Pak1 kinase links ErbB2 to β-catenin in transformation of breast epithelial cells.
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Targeting Cdc42 in cancerp21-Activated Kinase 2 Regulates Endothelial Development and Function through the Bmk1/Erk5 PathwayFRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated SchwannomasSmall molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents.PAK signalling during the development and progression of cancerReduced PAK1 activity sensitizes FA/BRCA-proficient breast cancer cells to PARP inhibitionOverexpression of PAK1 Correlates with Aberrant Expression of EMT Markers and Poor Prognosis in Non-Small Cell Lung Cancer.Molecular pathways: targeting RAC-p21-activated serine-threonine kinase signaling in RAS-driven cancersP21 activated kinase-1 mediates transforming growth factor β1-induced prostate cancer cell epithelial to mesenchymal transition.Group I Paks as therapeutic targets in NF2-deficient meningioma.The Cdc42 Effector Kinase PAK4 Localizes to Cell-Cell Junctions and Contributes to Establishing Cell Polarity.The Group I Pak inhibitor Frax-1036 sensitizes 11q13-amplified ovarian cancer cells to the cytotoxic effects of Rottlerin.A Derivative of Differentiation-Inducing Factor-3 Inhibits PAK1 Activity and Breast Cancer Cell Proliferation.Overexpression of PAK-1 is an independent predictor of disease recurrence in colorectal carcinomaMinireview: Mouse Models of Rho GTPase Function in Mammary Gland Development, Tumorigenesis, and MetastasisEffects of p21-activated kinase 1 inhibition on 11q13-amplified ovarian cancer cells.HER2 reduces breast cancer radiosensitivity by activating focal adhesion kinase in vitro and in vivo.p21-Activated protein kinases and their emerging roles in glucose homeostasis.Remarkable reductions of PAKs in the brain tissues of scrapie-infected rodent possibly linked closely with neuron loss.Targeting PAK1.Targeting group I p21-activated kinases to control malignant peripheral nerve sheath tumor growth and metastasis.Structure, biochemistry, and biology of PAK kinases.The P21-activated kinase expression pattern is different in non-small cell lung cancer and affects lung cancer cell sensitivity to epidermal growth factor receptor tyrosine kinase inhibitors.HER2 and β-catenin protein location: importance in the prognosis of breast cancer patients and their correlation when breast cancer cells suffer stressful situations.Sequestosome 1/p62 facilitates HER2-induced mammary tumorigenesis through multiple signaling pathways.Mechanisms of Cardiomyocyte Proliferation and Differentiation in Development and Regeneration.PAK1 mediates pancreatic cancer cell migration and resistance to MET inhibition.Molecular pathways: targeting the kinase effectors of RHO-family GTPases.Regulation of influenza virus replication by Wnt/β-catenin signaling.PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas.Group I Paks are essential for epithelial- mesenchymal transition in an Apc-driven model of colorectal cancer
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P2860
Pak1 kinase links ErbB2 to β-catenin in transformation of breast epithelial cells.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Pak1 kinase links ErbB2 to β-catenin in transformation of breast epithelial cells.
@en
type
label
Pak1 kinase links ErbB2 to β-catenin in transformation of breast epithelial cells.
@en
prefLabel
Pak1 kinase links ErbB2 to β-catenin in transformation of breast epithelial cells.
@en
P2860
P50
P1433
P1476
Pak1 kinase links ErbB2 to β-catenin in transformation of breast epithelial cells.
@en
P2093
Klaus P Hoeflich
P2860
P304
P356
10.1158/0008-5472.CAN-12-4453
P407
P577
2013-04-10T00:00:00Z