Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease.
about
Synapses and Alzheimer's diseaseCutting through the complexities of mTOR for the treatment of strokeTargeting disease through novel pathways of apoptosis and autophagyQD-Based FRET Probes at a GlanceIntraneuronal Aβ accumulation induces hippocampal neuron hyperexcitability through A-type K(+) current inhibition mediated by activation of caspases and GSK-3.Synaptic and extrasynaptic location of the receptor tyrosine kinase met during postnatal development in the mouse neocortex and hippocampusMolecular mechanisms of cognitive dysfunction following traumatic brain injuryEarly growth response 1 (Egr-1) regulates phosphorylation of microtubule-associated protein tau in mammalian brainTau-mediated synaptic damage in Alzheimer's diseaseNeuroprotective effects of donepezil against cholinergic depletion.Caspase-3 activation as a bifurcation point between plasticity and cell death.alphaII-Spectrin breakdown product cerebrospinal fluid exposure metrics suggest differences in cellular injury mechanisms after severe traumatic brain injury.Chronic treatment with anesthetic propofol improves cognitive function and attenuates caspase activation in both aged and Alzheimer's disease transgenic miceOlfactory epithelium amyloid-beta and paired helical filament-tau pathology in Alzheimer disease.Cayman ataxia-related protein is a presynapse-specific caspase-3 substrate.Synaptic dysbindin-1 reductions in schizophrenia occur in an isoform-specific manner indicating their subsynaptic location.Isoflurane induces endoplasmic reticulum stress and caspase activation through ryanodine receptorsAβ1-42 monomers or oligomers have different effects on autophagy and apoptosisCaspase-3 activation is required for reovirus-induced encephalitis in vivo.Oligomeric Aβ-induced synaptic dysfunction in Alzheimer's disease.Taking aim at Alzheimer's disease through the mammalian target of rapamycinGamma secretase-activating protein is a substrate for caspase-3: implications for Alzheimer's diseaseCaspases: therapeutic targets in neurologic disease.In vitro neuroprotective potential of four medicinal plants against rotenone-induced toxicity in SH-SY5Y neuroblastoma cells.A genome-wide scan reveals important roles of DNA methylation in human longevity by regulating age-related disease genes.Characterization of Aldh2 (-/-) mice as an age-related model of cognitive impairment and Alzheimer's diseaseRelationship between the FAS gene A-670G polymorphism and Alzheimer's disease: a meta-analysis.Mechanism of Oxidative Stress and Synapse Dysfunction in the Pathogenesis of Alzheimer's Disease: Understanding the Therapeutics StrategiesCdk5 protein inhibition and Aβ42 increase BACE1 protein level in primary neurons by a post-transcriptional mechanism: implications of CDK5 as a therapeutic target for Alzheimer disease.Chronic corticosterone exposure alters postsynaptic protein levels of PSD-95, NR1, and synaptopodin in the mouse brain.Overview and findings from the religious orders studyDiet and aging.Anti-autophagic and anti-apoptotic effects of memantine in a SH-SY5Y cell model of Alzheimer's disease via mammalian target of rapamycin-dependent and -independent pathways.A Critical Kinase Cascade in Neurological Disorders: PI 3-K, Akt, and mTOR.Oxidant stress and signal transduction in the nervous system with the PI 3-K, Akt, and mTOR cascadeAppoptosin is a novel pro-apoptotic protein and mediates cell death in neurodegeneration.mTOR: on target for novel therapeutic strategies in the nervous system.Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in β-amyloid generation and Alzheimer's disease.Melissa officinalis Acidic Fraction Protects Cultured Cerebellar Granule Neurons Against Beta Amyloid-Induced Apoptosis and Oxidative Stress.Apoptosis and in vitro Alzheimer disease neuronal models.
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Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease.
@en
type
label
Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease.
@en
prefLabel
Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease.
@en
P2093
P2860
P50
P1476
Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease.
@en
P2093
Julia W Cohen
Konrad Talbot
Li-Ying Han
Natalia Louneva
Robert S Wilson
P2860
P304
P356
10.2353/AJPATH.2008.080434
P407
P577
2008-09-25T00:00:00Z