrate lyase cDNAProtein reference mapping of dihydrofolate reductase-deficient CHO DG44 cell lines using 2-dimensional electrophoresis.Generation and characterization of chimeric antibodies against NS3, NS4, NS5, and core antigens of hepatitis C virusTranslational efficiency of polycistronic mRNAs and their utilization to express heterologous genes in mammalian cellsCo-amplified markers alternate in megabase long chromosomal inverted repeats and cluster independently in interphase nuclei at early steps of mammalian gene amplificationThe breakage-fusion-bridge (BFB) cycle as a mechanism for generating genetic heterogeneity in osteosarcoma.Stability of protein production from recombinant mammalian cells.Illegitimate DNA integration in mammalian cells.Analysis of the autonomous replication behavior in human cells of the dihydrofolate reductase putative chromosomal origin of replication.FISH-Based Analysis of Clonally Derived CHO Cell Populations Reveals High Probability for Transgene Integration in a Terminal Region of Chromosome 1 (1q13).Effect of hypoosmotic pressure on cell growth and antibody production in recombinant Chinese hamster ovary cell cultureChromosome breakage at a major fragile site associated with P-glycoprotein gene amplification in multidrug-resistant CHO cells.Chromosomal destabilization during gene amplification.Effects of methotrexate on transfected DNA stability in mammalian cells.Excision of N-myc from chromosome 2 in human neuroblastoma cells containing amplified N-myc sequences.Chromosome instability associated with human alphoid DNA transfected into the Chinese hamster genomeFormation of an inverted duplication can be an initial step in gene amplification.Coamplification and coexpression of human tissue-type plasminogen activator and murine dihydrofolate reductase sequences in Chinese hamster ovary cells.Moderate-level gene amplification in methotrexate-resistant Chinese hamster ovary cells is accompanied by chromosomal translocations at or near the site of the amplified DHFR geneGrowth-dependent expression of dihydrofolate reductase mRNA from modular cDNA genes.Ubiquitous Chromatin Opening Elements (UCOEs) effect on transgene position and expression stability in CHO cells following methotrexate (MTX) amplification.Genetic analysis of the clonal stability of Chinese hamster ovary cells for recombinant protein production.High levels of histone H3 acetylation at the CMV promoter are predictive of stable expression in Chinese hamster ovary cells.Transcriptome dynamics of transgene amplification in Chinese hamster ovary cells.Effects of clonal variation on growth, metabolism, and productivity in response to trophic factor stimulation: a study of Chinese hamster ovary cells producing a recombinant monoclonal antibody.Evaluation of stable and highly productive gene amplified CHO cell line based on the location of amplified genes.A study of monoclonal antibody-producing CHO cell lines: what makes a stable high producer?Cell attachment to microcarriers affects growth, metabolic activity, and culture productivity in bioreactor culture.Somatic cell fusion as a source of genetic rearrangement leading to metastatic variants.Selection strategies for the establishment of recombinant Chinese hamster ovary cell line with dihydrofolate reductase-mediated gene amplification.Delayed chromosomal instability induced by DNA damage.p27Kip1-mediated controlled proliferation technology increases constitutive sICAM production in CHO-DUKX adapted for growth in suspension and serum-free media.Osmoprotective effect of glycine betaine on foreign protein production in hyperosmotic recombinant chinese hamster ovary cell cultures differs among cell lines.Direct and inverted DNA repeats associated with P-glycoprotein gene amplification in drug resistant Leishmania.Identification of transgene integration loci of different highly expressing recombinant CHO cell lines by FISH.Development of a serum-free medium for the production of humanized antibody from Chinese hamster ovary cells using a statistical design.Development of a serum-free medium for dihydrofolate reductase-deficient Chinese hamster ovary cells (DG44) using a statistical design: beneficial effect of weaning of cells.Genetic analysis of heterogeneous sub-clones in recombinant Chinese hamster ovary cells.Development of a serum-free medium for a human immortalized fibroblast cell line (KMST-6/TNF) producing tumor necrosis factor-alpha (TNF-alpha) and growth inhibitory effects of its conditioned medium on malignant cells in culture.
P2860
Q22122413-37ACAAA3-8AE4-48F1-8945-1608B1E305F5Q24338504-A6E12F37-C961-4A78-A011-CAA1C69C5F9CQ33555425-F2CFDDF1-21A7-4ECF-97B1-6D9B70FA4FE0Q33909206-52200E58-B913-45C4-BF91-199E70075B5DQ33928764-C30071C3-CE03-4C92-ACD0-CD91D7585243Q33938099-52C835A4-AACC-4972-8AC7-7D52EB9DB558Q34555501-CDD71422-9BC8-40FC-B7ED-A0F016A5295DQ35046175-4A5D9D98-32AD-4101-A71D-B24F6090C893Q35214061-F5E0CFBC-C146-4EAF-B0BC-BF1AE098CE6EQ35934930-F678A0B4-C13B-4546-9AE4-D0B200F7D16AQ36148096-09CD61C1-616C-4EA3-B60E-85F43AFDEAE0Q36254966-432D6774-5FB1-4030-9D0F-91B875BD230CQ36662753-F2D67CAE-6642-4E13-8533-4E3E16B26C20Q36711517-4A0DC8CE-D888-4444-AC51-068C714C1B92Q36714714-D69B3480-DB22-4A56-A17D-F9D0676D0650Q36718316-FD20A9F4-44F4-4294-8F05-9E158636A193Q36844464-DA796BCA-EDCE-48A6-B565-1F6B017C225EQ36847076-603AA814-3815-4922-B692-9168CAB9EC30Q36903774-7E32B826-10D1-4E3F-8F07-FFB7782E9E20Q36940392-65FC3336-7848-491E-98E1-909FDA09CE30Q36978349-1E594C09-36D2-4132-9A85-8D79DFD70C3AQ38410973-8330FDAB-89A5-4917-850D-87A67F05637CQ38454977-8456EF34-81FE-4E1D-9C96-360B4385FD3CQ38778641-49CDB38B-E852-4D9F-9261-ED6335D65CF8Q39084008-EA2903FC-DABD-494E-814D-DB0592D126EFQ39493701-6D8C0E6C-9970-4BF2-820D-4B3C1DC9C6E6Q39918550-7687D8CF-139C-4692-9A35-D4BF9D1930A1Q39922200-43BA9754-7ECB-4A1E-88BF-F8A559B147F4Q40133154-E30677CC-F899-4BB8-B606-B8AA090545F6Q40191686-8485D801-362D-4E4D-8E71-0B9C51835CC6Q40437188-88A6E167-1D15-4E4B-9694-FB19EF641F06Q40656504-F4B6C8B7-1CD0-42E3-A9D7-7042A0140554Q40706888-CBB2D67D-A1FB-4FF0-8D21-821812CC7550Q40857044-5902229D-3FDA-4234-BADE-D0D15F822734Q41080505-D77CE93D-F7AB-4C32-8D22-6270A75E7973Q42326962-AD003DE4-4F14-41E8-80FF-F768C5B38C68Q42465879-0CC08633-E32A-49BB-97CB-5BEB56DF84FCQ42477259-FD051E15-F75F-4E3E-B778-0D9DE2F7D21BQ42776621-A639D3F4-17FE-4D84-A2E4-96777BB13597Q43615985-21906491-BFF0-4654-AA08-2D3F6161FCB7
P2860
Evolution of chromosomal regions containing transfected and amplified dihydrofolate reductase sequences.
description
1983 nî lūn-bûn
@nan
1983年の論文
@ja
1983年論文
@yue
1983年論文
@zh-hant
1983年論文
@zh-hk
1983年論文
@zh-mo
1983年論文
@zh-tw
1983年论文
@wuu
1983年论文
@zh
1983年论文
@zh-cn
name
Evolution of chromosomal regio ...... drofolate reductase sequences.
@en
type
label
Evolution of chromosomal regio ...... drofolate reductase sequences.
@en
prefLabel
Evolution of chromosomal regio ...... drofolate reductase sequences.
@en
P2093
P2860
P356
P1476
Evolution of chromosomal regio ...... drofolate reductase sequences.
@en
P2093
P2860
P304
P356
10.1128/MCB.3.4.699
P407
P577
1983-04-01T00:00:00Z