Mutations in the herpes simplex virus DNA polymerase gene can confer resistance to 9-beta-D-arabinofuranosyladenine.
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A human cytomegalovirus mutant resistant to the nucleoside analog 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine (BW B759U) induces reduced levels of BW B759U triphosphateEffect of combinations of acyclovir with vidarabine or its 5'-monophosphate on herpes simplex viruses in cell culture and in miceStrains of varicella-zoster virus resistant to 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracilMechanism of resistance of human immunodeficiency virus type 1 to 2',3'-dideoxyinosineIdentification of amino acids in herpes simplex virus DNA polymerase involved in substrate and drug recognition.DNA sequence of the region in the genome of herpes simplex virus type 1 containing the genes for DNA polymerase and the major DNA binding protein.Herpes simplex virus mutants resistant to arabinosyladenine in the presence of deoxycoformycinMutation within the herpes simplex virus DNA polymerase gene conferring resistance to (R)-9-(3,4-dihydroxybutyl)guanine.Resistance of herpes simplex virus to 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine: physical mapping of drug synergism within the viral DNA polymerase locusGenetic characterization of the vaccinia virus DNA polymerase: cytosine arabinoside resistance requires a variable lesion conferring phosphonoacetate resistance in conjunction with an invariant mutation localized to the 3'-5' exonuclease domain.Genetic characterization of the vaccinia virus DNA polymerase: identification of point mutations conferring altered drug sensitivities and reduced fidelity.Engineered herpes simplex virus DNA polymerase point mutants: the most highly conserved region shared among alpha-like DNA polymerases is involved in substrate recognition.Pathogenicity of herpes simplex virus mutants containing drug resistance mutations in the viral DNA polymerase gene.Isolation and characterization of phosphonoacetic acid-resistant mutants of human cytomegalovirus.Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locusFine mapping and molecular cloning of mutations in the herpes simplex virus DNA polymerase locusCooperative effects between two acyclovir resistance loci in herpes simplex virus.A method for identifying the viral genes required for herpesvirus DNA replication.Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.Reduced in vivo mutagenesis by mutant herpes simplex DNA polymerase involves improved nucleotide selection.The novel anticytomegalovirus compound AIC246 (Letermovir) inhibits human cytomegalovirus replication through a specific antiviral mechanism that involves the viral terminase.Application of real-time PCR for determination of antiviral drug susceptibility of herpes simplex virus.Plaque autoradiography assay for the detection and quantitation of thymidine kinase-deficient and thymidine kinase-altered mutants of herpes simplex virus in clinical isolates.Characterization of a varicella-zoster virus variant with altered thymidine kinase activity.Genetic analysis of the susceptibility of mouse cytomegalovirus to acyclovir.Mutations in the herpes simplex virus DNA polymerase gene conferring hypersensitivity to aphidicolin.Effects of Acyclovir, Foscarnet, and Ribonucleotides on Herpes Simplex Virus-1 DNA Polymerase: Mechanistic Insights and a Novel Mechanism for Preventing Stable Incorporation of Ribonucleotides into DNA.Susceptibility of phosphonoformic acid-resistant herpes simplex virus variants to arabinosylnucleosides and aphidicolin.
P2860
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P2860
Mutations in the herpes simplex virus DNA polymerase gene can confer resistance to 9-beta-D-arabinofuranosyladenine.
description
1982 nî lūn-bûn
@nan
1982年の論文
@ja
1982年論文
@yue
1982年論文
@zh-hant
1982年論文
@zh-hk
1982年論文
@zh-mo
1982年論文
@zh-tw
1982年论文
@wuu
1982年论文
@zh
1982年论文
@zh-cn
name
Mutations in the herpes simple ...... eta-D-arabinofuranosyladenine.
@en
type
label
Mutations in the herpes simple ...... eta-D-arabinofuranosyladenine.
@en
prefLabel
Mutations in the herpes simple ...... eta-D-arabinofuranosyladenine.
@en
P2093
P2860
P1433
P1476
Mutations in the herpes simple ...... eta-D-arabinofuranosyladenine.
@en
P2093
P A Furman
P A Schaffer
P2860
P304
P407
P577
1982-03-01T00:00:00Z