Tissue-specific ablation of Prkar1a causes schwannomas by suppressing neurofibromatosis protein production.
about
Dinosaurs and ancient civilizations: reflections on the treatment of cancermiRNA-7 attenuation in Schwannoma tumors stimulates growth by upregulating three oncogenic signaling pathwaysMolecular mechanisms promoting the pathogenesis of Schwann cell neoplasmsA novel imaging-compatible sciatic nerve schwannoma modelNeoplasia: the second decade.Follicular thyroid cancers demonstrate dual activation of PKA and mTOR as modeled by thyroid-specific deletion of Prkar1a and Pten in mice.Cushing's syndrome and fetal features resurgence in adrenal cortex-specific Prkar1a knockout miceDual loss of rb1 and Trp53 in the adrenal medulla leads to spontaneous pheochromocytoma.Mouse models of endocrine tumours.Neural crest-specific loss of Prkar1a causes perinatal lethality resulting from defects in intramembranous ossificationDifferential role of PKA catalytic subunits in mediating phenotypes caused by knockout of the Carney complex gene Prkar1a.Thyroid-specific ablation of the Carney complex gene, PRKAR1A, results in hyperthyroidism and follicular thyroid cancer.The protein kinase A regulatory subunit R1A (Prkar1a) plays critical roles in peripheral nerve development.The War on Cancer rages on.Use of mouse models to understand the molecular basis of tissue-specific tumorigenesis in the Carney complex.Rac1 controls Schwann cell myelination through cAMP and NF2/merlin.Phosphodiesterase 8B and cyclic AMP signaling in the adrenal cortex.Rac1 is required for Prkar1a-mediated Nf2 suppression in Schwann cell tumorsMultistep phosphorylation by oncogenic kinases enhances the degradation of the NF2 tumor suppressor merlin.
P2860
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P2860
Tissue-specific ablation of Prkar1a causes schwannomas by suppressing neurofibromatosis protein production.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Tissue-specific ablation of Pr ...... bromatosis protein production.
@en
type
label
Tissue-specific ablation of Pr ...... bromatosis protein production.
@en
prefLabel
Tissue-specific ablation of Pr ...... bromatosis protein production.
@en
P2093
P2860
P356
P1433
P1476
Tissue-specific ablation of Pr ...... bromatosis protein production.
@en
P2093
Anat O Stemmer-Rachamimov
Chhavy Tep
Georgeta Mihai
Georgette N Jones
Graham F Kay
Ian D Tonks
Lawrence S Kirschner
Petra M Schmalbrock
Sung Ok Yoon
William H Towns
P2860
P304
P356
10.1593/NEO.08652
P577
2008-11-01T00:00:00Z