Variable content of double minute chromosomes is not correlated with degree of phenotype instability in methotrexate-resistant human cell lines
about
Assignment of the human dihydrofolate reductase gene to the q11----q22 region of chromosome 5Discrete human dihydrofolate reductase gene transcripts present in polysomal RNA map with their 5' ends several hundred nucleotides upstream of the main mRNA start siteGene amplification-associated cytogenetic aberrations and protein changes in vincristine-resistant Chinese hamster, mouse, and human cells.Human dihydrofolate reductase gene is located in chromosome 5 and is unlinked to the related pseudogenes.Development of methotrexate resistance in a human squamous cell carcinoma of the head and neck in cultureGene amplification in methotrexate-resistant mouse cells. IV. Different DNA sequences are amplified in different resistant lines.Evolution of chromosomal regions containing transfected and amplified dihydrofolate reductase sequences.Control of cellular gene expression during adenovirus infection: induction and shut-off of dihydrofolate reductase gene expression by adenovirus type 2Enhancement of methotrexate resistance and dihydrofolate reductase gene amplification by treatment of mouse 3T6 cells with hydroxyureaCorrelation of unstable multidrug cross resistance in Chinese hamster ovary cells with a homogeneously staining region on chromosome 1.Loss of unstably amplified dihydrofolate reductase genes from mouse cells is greatly accelerated by hydroxyureaEarly appearance and long-term persistence of the submicroscopic extrachromosomal elements (amplisomes) containing the amplified DHFR genes in human cell lines.Expression of phenotypic traits following modulation of colchicine resistance in J774.2 cells.Characterization of pyrazofurin-resistant HeLa cells with amplification of UMP synthase gene.
P2860
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P2860
Variable content of double minute chromosomes is not correlated with degree of phenotype instability in methotrexate-resistant human cell lines
description
1982 nî lūn-bûn
@nan
1982 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1982 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1982年の論文
@ja
1982年論文
@yue
1982年論文
@zh-hant
1982年論文
@zh-hk
1982年論文
@zh-mo
1982年論文
@zh-tw
1982年论文
@wuu
name
Variable content of double min ...... ate-resistant human cell lines
@ast
Variable content of double min ...... ate-resistant human cell lines
@en
Variable content of double min ...... ate-resistant human cell lines
@nl
type
label
Variable content of double min ...... ate-resistant human cell lines
@ast
Variable content of double min ...... ate-resistant human cell lines
@en
Variable content of double min ...... ate-resistant human cell lines
@nl
prefLabel
Variable content of double min ...... ate-resistant human cell lines
@ast
Variable content of double min ...... ate-resistant human cell lines
@en
Variable content of double min ...... ate-resistant human cell lines
@nl
P2093
P2860
P356
P1476
Variable content of double min ...... ate-resistant human cell lines
@en
P2093
P2860
P304
P356
10.1128/MCB.2.5.498
P407
P577
1982-05-01T00:00:00Z