Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease. - Wikidata - wikimedia - TriplyDB

Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease.

Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease.

http://www.wikidata.org/entity/Q36943100

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Synapses and Alzheimer's disease Cutting through the complexities of mTOR for the treatment of stroke Targeting disease through novel pathways of apoptosis and autophagy QD-Based FRET Probes at a Glance Intraneuronal Aβ accumulation induces hippocampal neuron hyperexcitability through A-type K(+) current inhibition mediated by activation of caspases and GSK-3.Synaptic and extrasynaptic location of the receptor tyrosine kinase met during postnatal development in the mouse neocortex and hippocampus Molecular mechanisms of cognitive dysfunction following traumatic brain injury Early growth response 1 (Egr-1) regulates phosphorylation of microtubule-associated protein tau in mammalian brain Tau-mediated synaptic damage in Alzheimer's disease Neuroprotective effects of donepezil against cholinergic depletion.Caspase-3 activation as a bifurcation point between plasticity and cell death.alphaII-Spectrin breakdown product cerebrospinal fluid exposure metrics suggest differences in cellular injury mechanisms after severe traumatic brain injury.Chronic treatment with anesthetic propofol improves cognitive function and attenuates caspase activation in both aged and Alzheimer's disease transgenic mice Olfactory epithelium amyloid-beta and paired helical filament-tau pathology in Alzheimer disease.Cayman ataxia-related protein is a presynapse-specific caspase-3 substrate.Synaptic dysbindin-1 reductions in schizophrenia occur in an isoform-specific manner indicating their subsynaptic location.Isoflurane induces endoplasmic reticulum stress and caspase activation through ryanodine receptors Aβ1-42 monomers or oligomers have different effects on autophagy and apoptosis Caspase-3 activation is required for reovirus-induced encephalitis in vivo.Oligomeric Aβ-induced synaptic dysfunction in Alzheimer's disease.Taking aim at Alzheimer's disease through the mammalian target of rapamycin Gamma secretase-activating protein is a substrate for caspase-3: implications for Alzheimer's disease Caspases: therapeutic targets in neurologic disease.In vitro neuroprotective potential of four medicinal plants against rotenone-induced toxicity in SH-SY5Y neuroblastoma cells.A genome-wide scan reveals important roles of DNA methylation in human longevity by regulating age-related disease genes.Characterization of Aldh2 (-/-) mice as an age-related model of cognitive impairment and Alzheimer's disease Relationship between the FAS gene A-670G polymorphism and Alzheimer's disease: a meta-analysis.Mechanism of Oxidative Stress and Synapse Dysfunction in the Pathogenesis of Alzheimer's Disease: Understanding the Therapeutics Strategies Cdk5 protein inhibition and Aβ42 increase BACE1 protein level in primary neurons by a post-transcriptional mechanism: implications of CDK5 as a therapeutic target for Alzheimer disease.Chronic corticosterone exposure alters postsynaptic protein levels of PSD-95, NR1, and synaptopodin in the mouse brain.Overview and findings from the religious orders study Diet and aging.Anti-autophagic and anti-apoptotic effects of memantine in a SH-SY5Y cell model of Alzheimer's disease via mammalian target of rapamycin-dependent and -independent pathways.A Critical Kinase Cascade in Neurological Disorders: PI 3-K, Akt, and mTOR.Oxidant stress and signal transduction in the nervous system with the PI 3-K, Akt, and mTOR cascade Appoptosin is a novel pro-apoptotic protein and mediates cell death in neurodegeneration.mTOR: on target for novel therapeutic strategies in the nervous system.Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in β-amyloid generation and Alzheimer's disease.Melissa officinalis Acidic Fraction Protects Cultured Cerebellar Granule Neurons Against Beta Amyloid-Induced Apoptosis and Oxidative Stress.Apoptosis and in vitro Alzheimer disease neuronal models.

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P2860

Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease.

http://www.wikidata.org/entity/Q36943100

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease.

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type

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Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease.

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prefLabel

Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease.

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The American Journal of Pathology

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Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease.

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Julia W Cohen

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Konrad Talbot

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Li-Ying Han

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Natalia Louneva

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Robert S Wilson

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P2860

A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

Drebrin, a dendritic spine protein, is manifold decreased in brains of patients with Alzheimer's disease and Down syndrome

Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease

Pathways towards and away from Alzheimer's disease

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

Disappearance of actin-binding protein, drebrin, from hippocampal synapses in Alzheimer's disease

Regulation of NMDA receptor trafficking by amyloid-beta

Apoptotic effect of caspase-3 cleaved tau in hippocampal neurons and its potentiation by tau FTDP-mutation N279K

The neuronal microtubule-associated protein tau is a substrate for caspase-3 and an effector of apoptosis

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173

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John Q. Trojanowski

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David A Bennett

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2008-09-25T00:00:00Z

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23283603

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18818379

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Alzheimer's disease

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2570138

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